From #CancerEngineeringSummit: Natalie Artzi, PhD (@NatalieArtzi), of @harvardmed, shares how structural nanomedicine can maximize the safety and efficacy of cancer therapies, including mRNA-based treatments.
💡 Researchers from the @WyssInstitute have showed they can use messenger RNA to activate the pathway and trigger the immune system to attack tumors!
Check out the work from Dr. @NatalieArtzi's lab in PNAS: https://t.co/fueVk1TWXT
Press release: https://t.co/hVsOKaE6cN
Cancer's Own Machinery 'Hijacked' to Spark Anti-Tumor Response
The immune-activating molecule cGAMP reacts to the presence of dsDNA in the cells’ cytoplasm, causing the #immunesystem to fight the tumor
@NatalieArtzi@MassGeneralNews#melanoma#tumors
https://t.co/mZfahiERfA
Grateful to @EricTopol for highlighting the special issue on #Structural#Nanomedicine featuring our work on cGAS mRNA delivery to cancer cells to trigger immune activation. Exciting opportunities ahead!
Thank you @DrMTeplensky and @CHADNANO for including us in this issue!
Researchers harness tumor cells to boost antitumor immunity in preclinical cancer models, in a new @PNASNews study.
Read more: https://t.co/aarL0BfNBs https://t.co/1hrdY9uWn8 @NatalieArtzi@wyssinstitute
We keep getting better at controlling the immune system, with big implications for treating diseases
1. cGAS delivery via mRNA/nanoparticle revs up cancer immunotherapy https://t.co/946fpaUBim
2. Off-the-shelf CAR-T as good as patient-specific for lymphoma
https://t.co/F9DlI4uNll @adamfeuerstein
3. Structural immunotherapy https://t.co/OGMUgqVQyx
Cancer Cell Enzyme Activates Antitumor Immune Pathway
Tumors were eradicated in 30% of mice receiving cGAS #LNPs injected into the tumor, in combination with immune checkpoint blockade
@NatalieArtzi@MIT_IMES#immuneresponse#cancercells#cancertherapy
https://t.co/a2jIhLfB9v
I’m delighted to share our new perspective article, “33 Unresolved Questions in Nanoscience and Nanotechnology,” just published in ACS Nano.
This work charts a bold vision for the future of nanoscience and nanotechnology.
https://t.co/k1f0g6pTgE
Structure is the secret.
In today’s ACS Nano perspective, Chad Mirkin and a team of scientific leaders explain how carefully engineered nanomedicines could make treatments safer, smarter, and more effective.
https://t.co/jCOSDrdPTT
In a new commentary, researchers from the @BrighamWomens@wyssinstitute discuss the emerging era of structural nanomedicine.
Read more: https://t.co/B1j0zOSLHW @NatalieArtzi
"The emerging era of structural nanomedicine"
A new perspective from @CHADNANO, Milan Mrksich, and @NatalieArtzi (@Harvard) reveals that the structure of #nanomedicines is key to their therapeutic potency and regulatory success—not just their components.
https://t.co/fCvNzI1eZA
When women spend 25% more time in poor health than men, the news that the government is slashing funding to the pivotal Women's Health Initiative highlights the importance of supporting & talking about women's health.
Read more from @statnews: https://t.co/f7Z4SVOEsc
A new perspective from Chad Mirkin (@CHADNANO), Milan Mrksich, and Natalie Artzi (@NatalieArtzi) charts a bold future for precision nanomedicine.
Out now in Nature Reviews Bioengineering: https://t.co/eL7Z60G9bU
Our first panel session, Bold Science from ARPA-H, discussed how ARPA-H funding is pushing the limits of healthcare tech by embracing high-risk, high-reward research💥Thank you to panelists Natalie Artzi, R. Todd Constable, Clark Hung, and Mark Skylar-Scott 🙌 #BMEII2025