Ricardo Bernardino

[Patrick Collison @patrickc]

New project: https://t.co/0mvpzkysHb.

More: https://t.co/G5af6WXdTL.

[Eric Topol @EricTopol]

We've seen the Shingles vaccine is linked with reduced risk of Alzheimer's and dementias in 4 large natural experiments.
Today, the potential of high-dose flu vaccines vs standard dose for the same in a large retrospective age 65+ cohort [N>160,000). More pronounced in women (like Shingles vaccine)
https://t.co/dxYzURf7QH

[TIME @TIME]

With the rise of new tools in molecular biology, it’s becoming clear that viruses and other pathogens can remain in the body or otherwise affect its workings for a surprisingly long time https://t.co/d3VNRILaTA

[Norn Group @NornGroup]

Multiple lines of evidence are converging on the idea that viruses you picked up decades ago might quietly be driving age-related diseases.

We've known for a few years that EBV raises MS risk 32-fold, and that molecular mimicry between an EBV protein and nerve insulation likely triggers brain autoimmunity. What remained unclear was why some people persistently carry EBV and others don't.

A new paper in @Nature from the @RyanDhindsa (whose lab has been supported by @impetusgrants) and @CalebLareau labs answers that at population scale. They mined ~735,000 human genomes for traces of Epstein-Barr virus, using reads of viral genomes that existing pipelines were throwing out as junk, and found that ~10% of people carry detectable EBV DNA in blood.

Carrying persistent EBV is associated with variable antigen processing, and the broader genetic architecture of viral persistence shares a component with lupus, rheumatoid arthritis, and type 1 diabetes.

Meanwhile, a separate line of very recent evidence is also pointing in that direction. The shingles vaccine, targeting another persistent herpesvirus, is showing ~20% dementia risk reduction in quasi-randomized studies which has been replicated across multiple countries.

There seems to be more at the intersection of immunity and age-related disease than we initially thought.

[Ricardo Bernardino @bernardino_]

@luisjorge Fica a 15.99 por mês

[Samuel Hume @DrSamuelBHume]

10 breakthroughs in medicine in 2025

Read it here: https://t.co/YyaYTKd3Cs

[Prof. Akiko Iwasaki @VirusesImmunity]

Check out our new review, "The lingering shadow of epidemics: post-acute sequelae across history" by Drs. Christine Miller and @jannamoen. We highlight historical accounts of post-acute infection syndromes (PAIS) through the centuries 👇🏼 #LongCOVID
https://t.co/gCS7nmVKUW

[Patrick Collison @patrickc]

Came across this summary that pulls together some of the recent findings on the links between commonplace (including ostensibly "harmless") pathogens and long-term harm to human health. The war on infectious diseases is far from over!

[Olenka Sayko @coco_chatel]

So let me get this straight: COVID is a bioweapon that leaked out of a Chinese lab. But it’s also just a cold. But still a bio weapon. But we’re not going to do ANYTHING to mitigate its spread. Like not even filtering the air to keep a supposed bioweapon from spreading?

[Ricardo Bernardino @bernardino_]

@HarrySpoelstra I remember seeing this a while back https://t.co/UuvIvwbIPR

[Eric Topol @EricTopol]

We know Covid is associated with a higher subsequent rate of autoimmune diseases. A new report from >1.7 million Singaporean adults concludes "Booster vaccination appeared to mitigate the risk of long-term autoimmune sequelae."
https://t.co/TVG01zJSto

[Ricardo Bernardino @bernardino_]

@F_Brito_Bastos Try https://t.co/89zNt46PNx

[Ricardo Bernardino @bernardino_]

@luisjorge Lembrei-me disto (1:20)

[Rui Rocha @ruirochaliberal]

🔴🔵 Intervenção no debate do Estado da Nação.

[Ricardo Bernardino @bernardino_]

@45graus @ReiseSousaLab Recomendo este livro https://t.co/Xq7KvkYfVP. E também os vídeos dos mesmos autores https://t.co/be4rc4nrtI

[Ricardo Bernardino @bernardino_]

@adescafeum Entrou no metaverse

[Ricardo Bernardino @bernardino_]

@CatiaM_Carvalho @catiabruno Notion, Roam research ou Obsidian são melhores opções

[Ricardo Bernardino @bernardino_]

@jgrahamc I’ve also bought Azul and Ticket to Ride. Other: The Crew, Mysterium Park, Splendor, Dominion, Kamisado, Codenames

[WIRED Science @WIREDScience]

Romain Grosjean’s F1 car slammed into a wall at 137 mph and burst into flames. He walked away because of decades of work by unsung scientists and engineers. https://t.co/m0gHx9Msgh

[Ricardo Bernardino @bernardino_]

@Cat_poppe @axsenpai8 https://t.co/Mtd3VRMtP6 isto?