The Evolving Landscape of Amyloid Research
#amyloid#amyloidosis#AI#NLM
PROTEINS: Structure, Function, and Bioinformatics | Protein Science Journal | Wiley Online Journal https://t.co/lVzLqXGk63
Generation of two induced pluripotent stem cell lines from patients with cardiac amyloidosis carrying heterozygous transthyretin (TTR) mutation
https://t.co/Ur40DgRveN
Presented at #ESCardio:
Among patients with transthyretin amyloidosis with cardiomyopathy, the risk of death from any cause and recurrent cardiovascular events was lower with vutrisiran treatment than with placebo. Full HELIOS-B trial results: https://t.co/3MZy3lLznK
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#AHA100years@AHAScience@GenPrecisionMed
Among nearly 1M in Europe getting CT scans at 10-22y (without cancer diagnosed 1y after CT) followed mean 7.8y, there was a dose-dependent response of radiation exposure to heme malignancy risk.
Would suspect higher rates of clonal hematopoiesis as well...
https://t.co/8Riumxj34B @NatureMedicine
An analysis of Tafamidis in Transthyretin Cardiomyopathy Clinical Trial found tafamidis 80 mg, compared w/ placebo, attenuated the decline in left ventricular systolic & diastolic function in patients w/ transthyretin amyloid cardiomyopathy over 30 mos. https://t.co/1J8xvup4w3
Absolutely inspired by the profound and motivational words by my mentor @Joseph_C_Wu, AHA president. Grateful for the chance to contribute to cardiovascular research in this remarkable lab. Thrilled to be part of this history! #AHA23@American_Heart@AHAScience