Patty Carter

Microbiome research writer, attorney, & engineer sharing implications of microbiome on health & disease.
Find me mostly at Instagram or LinkedIn.

[Patty Carter @biome393]

Healthy Pregnancy Diet. Melody Trial is now recruiting. Women less than 27 wks pregnant and those planning pregnancy, some w Crohn's. You choose your normal diet, or the UMass IBD-AID diet. You don't need to live near the 2 labs doing this work! https://t.co/9zl1jc2nRF @biome393

[GI Nutrition Foundation @GI_NutritionFdn]

Do all dietary emulsifiers have the same impact on the gut❓

@JudithWellens, @vds_julie1, @JoaoPGSabino & colleagues' new findings in healthy people:

✅ An emulsifier-free diet may ⬇ cholesterol levels

✅ Following an emulsifier-free diet + 5 different dietary emulsifiers (one each time):

🔸No changes in gut microbiota diversity

🔸⬇ Short-chain fatty acids, especially in people who consume the food additive carboxymethyl cellulose

🔸No differences in:
👉 Intestinal inflammation (faecal calprotectin, C-reactive protein)
👉 Cholesterol levels

🔸Carragenan ⬆ permeability

💡 The impact of dietary emulsifiers on gut microbiota, intestinal inflammation, and permeability seems to be dependent on the emulsifier

As one food contains more than one emulsifier, it seems prudent to decrease the consumption of foods rich in emulsifiers for better gut health

@AGA_CGH

[Amy Proal, PhD @microbeminded2]

Our new review is out! We detail mechanisms by which the viral, bacterial, parasite, and other pathogens that infect humans over a lifetime accelerate features of aging: https://t.co/osEgxokKM7

[Patty Carter @biome393]

@IldikoMe This is such an interesting time. Many of the children I worked with are now through college, moving out of pediatrician GI offices, and moving into adult practices. All use diet w no to varying degrees of meds. These practices are seeing long term remission paradigm change😯

[Patty Carter @biome393]

@IldikoMe Thank you @IldikoMe for all you are doing. The work in this space is so important!!!

[Patty Carter @biome393]

There is so much truth here @IldikoMe! I remember feeling like in a fishbowl at every physician (and social) gathering when I began diet beginning in 2010 --- how is it even possible that was fourteen years ago!?! We've come a long way, but NOT nearly far enough. I stand with you

[Ildiko ☕️ @IldikoMe]

I’ll give you a rare personal n of 1 to make a really important point because the kids, teens, and young adults who struggle are why I continue to be here.

When her GI asked at a checkup this week how she would rank her therapeutic diet of 7+ years on a scale of 1 to 10, with 1 being ‘most disruptive and difficult’, and 10 being ‘not at all disruptive or difficult’, she gave it an “8 or 8.5”.

Perhaps it’s time to start listening to patients and parents about how to improve quality of life and outcomes via dietary therapies. Be inquisitive. Ask patients who are doing the best. We are the experts here.

Diet and lifestyle (sleep, exercise) are also critical pieces of psychological wellbeing. Teaching teens they have agency and that they are not chronically ill victims creates empathetic, mature, and resilient individuals.

Nothing improves quality of life more than early effective and persistent disease control. By focusing exclusively on immune-directed drugs, the incontrovertible evidence is that you all but guarantee that the vast majority of kids, teens, and young adults will live with active disease and symptoms, at least on and off, leading to a plethora of psychological struggles as listed below.

The current treatment paradigm serves absolutely everyone, except patients.

[Patty Carter @biome393]

@IldikoMe Spot on👇
➡️Higher-quality nutrition significantly delayed onset for both IBD and T2D
➡️Higher microbiota diversity delayed IBD onset
➡️The abundance of specific microbial genera was strongly associated w various biomedical & lifestyle factors in T2D & IBD
Diet matters👊

[GutMicrobiota Health @GMFHx]

Microbiome studies report low gut microbial richness and diversity in patients with ulcerative colitis.

Recent evidence reveals UC patients who achieve long-term remission show evidence of substantial recovery of the gut microbial ecosystem:

https://t.co/pxhzUzTpZC

[Patty Carter @biome393]

[2020 Lamas et al] #AhR Aryl hydrocarbon receptor ligand production by the gut microbiota is decreased in celiac disease leading to intestinal inflammation. Throw genes out the window? Lactobacilus to balance #Celiac disease. @Evinature_

[Patty Carter @biome393]

Full disclosure. I'm NOT well versed on Evinature @Evinatu. Prelim👉NOT imm suppression; AhR pathway with downstream IL-22 upregulation; regul barrier permeability & mucosal barrier regeneration. https://t.co/ewOIbBXQFX

#IBD toolbox #curcumin #EVINATURE

[Nir Salomon @NirSalomon3]

Honored to see CurQD presented at #AIBD2023 in the nutrition panel led by @gym99 from @CedarsSinaiMed, @IBDMD of @UChicagoGI, and @JamesLewisGIEpi of @penngihep, which included an in-depth exploration of the evidence for and uses of CurQD as an add-on to current treatment plans.

[Patty Carter @biome393]

Curcumin-QingDai vs placebo in UC👇
Clinical response 85.7% vs 30.7%
Clinical remission 50% vs 8%
50% decr calprotectin 46.4% vs 15.4%
Endoscopic improvement 75% vs 20%
Week 16 clinical response, remission & biomarker response: 93%, 80%, 40%
https://t.co/ewOIbBXQFX
@Evinature_

[Patty Carter @biome393]

@NTforIBD @kimbralyRD @BarbaraOlendzki @almaldonxx @IldikoMe @GKochharMD @SCKimIBDMD @nhaskeyRD

[Patty Carter @biome393]

Incredible visual for knowing HOW to eat every meal, whether you have #IBD or not! Essential 8 is the cornerstone of IBD-AID👉 see its food list, Essential 8, and more at https://t.co/6DunSTHdpR
#probiotics #prebiotics #HealthyEating #nutrition

[Patty Carter @biome393]

While the Medit Diet ISN'T SCD or IBD-AID (#IBD diets being used to induce remission), MANY of the tenets are the same. Understanding basics and foundation is a great place to start. Signup, a link for later listen will be provided if you can't make it. #nutrition #HealthyEating

[GI Nutrition Foundation @GI_NutritionFdn]

Sure to be a great presentation on the Mediterranean Diet in IBD by Natasha Haskey (RD, PhD), Deanna Gibson (Ph.D.), and Jennifer Bennett (B.Ed, M.Ed, CCC)! @nhaskeyRD

#IBD #Gitwitter #Crohns #UC #nutrition

[Patty Carter @biome393]

@nhaskeyRD @IldikoMe @SCKimIBDMD @almaldonxx @BarbaraOlendzki @AliArjomand @charlie_lees @GKochharMD @TennysonMD @DCharabaty

[Patty Carter @biome393]

Look at diets like SCD, IBD-AID. Crohns patient colonoscopy results last week (no meds, 2010 strict SCD, then 2016 added more microbiome supportive #IBD-AID & modified SCD foods)👉NO EVID OF CROHN'S DISEASE, NO SIGNS OF INFLAM, TOTALLY NORMAL Colono #ibddiet @NTforIBD @kimbralyRD

[Neera Gupta, MD, MAS @NeeraGuptaMD]

Take-Home Messages from 20 Years of Progress in Dietary Therapy of Inflammatory Bowel Disease:
https://t.co/u1rGnM0j2N
Figure: Paradoxes of the Role of #Diet & Nutritional Therapy in the Management of #IBD
@kgikas10 @VaioSvolos @PaedsRH @KGerasimidis

[Patty Carter @biome393]

2 worthwhile motos. Never stop moving and lifting! Don't slow down!

#muscle #StrengthTraining #bonehealth #healthylife #healthylifestyle #osteoporosis

[Jackson Fyfe, PhD @jacksonfyfe]

Muscle and bone are closely linked.

Age-related loss of muscle (sarcopenia) and bone (osteoporosis) are both independently related to loss of physical function and independence into older age.

Great review by @csmithAEP and colleagues showcasing the many links between muscle and bone and the need for treatment strategies to target both of these important tissues.

“Exercise is the primary evidence-based prevention strategy capable of simultaneously improving muscle and bone health.

Unfortunately, holistic treatment plans including exercise in conjunction with other allied health services to prevent or treat musculoskeletal disease remain underutilized.”

https://t.co/OMcSuCngik

[Fara Kaufman @justfara]

So, I spoke to people getting food at a food bank and here are some things I learned from those in need:
1. Everyone donates Kraft Mac and Cheese in the box. They can rarely use it because it needs milk and butter which is hard to get from regular food banks.
2. Boxed milk is a treasure, as kids need it for cereal which they also get a lot of.
3. Everyone donates pasta sauce and spaghetti noodles.
4. They cannot eat all the awesome canned veggies and soup unless you put a can opener in too or buy pop tops.
5. Oil is a luxury but needed for Rice a-Roni which they also get a lot of.
6. Spices or salt and pepper would be a real Christmas gift.
7. Tea bags and coffee make them feel like you care.
8. Sugar and flour are treats.
9. They fawn over fresh produce donated by farmers and grocery stores.
10. Seeds are cool in Spring and Summer because growing can be easy for some.
11. They rarely get fresh meat.
12. Tuna and crackers make a good lunch.
13. Hamburger Helper goes nowhere without ground beef.
14. They get lots of peanut butter and jelly but usually not sandwich bread.
15. Butter or margarine is nice too.
16. Eggs are a real commodity.
17. Cake mix and frosting makes it possible to make a child’s birthday cake.
18. Dishwashing detergent is very expensive and is always appreciated.
19. Feminine hygiene products are a luxury and women will cry over that.
20. Everyone loves Stove Top Stuffing.

In all the years I have donated food at the Holidays, I bought what I thought they wanted, but have never asked. I am glad I did. If you are helping a Family this Christmas, maybe this can help you tailor it more. It does for me!

[Patty Carter @biome393]

Vagus Nerve podcast. Stimulate vagus with electrical devices on the neck or ear, and some say, slow breathing, cold water on the face, etc can positively simulate vagus. Read more at 2023 https://t.co/iBN4D368PK Transcutaneous auricular vagus nerve stim attenuates IBD in kids...

[Prof. Kevin J. Tracey, MD @KevinJTraceyMD]

Great summary and important thoughtful discussion of the #vagus nerve and #inflammation as discussed by a global leader in inflammation, Luke O'Neill, Professor of Biochemistry and Immunology @TrinityCollege Dublin. @laoneill111 ! #arthritis #IBD
https://t.co/xvhTAkH7pH

[Patty Carter @biome393]

Putting the pieces together. How to prevent IBD.

[Aline Charabaty, MD, FACG, AGAF @DCharabaty]

#SPED2023 @ACTECCU @OPGEgastro @pancco_org

💭Provoking talk #DrKenCroitoru🇨🇦
Can we predict & prevent #IBD?

#GEM project: predictors of IBD
⬇️Intestinal barrier fct
🦠Microbiome
🧪Anti-microbial antibodies
🧬Proteinomic & metabolome signature

🔮Can #diet modify these factors?

[Patty Carter @biome393]

Hard to imagine in 2023, but there's still, only some to no nutrition training, for those studying as their organ of choice, the gut. #microbiome #guthealth

[Frontline Gastro @FrontGastro_BMJ]

20% of trainees with no exposure to Nutrition, over 60% with no or only some exposure to Nutrition. This is not advanced endoscopy or HPB, this is Nutrition. How and why has that been allowed to happen? What decisions have been made to improve or worsen this? @BSGTrainees