A longitudinal study finds that whereas clonal hematopoiesis confers an increased risk of #atherosclerosis, the reverse is not the case, arguing for a unidirectional effect of clonal hematopoiesis on atherosclerosis
https://t.co/ZhwDH9EBKv
🫀#Cardiología| La hematopoyesis clonal es identificada como un nuevo factor de riesgo cardiovascular por el @CNIC_CARDIO, siendo una causa directa de la aterosclerosis, según un estudio publicado en @NatureMedicine@escardio@blrneble
https://t.co/1uvUpc5AiB
And another paper online simultaneously with #ESCCongress! With Dr. Valentin Fuster and colleagues @CNIC_CARDIO, we clarify the relationship between clonal hematopoiesis and atherosclerosis. @NatureMedicine https://t.co/4bYVH9ZBzt More details ➡️ https://t.co/ob4nfA8fku
Our study led by @MariaAZuriaga@ZhiYu_ACGT & with @josejfuster uses murine & human genetic studies to infer that individuals with TET2 clonal hematopoiesis may derive potent CV risk-reduction with colchicine https://t.co/0qv02pCwtq @ESC_Journals
🟢Colchicine has been proposed to lower CV risk via NLRP3 inflammasome inhibition.
🟢TET2 clonal hematopoiesis has been proposed to raise CV risk via NLRP3 inflammasome activation.
👉The signal convergence validates both notions & provides a path for potentially using a low-cost available medicine for CV risk reduction in TET2 clonal hematopoiesis.
@buutrg@M_Mesbah_Uddin@NakaoTetsushi@abhinrl@mchonig #ESCCongress
🔬Un equipo del @CNIC_CARDIO liderado por @josejfuster y #ValentinFuster descubre un nuevo factor de riesgo cardiovascular, la hematopoyesis clonal, e identifica un fármaco para reducir sus efectos. Los trabajos en @NatureMedicine y #EHJ presentados en el #ESCCongress y revelan que la hematopoyesis clonal es una nueva causa de #aterosclerosis 🫀
#OpenAccess🔓Nature ➡️ https://t.co/CgnqOV6I8u /
EHJ ➡️ https://t.co/tlSPTvOhiR
#Salud #Ciencia #InvestigaciónCardiovascular
Exciting work by @josejfuster + team now out w/ #ESCCongress in @NatureMedicine
In PESA, CHIP 🩸🧬 at baseline ➡️ de novo athero
(incl DNMT3A, whose relevance to athero has been uncertain)
❗️ No association of subclinical athero w/ subsequent CHIP ❗️
https://t.co/KBnTUObXba
Exploring the chicken-or-egg dilemma between clonal hematopoiesis and atherosclerosis. Our latest study, published today in @NatureMedicine (https://t.co/S26bV9zs7N), addresses this critical question. Check out the thread below ⬇️
📌 Will you be at #ESCCongress in London this weekend? If so, don’t miss the presentation of @josejfuster ‘Clonal haematopoiesis and cardiovascular diseases’ at the framework of the Symposium Emerging risk factors for cardiovascular diseases.
📅 August 30
⏰ 16:15 PM BST
📍 San Marino
➡️https://t.co/hoWCSub3eN
#CardioTwitter #laSECtelleva #cardiovasculardisease
We are already over halfway into the #dcawintermeeting24 in Norefjell, Norway ❄️
This year's topic is "Ageing and cardiovascular disease" 👵🏾👴🏼🫀
Stay tuned for more highlights from the meeting! 📸✨
Exploring the fascinating interplay between sauna sessions, exercise, and vascular health with the participants at @DCAcademyDK. Testing the macro and microvasculature response, observing the metaboreflex, and monitoring leg blood flow dynamics. 🔍💪 #VascularHealth
¡Feliz Día Internacional de la Mujer y la Niña en la Ciencia🧪! La implicación de empresas y administraciones en la orientación es clave para que las estudiantes puedan conocer perspectivas profesionales en la ciencia y descubrir vocaciones🙌. Inspírate en #EmpresasQueInspiran👇
Yankee Swap, lunch and a Escape Room, great way to celebrate together a year of hard work (and some fun 😎)! Happy Holidays from our lab at @CNIC_CARDIO!
Thanks to the Speakers team, we have a wide panel of wonderful speakers gathered for us to enjoy and learn from 🗣️
They are Ana Rodriguez, Beatriz López, Jesus Martinez, Laura Lalaguna, Maria Linarejos Vera, David Del Rio, Jorge Mínguez, Carlos Cerón and Anabel Diaz-Guerra
@miriam_diezd and @blrneble from @josejfuster group at @CNIC_CARDIO presented their work on somatic mutations, clonal hematopoiesis and subclinical atherosclerosis at the IV Interdisciplinary Human Genetics Congress last week, congratulations!
Gracias a todo el equipo de #CardioGuía!Trabajar con vosotros ha sido una gran experiencia..gracias al apoyo de @CNIC_CARDIO y gracias a todos los participantes! hasta la proxima!Sigue la #SemanaDeLaCiencia en el CNIC: https://t.co/zsxXn99KcC no te la pierdas!