Sad news, Tom Volk, a mycology icon and my former PI, has passed. He was an exceptional mentor, teacher, and master of the pun. I am grateful to have learned from him and keeping him, his family, and the UWL community in my heart tonight
https://t.co/H4itPDGrjt
Today marks the 9 year anniversary of my wife's diagnosis with type 1 diabetes! Years later she has taken >10k shots, had 4 different insulin pumps, tried 5 types of insulin, 3 GLP-agonists, had 3 pregnancies and has raised two amazing kids!! Love you Sam, you are amazing!!!
Patrick Finn gives an #OTS2022 update on the @moderna_tx PA program. Solid preclinical data and the start of a first phase1/2 clinical trial is encouraging. Patients show lower 3-HP levels on treatment. @OTSociety
@FakihH9#ots22@LauraSepplore chairs the genome and rna editing session on the last day of @OTSociety meeting. Kicking off with @moderna_tx Patrick Finn presenting on mRNA as medicine (as opposed to the mRNA covid vaccine this company makes as well).
Every Nobel prize season, I am boggled that anyone owns a phone that audibly rings in the middle of the night. They're going to need a new strategy for when Millennials start to win.
Chemically stabilized siRNAs that can specifically reduce mutant Huntingtin in vivo. The paper that took forever to publish is finally online @NatureComms@RTI_UMassChan@KhvorovaL https://t.co/p3hHdy5crK
Next #OTS2022 talk by Karyn ONeilabout centyrin conjugates which can deliver siRNAs to specific tissues. She shows that centyrin targeting CD71 conjugated to Gys1 specific siRNA can achieve muscle selective mRNA and protein inhibition. @OTSociety
@jwattsgroup showing data from the heroic attempt by multiple labs at @RTI_UMassChan to come up with a treatment for Covid19. They were able 2 identify lead compounds extremely early, Mar '20, but due to logistic problems arising from covid, couldnt keep pace w/ moderna & pfizer
#OTS2022@OTSociety Q&A panel of OTS founders. Truly great to hear the story of the OTS! Perhaps most interesting story was Mano's story of the dancing at the OTS parties. In addition to chemistry, its clear we could all learn about dancing from Mano
Ryszard Kole, winner of 2021 #OTS lifetime achievement award for pioneering work in exon skipping. His work lead to the Sarepta drug #Exondys51 &more
Pääbo's father, Sune Bergström, won the Nobel Prize in 1982 for his research on prostaglandins. This is the 8th time the prize has been awarded to the child of a previous winner.