@MatteoPerino_@RothbartLab@GryderArt you may not overcome everything in cut&run, but if you can measure DNA mass coming out of cells you can at least project that mass as a crude quantification. sorry I'm 3 years late, mass projection is vaguely discussed here: https://t.co/WT78C8vvXL
@arjunrajlab worth mentioning quantitative chip-seq can be defined without spike-ins via the same basis as the familiar Wiseman isotherm, common to techniques like ITC where binding constants are measured (sans spike-ins)
https://t.co/WT78C8uY8d
https://t.co/w5YrkHNfl8
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@tangming2005 @biobenkj @scarsoncallahan I can't promise to have proof read all of this, but I have tried to make an interactive introduction of the model. I hope it proves helpful in sharing what has indeed become a 'crusade' :
https://t.co/y6cYHeA8yd
notation matches recent version of the paper.