Cognitive dysfunction and learning and memory impairment are found to be associated with altered expression of MCTs (Leroy et al., 2011; Lauritzen et al., 2012; Perez-Escuredo et al., 2016). Recent studies have also demonstrated that learning and memory deficits are observed in rats following inhibition of hippocampal MCT1 and MCT4 (Suzuki et al., 2011; Sun et al., 2018; Descalzi et al., 2019).
Saskatchewan scientists screened the entire human genome and found four approved drugs: donepezil, dihydroergocristine, trametinib, and sorafenib that block SARS-CoV-2.
Three also stopped common cold coronaviruses, suggesting broad antiviral potential.
https://t.co/kSmU0SuWuJ
Der Verlust staatlicher Souveränität im Neoliberalismus ist kein Naturgesetz, sondern eine politische Entscheidung. Wie können wir die Kontrolle über Markt und Kapital zurückgewinnen?
#EDITIONMAKROSKOP#Kapital#Markt#Staat#Neoliberalismus#Demokratie
https://t.co/zGb1XT3PPs
Since I’m a neuropathologist, I’ll put my two cents into this MND discussion.
SARS-CoV-2 isn’t just a respiratory virus. Emerging evidence shows it can infect human motor neurons. Could this link to motor neuron disease (MND)?
Let’s break down the neuropathology. 🧵
COVID was never just a respiratory virus - it’s a systemic one.
A pathogen that rewires immunity, disrupts mitochondria, and infiltrates the nervous system -
sharing striking parallels with HIV.
Here’s part of what we already know🧵
University of Virginia researchers found that a protein called TCF4 helps lung macrophages renew and repair tissue after flu or COVID infection.
Boosting TCF4 restored recovery and reduced lung fibrosis, suggesting a new path to treat long COVID.
https://t.co/7AHRhBD2kv
ANTARCTIC ICE SHEET GOING THE WAY OF GREENLAND
The vast Antarctic ice sheet is not as stable as thought
The same processes speeding up Greenland destabilization are happening to Antarctic. Sea level rise will be faster.
Another big bad climate change surprise
3 Oct. 2025 Greenlandification of Antarctica,
Mottram, Nature Geoscience
#icesheet #climatechange #sealevelrise #globalwarming
Dysautonomia Awareness Month: Mast cell activation syndrome (MCAS), a condition that can co-occur with dysautonomia and ME/CFS, involves mast cells over-producing chemicals like histamine. It has many triggers, such as stress, caffeine, and certain foods https://t.co/y4tCvprcd2
Wer an #MECFS leidet, ist schwer erkrankt.
Dies als bloße "Erschöpfung" darzustellen, wird weder dem Kernmerkmal #PEM noch der allgemeinen Schwere einer Erkrankung an #MECFS gerecht und führt in die Irre.
Bagatellisierungen dieser Art haben jahrzehntelange Ignoranz ermöglicht.
Somebody asked me yesterday for a list of differential diagnoses for ME/CFS. Here's a second chart.
As some have argued, people can have these and still have ME/CFS
#MyalgicEncephalomyelitis#ChronicFatigueSyndrome
1/
BREAKING NEWS!
In June 2025, the American Medical Association (AMA) approved and adopted a FRAGRANCE REGULATION into its official policy database:
FRAGRANCE REGULATION H-135.902
The AMA policy states:
“Our AMA encourages health care facilities, government agencies, and nonprofit organizations to adopt and promote fragrance-free policies...”
The American Medical Association’s new policy similarly states that “...some environmental exposures may have the potential to SUBSTANTIALLY LIMIT MAJOR LIFE ACTIVITIES of an individual with fragrance sensitivity…”
Accordingly, the new AMA policy meets the ADA’s definition of a disability.
The adverse health effects of fragrances are now more widely recognized.
AMA: Fragrance Regulation H-135.902
https://t.co/X8LCyW2ldG
„Lange Zeit galt in der Immunologie die Ansicht, das Immunsystem müsse hin und wieder getestet werden, um stark zu bleiben. Das ist eine altmodische Vorstellung. Ihr Körper nimmt Schaden mit jeder [COVID]-Infektion, die er überlebt.“ - David Putrino @PutrinoLab
Das #ZDF Frontal zeigt: „Phantomdiagnosen in der #ePA sind kein Zufall.“:
Die Psychosomatische Grundversorgung,
die F-Diagnosen systematisch fördert, sei hierbei wohl Hintergrund.
Für #MECFS#PEM Betroffene bedeutet das reale gesundheitliche Schäden – v.a. durch Fehlbehandlungen.
“Children and teenagers are twice as likely to develop #LongCovid after a second coronavirus infection as after an initial infection, a large new study has found.
The study, of nearly a half-million people under 21, published Tuesday in Lancet Infectious Diseases”
@FatigueMe92484@scott_scientist The time I developed "CFS ", most people like me described the onset by 3 factors:
The infect, distress, and environmental disruption, as makeover, fumes, mold.
I post environmental studies because I believe they are partially responsible for ME. I have traced all of my periods of coming out of "remission" and a few of them were caused by environmental toxins. While pathogens are the primary source they are not the only ones and include mechanical injury and emotional trauma. The biological activation of the stress response is very similar with each of these stressors!
Gleich zwei Sozialgerichte urteilen, Versorgungsämter dürfen #LongCovid und #MECFS nicht als psychische Erkrankung einstufen - Betroffenen wurde die Tür zur Anerkennung einer Schwerbehinderung geöffnet https://t.co/4XOerXAxrB @riffreporter