Isermann Lab

Vascular Biologists, clotting enthusiasts, "Labormediziner".
Studying cellular mechanisms that are beyond blood clotting.

[Isermann Lab @beyondclotting]

Abstract submission is open for Lipid Meeting 2025! Submit your abstracts today! The deadline is 30.10.2025. More details visit:

https://t.co/Dd68rVTvAu

[Isermann Lab @beyondclotting]

The XXIV LIPID Meeting Leipzig will held December 10-12th, 2025 at Salles de Pologne, Leipzig, Germany.

The Meeting is organized by @UniLeipzig and @UKL_Leipzig has established itself as a renowned biennial meeting addressing cutting edge clinical and translational science.

[Isermann Lab @beyondclotting]

We are pleased to inform you about the XXIV Lipid Meeting which discusses aspects of cardiovascular diseases. The meeting will take place as an on-site conference on December 10-12th, 2023 at the Salles de Pologne in Leipzig, Germany.

Please visit: https://t.co/a37t1im8UV

[JTH @JTHjournal]

🤰VTE is a leading cause of morbidity and mortality in pregnancy.
This new JTH in Clinic Review covers evidences on VTE diagnosis and management, thrombophilia testing, and thromboprophylaxis in pregnancy. A must-read for clinicians!

✍️ @LaurenMerzMD @fniainle
Read it here:
https://t.co/StSZ1mkdq1

[Kidney International @Kidney_Int]

#Chronickidneydisease leads to microglial potassium efflux and inflammasome activation in the brain

https://t.co/ChU8fMR5oq

#OpenAccess #CKD
@UniLeipzig @HIMAG_Leipzig @HelmholtzMunich @OVGUpresse

[VU Chemical Biology @VICB_Vanderbilt]

Happing today! SPECIAL @VICB_Vanderbilt SEMINAR – August 21: @beyondclotting, Institute of Laboratory Medicine at @UKL_Leipzig Hospital: "Tissue Factor and Interferon-Alpha Receptor-1 Interaction Constitutes a Thrombo-Inflammatory Switch”
12:15 pm, 1220 MRB III

[Informationsdienst Wissenschaft - Nachrichten @idw_online_de]

Neue Studie der Universitätsmedizin Leipzig liefert wichtige Erkenntnisse aus der Grundlagenforschung, die für therapeutische Ansätze der chronischen #Nierenerkrankung dienen könnten. #Medizin #UniLeipzig @beyondclotting
https://t.co/8LQ1KUMmad

[Shrey Kohli @kohli_shrey]

Our very own @beyondclotting presenting latest work on TF and IFNAR1 as a thrombo-inflammatory switch #ISTH2024

[Shrey Kohli @kohli_shrey]

Had a great first day at #ISTH2024 with colleagues from our group and @beyondclotting. Looking forward to the next days!

[Kim Martinod @kmartinod]

Studying #endothelial #dysfunction as part of your research? The @isth Vascular Biology subcommittee would like to hear your input through the following survey as part of a new project led by co-chair @kohli_shrey. Please share!

[Shrey Kohli @kohli_shrey]

If you are working on endothelial dysfunction then we invite yoiu to participate in this 15 min ISTH SSC survey by vascular biology subcommittee to help us create consensus for minimum reporting of endothelial dysfunction. Please RT!

[Katalin Susztak @KSusztak]

Amazing line up for the first international diabetic kidney disease meeting. Incredible progress and more therapies on the horizon

[bender_lab @bender_lab]

🚨#PhD position available! Are you interested in cell #biology, #platelets, #optogenetics, #megakaryocytes? #DFG funded project at Department of Experimental Biomedicine I @Uniklinikum_Wue, Germany!

Apply now!

Please RT and share with potential applicants! Link next tweet!

[Isermann Lab @beyondclotting]

Using clinical cohorts and additional data from COVID patients, we show that this pathway is clinically relevant for infectious and non-infectious diseases.

[Isermann Lab @beyondclotting]

Using several in vitro, in vivo, in silico and ex vivo approaches, we show that TF directly binds to and interacts with IFNAR1 owing to its homology with IFNAR2 (a known ligand of IFNAR1)

[Isermann Lab @beyondclotting]

While we show this pathway predominantly in kidney, we believe it can be translated to other organs and diseases as well.

[Isermann Lab @beyondclotting]

Using a podocye specific TF deletion mice, we show that loss of TF or its interaction with IFNAR1 promotes IFN response genes and increased TF activity. This in turn regulates the immune homeostasis within kidney and promotes macrophage infiltration.

[Isermann Lab @beyondclotting]

We are very happy to share our recently published work in ⁦@ImmunityCP⁩ on: Tissue factor binds to and inhibits interferon-α receptor 1 signaling. We show that TF-IFNAR1 within kidney plays an important thrombo-inflammatory switch for IFN response https://t.co/LCghBknVKr

[Joanna Kalucka @JoannaKalucka]

Just a few days left to submit your abstract for #Lipid Meeting 2023 in Leipzig, Germany. Eagerly awaiting a deep dive into #metabolism, metabolic, and #cardiovascular diseases. Don't miss this valuable scientific exchange. 👉 https://t.co/VZVUBQti43

[Isermann Lab @beyondclotting]

We have a broad range of topics which will be covered which go beyond traditional roles of „lipids“ and „lipid metabolism“. Therefore please submit an abstract soon!

[Isermann Lab @beyondclotting]

Last few days left to submit an abstract for the Lipid Meeting 2023 in Leipzig, Germany for an excellent scientific exchange.

https://t.co/YpVam4GtvP