J Tyson

[J Tyson @b_chinnian5]

@IAmTimNguyen In two weeks it will seem old.

[J Tyson @b_chinnian5]

@Docjoshsoc It's notable that the pancreatic poster reports a median of the full maximum 34 encoded neoantigens in a course of intismeran:

[Ryan Williams @rrwilliams.bsky.social @rrwilliams]

An internal model at OpenAI has produced a claimed refutation of ETH! Russell Impagliazzo, Mohan Paturi, and I have been asked to help organize an open and independent examination of this claim. 1/4

[J Tyson @b_chinnian5]

A gap in the US regulatory framework is putting us at risk of a pathogenic avian flu recombination event with a human-to-human transmissible flu, according to Hotez.

[Prof Peter Hotez MD PhD DSc(hon) @PeterHotez]

Full interview here

[Noubar Afeyan @NoubarAfeyan]

Congratulations to the @moderna_tx and @Merck teams on the release of detailed phase 3 trial data for our mRNA therapy for melanoma. The results met every target we had set for success and meaningfully changed the trajectory of patients’ disease. Today, these results are numbers on a screen, but they represent real people who faced a deadly cancer and were given new hope thanks to breakthrough science.

I believe this study opens a new era in cancer medicine - one where treatments are personalized, targeted, and more effective than ever before.

[J Tyson @b_chinnian5]

@PeterDiamandis Terminator isn't sci-fi anymore.

[J Tyson @b_chinnian5]

@JackHadfield14 This is somewhat misleading-- Moderna wasn't restricting itself to vaccines. The platform is quite versatile.

[Prof. Feynman @ProfFeynman]

If our small minds, for some convenience, divide this universe, into parts — physics, biology, geology, astronomy, psychology, and so on — remember that nature does not know it!

[J Tyson @b_chinnian5]

@alz_zyd_ People who aren't in math or coding don't realize that AI and robotics is sooner or later going to make mincemeat of all professions.

[J Tyson @b_chinnian5]

@TJMeehan1 @ScottGottlieb You should listen to the audio, there was a lot of oral discussion of the point of how many patients were eligible for neoantigen treatment that wasn't in the slides.

[J Tyson @b_chinnian5]

@GamerFunni @Entoma2657 You can get a nobel prize in economics if you figure that out.

[J Tyson @b_chinnian5]

@T_wolfpoint That makes as much sense as claiming Trump wants to make America great again because he claims he does.

[J Tyson @b_chinnian5]

@MetricsTruther I agree 1-1 and onto are better. Can you keep straight which is the type-1 and type-2 error in statistics? I think both terms are examples type-3 errors, which is naming things badly.

[J Tyson @b_chinnian5]

@JialiangLiang @badinvestor99 @OverboughtWatch Yes, but 5 hadn't received the first dose of cancer vaccine yet.

[J Tyson @b_chinnian5]

@edtarnowski @MelindaBChu1 @lucas_nivon To be clear, they used a fixed machine learning model that was trained 10 years ago to select the neoantigens, and it was the same (pre-trained) model throughout the trials.

[J Tyson @b_chinnian5]

@gd_pete This is a moonshot. Perhaps just as spectacularly, the mRNA platform keeps pushing out new drug after new drug, at the swap of an mRNA sequence: covid, flu, rsv, cancer, next rare genetic diseases & autoimmune diseases, and then many more to come.

[J Tyson @b_chinnian5]

@ProfGLongMIA The individualized vaccine is a moonshot advance!

[J Tyson @b_chinnian5]

@TJMeehan1 @ScottGottlieb By "company", I meant Moderna, not Merck.

[J Tyson @b_chinnian5]

@TJMeehan1 @ScottGottlieb There was specific discussion of that at the company's post-ESMO webcast yesterday. If it's not still available on the company's presentations webpage, then you can listen to it and view the slides on the (free) QUARTR app on your phone.