Big day for the David lab! 🎉 Our @MolecularCell paper is out today- huge congrats to first authors @IfeAkano & Jake Hebert for leading this beautiful study uncovering SMARCA3 as a novel H3 E3 ligase that shapes heterochromatin regulation in colorectal cancer 🤩
A person’s lifetime risk for #cancer may begin before they are even born, reports a paradigm-shifting study by Van Andel Institute scientists published in @NatureCancer. @PospisilikJ@Bi0lilla https://t.co/rv8rNOBA7U
Thrilled to share the results @Cancer_Cell of years of hard work to develop classifiers for all major TCGA cancer subtypes, enabling assessment of differential drug response among cancer subtypes in clinical trials. https://t.co/wRSqdhY31e
We have postdoc positions open to study epigenetic mechanisms contributing to resistance to chemo+immuno in TNBC, and projects related to epigenetic determinants of neurodevelopmental disorders. Feel free to reach out to me here/via email. Please like and repost!
Congratulations to Van Andel Institute’s Dr. Peter Jones, VAI and @HopkinsKimmel's Dr. Stephen Baylin, and @HopkinsMedicine's Dr. Andrew Feinberg, who will receive the Harvey Prize for their groundbreaking work in cancer epigenetics! Read more: https://t.co/TV67Qlr4JM
This preprint is now published with some key additions guided by an excellent review process @NAR_Open. Also grateful to our collaborators for helping progress this one across the finish line! @suscla1@qianthefirst@Yael_David__@zhouwanding and others!
https://t.co/OX85ljomqn
Online Now: DNA hypomethylation promotes UHRF1-and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin states https://t.co/xX336PoECe
Congratulations to the authors @RothbartLab, shows the role of UHRF1 in the redistribution of H3K9me3 following DNA hypomethylation, a lingering question in the field and may have implications for the field of aging.
https://t.co/JN6hzPllkN
Two new papers from the lab to end the year! Will be posting about them both at the new place in the coming weeks. @rothbartlab.bsky.social
Come join us - it’s great! #SciCommBackAgain
@helin_kristian@helink Also made the move. It’s becoming reminiscent of the good ‘old’ days of ScienceTwitter over there. Come join us! @rothbartlab.bsky.social
Time to move. See you all on Bluesky: @helink.bsky.social
Let's work on getting our respective institutions and our colleagues to move as well. There is an exponential increase in members on Bluesky!!
https://t.co/KZKb8MYzve
If you are interested in a faculty position in the heart of metabolism, at one of strongest and most supportive institutes focused on metabolism, epigenetics, neurodegeneration and more, VAI is recruiting at all levels! https://t.co/EwTTupFw64