Brian Coyne

[#TuckFrump @realTuckFrumper]

I’m happy to share this because I don’t care what side of the aisle you sit on, this is a fact.

Speaker Mike Johnson this is for you.
Concerning Social Security payments, my contributions were made for over 50 years on every salary I received. From my first part time job until I retired. I always had a job.

The Social Security check is now (or soon will be) referred to as a "Federal Benefit Payment?" I'll be part of the one percent to forward this.I am forwarding it because it touches a nerve in me, and I hope it will in you. Please keep passing it on until everyone in our country has read it.

The government is now referring to our Social Security checks as a "Federal Benefit Payment." This isn't a benefit. It is our money paid out of our earned income! Not only did we all contribute to Social Security but our employers did too.

It totaled 15% of our income before taxes.
Congress took our money and used it elsewhere. They forgot (oh yes, they knew) that it was OUR money they were taking.

They didn't have a referendum to ask us if we wanted to lend the money to them. And they didn't pay interest on the debt they assumed. And recently they've told us that the money won't support us for very much longer. And now, to add insult to injury, they're calling it a "benefit", as if we never worked to earn every penny of it.

Just because they borrowed the money doesn't mean that our investments were a charity!

Let's take a stand. We have earned our right to Social Security and Medicare. Demand that our legislators bring some sense into our government.

Find a way to keep Social Security and Medicare going for the sake of that 92% of our population who need it. Then call it what it is: Our Earned Retirement Income.
99% of people won't forward this to their timelines…..will you?

Please, for the sake of our country, repost this.

[Duke Health @DukeHealth]

Big news for the Triangle! Duke Health and @UNC_Health_Care and Duke Health announce a new level of care - a state-of-the-art children's hospital. When it comes to caring for our community, we're stronger together. More: https://t.co/DKMQBbGf8h

@Duke_Childrens

[Michael Johnson @MJGold]

Good accurate explainer of the effects on the body of sprinting 400 meters. Understanding this process was key to me breaking the WR and consistently running 43 seconds.

[euan ashley @euanashley]

Exercise may be the single most potent medical intervention ever known. Its benefits in prevention outstrip any known drugs: 50% reduction in the risk of cardiovascular disease, 50% reduction in the risk of many cancers, positive effects on mental health, pulmonary health, GI health, bone health, muscle function. You name it. Exercise helps. In fact, the ability to exercise over long distances was likely key to our evolution as a species because the availability of densely caloric foods due to persistence hunting allowed our energy-avid brains to enlarge. And yet, we have had very little insight into the molecular basis of these magical effects...until now!

Published in yesterday's Nature and featured on the cover was work from our consortium that represents the culmination of a couple of decades of pitching ideas to the NIH, forming a consortium, planning experiments, executing those experiments, and analyzing data at unprecedented scale, all aimed at enhancing our understanding of the molecular transducers of exercise.

It was a major effort from so many in our consortium (playfully named MoTrPAC) and is the first landmark paper of many more to come. This first paper focused on the multi-tissue, multi-omics of treadmill exercise in rats. Specifically, we report the effects of eight weeks of treadmill running on the transcriptome, the epigenome, the proteome, the metabolome, the lipidome and the immunome of a broad range of tissues (in fact, 9,466 assays across 19 tissues, 25 molecular platforms, and 4 training time points).

The result is the most comprehensive molecular map of exercise ever created. At Stanford, my colleague @MWheelerMD and I co-lead the bioinformatics center and it was our team's duty and privilege to ingest the data, QC the data, help analyze the data, and make the data available to the world. Various tools available at our data hub allow you to explore the data, visualize it, and download it for your own use.

Have fun! And stay tuned for human data that will be coming.

So many people to thank who made this possible (see the paper for details). Special shout out to the primary analysts and authors: David Amar, Nicole Gay, & Pierre Jean Baltran.

Paper: https://t.co/0nhXdfhxx0
Data hub: https://t.co/NxTHsVdfRp

[CEPA @CEPAupdates]

Learn about the importance of physical activity in non-alcoholic fatty liver disease (NAFLD) with leading expert, Dr. Stine, at the upcoming conference. Earn 5 CECs and take advantage of the discounted registration rates!

#CEPAAnnualVirtualConference #CEPA #ACSMCEPA

[Mark Kittipibul MD @vkittipibul]

Why VC relevant?

⬇ splanchnic VC can ⬆ cardiac preload/stress volume ➡ADHF by volume redistribution with unchanged total volume

SNB is shown to ⬇ cardiac pressures/volumes. It is thought to be 2/2 ⬆ splanchnic VC (not proven).

What happens to VC surrogates?

(2/7)

[Mark Kittipibul MD @vkittipibul]

Excited to share our work in @JAHA_AHA !
https://t.co/Ddtex1dwjI

We proposed and evaluated 4 surrogates of (splanchnic) venous capacitance (VC) post-splanchnic nerve block (SNB)

1️⃣ BP changes w/ Valsalva
2️⃣ IVC
3️⃣bendopnea
4️⃣Hemoconcentration

Follow 🧵 to learn more

(1/7)

[U.S. Soccer Men's National Team @USMNT]

Cade Cowell breaking all the ankles 👀

🎥 » @FOXSoccer

[Working@Duke @WorkingatDuke]

Duke Molecular Physiology Institute's Bryan Coyne captured this moment of three generations enjoying Edisto Island, SC.

Share your #DukeTimeOff photos for a chance at prizes from @DukeLemurCenter @DukeUnivStores & @WashingtonDuke https://t.co/c5pTWMAd1p

@bcoynercep @DukeMPI

[Anthony Peters @aepetersMD]

Excited to share this perspective. Exercise interventions have become foundational therapies in HFrEF and HFpEF, but remain underutilized. Looking forward to further testing/implementing current regimens (i.e. REHAB-HFpEF) and to studying new paradigms to improve sustainability.

[Dan Go @CoachDanGo]

5 exercises I'm doing to build stronger knees:

[Brian Coyne @bcoynercep]

@girdley Very true. Other countries are trying to duplicate some of this and buying US companies and land is one strategy.

[Michael J. Ackerman MD,PhD @MJAckermanMDPhD]

From its conception by ⁦@sday_hcm⁩, Dr. Lampert ⁦@Yale⁩, & me 10 yrs ago, the first results of LIVE-#HCM have been just released #ACC23. There was NO signal of increased risk among the 699 patients doing vigorous #exercise compared to the 961 who were less active!

[Duke Health @DukeHealth]

Duke is proud to be recognized as the #1 program in the U.S. for #hearttransplants in 2022, and the only program in the Southeast to transplant more than 1,800 heart and heart-lung transplants.

@DukeHeartCenter | @DukeCTSurgery

[Brandi Bottiger @brandi_bottiger]

Great Job to all. #cometoduke

[Brian Coyne @bcoynercep]

@VTEX551 Somebody had too much tryptophan 😆😂😂😂

[Brian Coyne @bcoynercep]

Exercise Physiologist position open in Duke's Cardiac Diagnostic Unit. Testing position in all areas of cardiopulmonary testing.

[Brian Coyne @bcoynercep]

Duke's Cardiac Diagnostic Unit has an Exercise Physiologist opening and is currently reviewing applications. Our great team performs stress testing from 6MW up to invasive cardiopulmonary testing. Master's degree required with ACLS and ACSM CCEP certification. Come join our team!

[Brian Coyne @bcoynercep]

https:/careers.duke.edu/job-invite/206529/

[Brian Coyne @bcoynercep]

https:/careers.duke.edu/job-invite/206529/

[JACC Journals @JACCJournals]

⬆️ self-reported MVPA during Tx for human epidermal growth factor receptor 2–positive breast cancer assoc. w/ better #QoL & diastolic/systolic LV function measures during Tx & better post-Tx cardiorespiratory fitness. https://t.co/fxCvw9ZMVL

#JACCCardioOnc #CardioOnc #BCsm #BCAM