@UsingLyft Many guys cried abkut that whole geoup leader thing but it is true u can tell by the body kanagueg who the group leader is among males and its easy to tell for both guys and girls
An experimental lung disease drug developed using artificial intelligence showed promise in reversing biological signs of aging, according to its developer Insilico.
Longevity enthusiasts have long embraced the repurposing of existing medications to delay aging. Read more: https://t.co/40sJIaIGdD
📷: Lam Yik/Bloomberg
Holy moly. An AI-designed drug just showed signs of reversing biological age in humans. 👀
"Researchers just analyzed blood samples from 42 patients with idiopathic pulmonary fibrosis treated in a Phase 2a trial of rentosertib, a TNIK-targeting drug discovered and designed with the help of generative AI."
"Across 2,841 blood proteins, all 6 independently developed proteomic aging clocks showed shifts toward younger predicted biological age in rentosertib-treated patients compared with placebo."
"The strongest effects appeared at Week 4. The 30 mg twice-daily group produced the broadest agreement across aging clocks, while the 60 mg once-daily group showed a 2.71–3.46 year reduction across all 4 chronological aging clocks."
"Researchers also compared the protein changes with data from 55,319 UK Biobank participants and found that rentosertib shifted age-associated protein-expression patterns toward younger profiles, alongside changes in cellular senescence, growth-factor signaling and metabolism."
"The results suggest aging clocks could potentially be integrated into ordinary clinical trials to identify geroprotective drugs years or even decades faster than waiting for lifespan outcomes," the researchers propose.
Anti aging research is accerating faster than ever due to AI 💚!
This is a major milestone in the age of AI and toward our ultimate goal of completely reversing aging!
@InSilicoMeds developed the first AI drug, Rentosertib, now in a Phase 3 clinical trial, and it just showed something remarkable: a reversal of biological age in people!
Six different aging clocks, developed by six independent groups, all showed reversal after just 12 weeks of treatment, with participants measuring 3–4 years younger biologically!
Congratulations to my friend Alex and the entire @InSilicoMeds team on this landmark achievement!