Kind of surreal to share that our manuscript (using organoids and in vivo models to highlight the requirement of Nkx2-1 to maintain progenitor capacity in AEPs) is out in @NatureComms (https://t.co/tcGcWdwrqJ), summarizing a large amount of my thesis work with
@DrWillZacharias.
Finally, thank you to our amazing collaborators/colleagues at @CincyChildrens, @CincyMSTP, @UCincyMedicine, @MDBCincy, and many more. None of this would have been possible without the huge amount of support we've received.
Kind of surreal to share that our manuscript (using organoids and in vivo models to highlight the requirement of Nkx2-1 to maintain progenitor capacity in AEPs) is out in @NatureComms (https://t.co/tcGcWdwrqJ), summarizing a large amount of my thesis work with
@DrWillZacharias.
We validate use of Tfcp2l1-CreERT2 for adult in vivo studies, with direct comparison to Axin2-CreERT2-tdt. Also, we show that organoids from Tfcp2l1+ adult epithelial cells clonally expand into organoids with similar structural/cellular complexity (compared to Axin2+ organoids).
Pretty awesome ending to my PhD with @DrWillZacharias – can’t say thank you enough. While it’s hard to leave some of these projects behind, I can’t wait to see the work coming out of the lab in the future. Now, back to medical school!