Bina Singh

captivated by macro-molecules for life...
PhD in Structural Biology. Postdoctoral Researcher at Umeå University

[Bina Singh @binasingh_7]

Excited to share the last publication from my PhD work in the latest FEBS issue: We show the positively charged C-terminal end of HadBC, a dehydratase involved in the Fatty acid synthase pathway-II of Mycobacterium tuberculosis #pdb #FEBSJournal

[The FEBS Journal @FEBSJournal]

📚 The C-terminal end of mycobacterial HadBC regulates AcpM interaction during the FAS-II pathway: a structural perspective

✒️ Amit K. Das et. al.
🔗 https://t.co/J0OBXK2gEW

[Structura Biotechnology @structurabio]

Looking for a deep dive into 2D classification in #cryoEM?

These recent guide pages cover practical aspects & parameter choices when running these jobs in #CryoSPARC, along with the theory behind expectation maximization: https://t.co/vpWLIlrBK3 and https://t.co/TKUYlvhruy

[Jake Smith @crying_EM]

After thousands of microscope hours and several years of painstaking optimisation, @glynnca93 and I are very excited to share our latest manuscript. We outline our approach to investigate the molecular organisation within hippocampus tissue using cryo-ET.

[Integrated Structural Biology @ISB_UmU]

We have a faboulus CryoNET meeting in Aarhus, LAC @lacarlsonlab on stage!

[Schuh Lab @SchuhLab]

Each month an #egg is ovulated from the #ovary, starting the journey of reproduction. But how does ovulation occur?🥚

Our latest work in @NatureCellBio led by @LastChrisThomas and @Tabea_Marx, describes the control of #ovulation using live imaging.

https://t.co/EYjwLfdAdy (1/7)

[Arthur Douillard @Ar_Douillard]

The Nobel prize website has a pretty well made 1-pager on how Alphafold works

[Carlson Laboratory @lacarlsonlab]

Hey #teamtomo, here's a cryoEM Rorschach test. What is this? Anyone without inside information, post your guess in the comments!

We hope to post the answer on biorxiv within a week. :)

[Olivier Schwartz Lab @Virus_Immunity]

Safe and effective in vivo delivery of DNA and RNA using proteolipid vehicles coated with the fusogenic FAST protein: @CellCellPress
https://t.co/YE4EVOKSbs

[Structura Biotechnology @structurabio]

1/ #CryoSPARC v4.6 is out! 🚀Up to 2.1x faster refinements and classification, a new job tree view that is scalable and performant on large #cryoEM projects, job groups, new cards and table view, automatic inspect picks, and more!
https://t.co/M3mLGtFPIq

[Himanshu Sharma @shrma_h]

Our work on the fascinating Microsporidia Polar tubes finds a place on the cover of @PLOSBiology latest issue. Check it out here https://t.co/pE7Qz66DQX

[Carlson Laboratory @lacarlsonlab]

A snapshot from Tuesday's successful PhD defence by @KasShankar. Excellent job - you deserved the title to💯%. Big congratulations on the PhD from the whole group!

[Bina Singh @binasingh_7]

An amazing opportunity to work with a cool PI 😊

[Bina Singh @binasingh_7]

Great opportunity to work with the talented and amazing @DahmaneSelma.

[selma dahmane @DahmaneSelma]

Hey hey, if you like cell biology, virology, and enjoy Swiss chocolate. Join me at @FMIscience by applying for the lab manager position👇👇😃

[Carlson Laboratory @lacarlsonlab]

Perhaps the coldest #cryoEM delivery every?

Umeå's EM facility, UCEM, received its Aquilos 2 FIB-SEM system today and the thermometer shows -29C. Kudos to the driver who delivered it from Brno!

@ISB_UmU @Ucmr_sweden @umeauniversity @thermosciEMSpec

[Pallabi Sengupta @PallabiSengupt8]

Lunchroom of our dept is dressed up in Christmas lights

[Jan Kosinski @jankosinski]

A new version of AlphaPulldown by @dingquan_yu. Includes experimental support for multimeric templates in AlphaFold by @DmitryMolo90428 and interface to crosslink-based modeling AlphaLink2 of @RappsilberLab
https://t.co/n6rIH9Soed

[Bina Singh @binasingh_7]

It’s really cool stuff. If anyone is interested in #virology #cryoET or #biochemistry. Do apply.

[Carlson Laboratory @lacarlsonlab]

RT appreciated:
We have an open #PhDposition. Join us in Umeå, 🇸🇪 to explore the mysteries of virus-infected cells using cryo-ET, biochemistry and cell biology.

Application deadline 17 December. More info: DM or read here:
https://t.co/bUNqsdxnTy

[Structura Biotechnology @structurabio]

1/ #CryoSPARC v4.4 is here! 🚀
Updates include tools to streamline repeat #cryoEM processing, reference based motion correction, orientation diagnostics, symmetry tools, improved 3DFlex, caching, data cleanup and more!
https://t.co/M3mLGtFPIq

[Science girl @sciencegirl]

During a solar eclipse, the gaps between leaves on trees act as multiple pinhole cameras,

and each gap projects its own crescent-shaped image of the eclipsed sun onto the ground.

📹gottigreen

[SBGrid: Structural Biology Software @SBGrid]

New Title Alert: CryoREAD is a computational tool using deep learning to automatically build full DNA/RNA atomic structure from cryo-EM map.

Read more here: https://t.co/RPknKOVjX4

#atomicstructure #cryo-EM #science

[selma dahmane @DahmaneSelma]

Absolutely great final talk by Friedrich Förster at #CryoNet!!! Now it’s time to make our way back to Umeå @binasingh_7 @lacarlsonlab. Huge thanks to the organizers in Stockholm.