Crystal structure of the Fab fragment of the anti-IL-6 antibody I9H in complex with a domain-swapped IL-6 dimer (PDB code: 8YWQ) #molecularart#scivis@proteinimaging@dzine_ai
https://t.co/ziVrz0Re00
@fenguita@proteinimaging@dzine_ai Francisco, thanks for posting such a beautiful picture of our crystal structure! 💔
We will write a post about the article soon :)
Are you curious what is known about SLCs? And how they are related? We are enthusiastic to wrap up the series of four (4) manuscripts by presenting the data- and knowledge-derived functional landscape of human solute carriers #SLC : https://t.co/So4VmaGD34
@KhRRustamov@adaptyvbio Congratulations for 2nd place in the protein design competition!👏
That's awesome, especially since you were competing against experienced researchers (postdocs, etc.) from well-known teams.
Our new luciferase paper is now out! Luminescence is weak, and the organism (Enhygromyxa salina) was not known to be luminescent. Reviewers were very helpful to get everything right.
Congratulations to @Aynya5 (now in Groningen) and all coauthors!
https://t.co/dSsw6peIj5
We celebrate first first-author paper by @pricelesska���
Using super-resolution #PALM🔬, we showed that ChR2, protein used to control neuronal activity with light in lab and clinics, forms stable (WT) or transient (mutant) dimers in human cell membranes
https://t.co/300ZzYthnu
New thrilling preprint from our team!
🔸SMLM / qPALM🔬
🔸optogenetic tool, ChR2🧬🌟
🔸ChR2 dimers in the plasma membrane🔗🔒
🔸 monomerized ChR2 mutant🔗💥
🔸Kd for dimerization in cells
First first-author preprint for a science-hero @pricelesska!👏🥳
https://t.co/1pU0niJoK9
Mutagenesis of #FbFP#LOV domain:
🟠 22 variants with 486-512 nm emission maxima
🟠 three-channel imaging via spectral unmixing
🟠 two-channel fluorescence lifetime unmixing
https://t.co/5Kgc045vlh
Congratulations, @ivangushchin, @Aynya5, and all the authors!
@FPbase
Happy to share the Methods in Molecular Biology issue on Fluorescent Proteins 🌈🎉😀. Including many “much awaited” protocols on and about Fluorescent Proteins/applications. A big THANKS to authors across the globe for contributing. 👏🏻💐
https://t.co/0yCqaDfzKw
https://t.co/uh0JuvKN3n через @YouTube
Пропаганда настолько хорошо работала последние года в России, что миллионы поверили в нацистов, захвативших власть в Украине. Не думаю, что таких людей большинство, но много, особенно среди старшего поколе��ия.
Our short communication about Chloroflexus islandicus LOV is now published in BBRC 🎉 🥳 https://t.co/qaiNRIkCQv
Great team work from Ivan, Anastasia and everybody else!
Another day, another LOV domain color tuning paper 🥳 Red-shifted variants for two color imaging. Open access @jbiolchem https://t.co/1xryUBXab2 Great collaboration with IMET/IBG-1/IBI-1/7 @fz_juelich, and also @RWTH!
Now published in Proteins: Structure, Function, and Bioinformatics, access link: https://t.co/rlEjY35STK
Congratulations to Vera, Alina, @kirkovalev94, Ivan, @Aynya5, @AstashkinR, Valentin and me🥳
Color tuning of LOV domains isn't easy, but we have some ideas in the pipeline!
Хорошее обсуждение получилось. Мне было бы интересно послушать отдельное обсуждение про стоимость разработки лекарств и проблемы регулирования фарм. рынка; в частности, может ли помочь увеличение сроков действия патентов
New preprint: spectral tuning in flavin-binding fluorescent proteins. Two-color imaging using LOV domains is also demonstrated! https://t.co/GmCuQTKXG0