Who says nothing great comes in the mail anymore? Our advance copy of Chronic Pain Reset arrived today! It’s all we’d hoped for and more. https://t.co/Q8Srb6fRtC
#ChronicPain#Wellness
Very interesting press release from @Merck this morning indicating that the #KN756 met its primary endpoint of improving pCR (pathological complete response) in patients with high-risk, early-stage HR+/HER2- #breastcancer
I am cautiously excited about this press release until I hear more because:
1️⃣We know that in HR+ (unlike in TNBC and HER2+) that not archiving a pCR does not always translate in poorer outcomes and so it is really important to analyze the EFS (Event-free survival; the co-primary endpoint) data in both the IO and SOC groups before making any definitive decision
2️⃣How tolerable/toxic is the addition of immunotherapy to SOC
3️⃣Which patients with HR+/HER2- truly benefit from the addition of IO?
(ie did all the patients in the eligibility criteria benefit or only a subset?)
Finally, It is a shame they did not include #lobular Histology for the following reasons:
1️⃣ In the KN28, 2/3 of responders to immunotherapy had #Lobular histology
2️⃣ The Gelato trial showed that immunotherapy led to so responses in #ILC
3️⃣ We have recently shown in our poster at #ASCO23 that 44% of #ILC are immune enriched (Abstract 579; https://t.co/hQ3FxKuoTI ; @BostonGeneCorp)
#bcsm @OncoAlert@LobularBCA@OncBrothers
https://t.co/GDI54jgj49
Students & residents in areas of the U.S. underserved by rheumatologists and rheumatology health professionals are invited to apply for our Choose Rheumatology Scholarship – Workforce Expansion Award to experience ACR Convergence 2023.
Apply by 8/1: https://t.co/LENamYK7TV
As a recipient of the Foundation's Innovative Research Award, Dr. Daniel White is investigating the effectiveness of delivering #telehealth physical therapy to people with #kneearthritis. Read more in the latest edition of The Foundation Voice. https://t.co/n1jNqQA84g
🧑🤝🧑 To support patients, caregivers, and healthcare professionals in managing #rheumatic and #musculoskeltal diseases (RMDs), #EULAR produces Lay versions of its Recommendations.
🌍EULAR's Lay summaries and translations can be found here 👉https://t.co/Ix4ibtkjVk
Happy to share our @MDAndersonNews newly published paper about #lobular_breast_cancer in the European Journal of Cancer
Our study looked at the prognostic value of LCIS (Lobular Carcinoma In Situ), a facultative precursor of #ILC, when found at the time of diagnosis of #ILC
3 Key points from the study:
1️⃣ LCIS co-occurs with ipsilateral #ILC in 45% of the cases at the time of diagnosis
2️⃣ Pure #ILC tend to be associated with higher stages at diagnosis compared to ILC+LCIS
3️⃣ Absence of LCIS at the time of diagnosis of #ILC is a poor prognostic factor
IMO (In accordance with our #ILC pathologist @LP_Middleton) 👉🏻 All pathology reports should indicate whether LCIS is present or absent when reporting a diagnosis of #ILC
#EndCancer #bcsm #lobmob @LobularBCA@LobularBCUK@LobularIreland@elbcc@lobbccanada @drmediget @DrDebuTripathy
Link 👉🏻 https://t.co/0Hxxx2gZ1K
Our ACR Convergence Awards recognize scholarship among aspiring rheumatology professionals and provide an opportunity to experience the field firsthand at ACR Convergence 2023.
Applications due 8/1 by 5 PM ET → https://t.co/pFAhALkh8D
📰 HOT OFF THE PRESS!
Take a look at the Abstract Press Release published at #EULAR2023 about patient organisations driving change in rheumatology!
Read the #eularPressRelease now! 👉 https://t.co/lHuReqsTyt
#Rheumatology#PressRelease
Conditions that affect women more than men garner less funding. But boosting investment could reap big rewards. https://t.co/kIFpBkIGqo @REMEDY_center#eularHPR
A cute one to enjoy with your morning tea!🫖 What is the best single intervention to control visceral fatmass? 🤠 Exercise or restriction of calories? 💪 https://t.co/n4PksQu6cg