Arun K Anguraj Vadivel

Researcher 👨🏽‍🔬 The Hospital for Sick Children #Proteomics #Bioinformatics #Cancer Blockchain & AI enthusiast

[Arun K Anguraj Vadivel @arunkumaranAV]

remotes::install_github("arunkumaran07/Proteome")

[Arun K Anguraj Vadivel @arunkumaranAV]

The ProteomicsML R package has been upgraded

A modular toolkit for cancer proteomics from raw CSVs to biological insight:

Differential expression + volcano plots
Reactome GSEA
LASSO & Random Forest built in
Interactive wizard

https://t.co/m4omlR7Ole

[Arun K Anguraj Vadivel @arunkumaranAV]

Tumor-Targeted pan-RAS Inhibition as a Novel Biologic Therapy for Diffuse Midline Glioma https://t.co/UzEWWEhDFs

[Arun K Anguraj Vadivel @arunkumaranAV]

https://t.co/4HgptcxyeI

[Arun K Anguraj Vadivel @arunkumaranAV]

My talk #2 will be at the ECR competition on Tuesday at 9:10 am in Frontenac Ballroom. #HUPO2025 I am delighted to be selected as one of the finalists to present my work at the World Congress.

[Arun K Anguraj Vadivel @arunkumaranAV]

In Harbour room B

[Arun K Anguraj Vadivel @arunkumaranAV]

Interested in learning the basics of ML/AI models and how to implement them in (prote)omics? I will be hosting a workshop at HUPO2025 @hupo_org on Sunday at 10:15 am at the Westin Harbour Castle Hotel

[Arun K Anguraj Vadivel @arunkumaranAV]

Thank you ⁦@hupo_org⁩ Human Proteome Organization (HUPO) for the recognition, I will presenting my work at ECR Manuscript plenary session at HUPO2025 https://t.co/bRaD9zJZjK

[Arun K Anguraj Vadivel @arunkumaranAV]

A podcast on our recent findings in DMG https://t.co/pgwTtEV4zJ

[Arun K Anguraj Vadivel @arunkumaranAV]

The original article: https://t.co/KTpDSaT86r

[Arun K Anguraj Vadivel @arunkumaranAV]

Editorial: Commentary on our recent publication on DMG proteome and PTMs. Thank you, Dr. Duchatel and Dr. Nazarian, for your valuable comments and discussion on our findings and field. https://t.co/P8IsEQ6L7R

[Arun K Anguraj Vadivel @arunkumaranAV]

Great learning experience at the Blockchain Conference at the Old Toronto Stock Exchange! ⁦@Futurist_conf⁩ so many talents and promising startups in Canada 🇨🇦

[Arun K Anguraj Vadivel @arunkumaranAV]

@MattDun17 Thank you!

METTL13 is a promising target, not only in DMG but also in pancreatic and lung cancers!

It is also over expressed at protein levels across several pediatric brain tumors.

Hope someone can help us develop a drug.

[Arun K Anguraj Vadivel @arunkumaranAV]

#Proteomics #Methylation #Methylproteome

[Arun K Anguraj Vadivel @arunkumaranAV]

proteomic landscape of diffuse midline glioma highlights the therapeutic potential of non-histone protein methyltransferases https://t.co/KTpDSaT86r

[Arun K Anguraj Vadivel @arunkumaranAV]

4. EEF1A1 methylation is linked to poor prognosis, making METTL13 a promising therapeutic target for DMG & other incurable cancers.

Fighting DIPG /DMG together—because every child deserves a future.

[Arun K Anguraj Vadivel @arunkumaranAV]

@SickKidsNews @CHawkinsLab @OICR_news So happy to see the advancement of our proteomics work to the next stage