BEVITAL is a company offering analyses of direct and functional biomarkers, including biomarkers of vitamin and nutritional status, inflammation and lifestyle.
In 2023, our scientists at BEVITAL have been involved in a multitude of exciting projects. We would like to thank our collaborators and invite everyone to explore our list of recent publications. PDF versions of these articles can be provided upon request. https://t.co/GI4uzFtKUd
Introducing next-generation proteomics to your multi-omics studies: novel insights into inflammation and immune activation. Join the Bevital and #Olink seminar in Bergen, 28th September 2023. https://t.co/0jPQ9xrPKj
The seminar will also be online: https://t.co/YhCBYvprWS
This study found sex-specific responses after high-dose omega-3 supplementation in circulating markers of glycemic control/insulin sensitivity, which improved in females but worsened in males.
https://t.co/MyxSn8OwBw
This study found that elevated plasma methylmalonic acid, a marker of vitamin B12 deficiency, was associated with an increased risk of acute myocardial infarction and mortality in patients with suspected or verified coronary heart disease. #MMA#AMI#CHD
https://t.co/wFOQzWEW4D
Reduced SLC7A10 activity strongly affects the flux of #BCAAs in adipocytes, which may fuel continued lipogenesis during insulin resistance, and be reflected in increased circulating levels of the valine-derived catabolite #3-HIB.
https://t.co/STjjznJoZ5
In patients with suspected stable angina pectoris, treatment with calcium channel blockers was associated with increased mortality risk primarily among patients not treated with B vitamins.
https://t.co/iD7sZnpJUo
Patients with AD had higher concentrations of #kynurenic acid and picolinic acid. Higher concentrations of KA were associated with slower progression of AD. Activation of the #kynurenine pathway's neuroprotective branch may be an adaptive response in AD.
https://t.co/JNRDHTLtrV
#3-HIB is associated with insulin resistance and #T2D, but implicated mechanisms are poorly understood. โThese data implicate the hepatic valine/3-HIB pathway in mechanisms of fatty liver, reflected in increased plasma 3-HIB concentrations [...].'
https://t.co/VWPcohHeoc
A healthy Nordic diet was associated with plasma concentrations of several metabolites of the #choline oxidation pathway, but effect sizes were moderate.
#targeted#metabolomics at @BevitalAS
https://t.co/pC5zPTIqFB
BEVITAL AS has become a service provider of #OlinkProteomics and offers Target96&48 protein panels for high-quality proteomics.
https://t.co/72Y0ANXMAu
The effect of vitamin B12 supplementation during pregnancy on infant growth and development was investigated in a community-based trial in Nepal. Although B12 deficiency was prevalent, supplementation did not improve infant growth or neurodevelopment. https://t.co/0z1jCeBOuM
Overweight and #obesity are associated with a systemic elevation of #kynurenine pathway metabolic flux and accumulation of most downstream metabolites in persons with #MultipleSclerosis
https://t.co/OW6w8NLva0
Neopterin, CRP, tryptophan and #kynurenines were analyzed in cohorts of the #lungcancer Cancer Cohort Consortium. Inflammatory markers were related to metabolites located along the tryptophan-NAD axis, suggesting increased production of NAD from tryptophan
https://t.co/nSuksUdnx7
โCirculating TMAO did not predict long-term all-cause, CV, or non-CV mortality in patients with coronary heart disease or in community-based adults.โ
#targeted#metabolomics at @BevitalAS
https://t.co/cCiYzUsIUa
#Proteoforms of #cystatin C increased proportionally with total cystatin C in patients with chronic kidney disease. Prescription of corticosteroids and immunosuppressants had a significant effect on the distribution of proteoforms.
https://t.co/HH0nsaZZsj
Results from four cohorts suggest that aging activates the #kynurenine pathway systemically and in the brain, and a relatively stronger age-related increase of the potentially neurotoxic end-product quinolinic acid was found in brain.
https://t.co/u5dQWSoZpo
'Higher levels of the inflammatory biomarkers SAA, KTR and the PAr index were associated with greater LV mass index in psoriasis patients, indicating a role of chronic inflammation in LV remodelling evident even during treatment with TNF-ฮฑ blockers.'
https://t.co/mImfNCgFZ4
Specific acute phase reactants might be useful for risk stratification. A systematic review and meta-analysis was conducted of studies on serum amyloid A (SAA) in patients with COVID-19.
Read full article: https://t.co/Mjt3I5WRVr