The biggest lie (even w/lots of competition) was pretending natural immunity doesn't exist. Many things flow from this, not least that it kept "essential workers" who got covid from reaping their due reward: recognized immunity. @andrewbostom@VPrasadMDMPH@AlexBerenson
In Israel, vaccinated individuals had 27 times higher risk of symptomatic COVID infection compared to those with natural immunity from prior COVID disease [95%CI:13-57, adjusted for time of vaccine/disease]. No COVID deaths in either group.
https://t.co/hopImCD1D0
@NCM4Ever@ProductionKate Hard to see how they can mandate the bivalent (to someone with any vax at all prior) given the supporting evidence cited by FDA refers to single dose monovalent:
@NCM4Ever@ProductionKate FDA wording is oddly obscure, but sure looks like they are saying enough immunity (in the unvaccinated) that one dose of bivalent (i.e. the only approved vax now) is all that is recommended to unvax'd. They quote evidence of monovalent single dose in prior infected.
@ITGuy1959 It's been quite a while now since pediatricians became "interventionist" in family life and child-rearing. When every visit includes (now standard professional practice) invasive questions, and parents are asked to leave the room (starting 12-ish?), this isn't just medical care.
Both @Yale and @Harvard require "up-to-date as defined by CDC", then H goes on to say eligible 3 months after covid+, and Yale just says need bivalent. BUT CDC says natural immunity counts! i.e. if covid+ AFTER all doses recommended THEN "up-to-date".....(when did cdc change? )
@RetsefL This is the fundamental problem: transfection can happen in almost any cell type (unlike SARS2 infection which needs ACE2 receptor). If LNPs not localized then you can have immune response and cell destruction anywhere they go. Not like a normal vax.
@bee_cuds@ZacBissonnette FYI, here is the Thai study -- prospective study, male and female age 13-18, number in study 301. Table below show details for 7 significant cases, only 1 meets full myo dx. https://t.co/bU9JwhMeD0
@bee_cuds@ZacBissonnette Yes, no doubt your case more severe and more significant. However elevated troponin means some cell damage, and we have no idea what the long term implications are in a young person. 1/300 with even mild heart inflammation is too high.
@KrugAlli BTW while the data for myo risk for young men is the most clear, by putting so much emphasis on young males we risk missing that young women also have elevated risk. I strongly suspect pericarditis is severely underdx'd (no blood marker, tests often neg) supported by Thai study.
@anish_koka Another important difference: mRNA and novavax both transfect cells to display spike, but the difference re SARS2 infection is that the cells types transfected are almost unlimited (no ACE2 needed). Now that we know LNPs travel extensively, this can have variety of impacts.