Now enrolling through @ALLIANCE_org - STRIKE! (A032201) exploring the role of Tivozanib with pembrolizumab following resection of ccRCC - check out our TIP at #GU26@ASCO@DanaFarber_GU https://t.co/ThH1RX9Dkj
Team America 🇺🇸 🇨🇦 have their educational video - with novel soundtrack - for Uromigos cup 🏆. Eurasia is winning. ♥️ =points. Surely it’s time for a win for the Americas. #UromigosLive@OncoAlert@montypal
At @AUC3 2024, everyone agreed - it is time to retire the prognostic tools as predictive biomarkers and focus on biology. Look forward to discussing this and more at $UromigosLive 2025 @Uromigos@OncoAlert
https://t.co/imTCKXoWVC
The UromigosLive 2025 meeting presents #UromigosShorts videos on GU Oncology topics. The videos with the most views win a prize at #UromigosLive November 7-8th in Nashville, TN. Below, Dr. Bradley MCGreggor discusses: Favorable Risk RCC.
As we decide how to treat a patient with fav risk RCC - why are we using clinical prognostic tools to predict benefit of one therapy over another? @DrChoueiri@montypal@DanaFarber_GU https://t.co/imTCKXoWVC
The UromigosLive 2025 meeting presents #UromigosShorts videos on GU Oncology topics. The videos with the most views win a prize at #UromigosLive November 7-8th in Nashville, TN. Below, Dr. Bradley MCGreggor discusses: Favorable Risk RCC.
@crisbergerot@ASCO Starting with tivozanib 1.34 mg D1-21 every 28 days important - in later line setting need to optimize tki dose adjusting as neeed for toxicities to get greatest benefit
It was a great run - join us tomorrow am at 545 in Marriott Marquis lobby for all run along the Embarcadero to finish off #GU25@ASCO@maughanonc@montypal
Thanks @PBarataMD for highlighting CAN-I! Poster up at #ESMO24; with extended followup Cabo/nivo/ipi with ORR 21% in RCC with divergent histologies though significant toxicity. Work ongoing correlating pdl1 and genomics with response @DrChoueiri@VincentWenxinXu@DanaFarber_GU
Up now - DAD update for #ESMO24! With 22 month followup SG+EV for 2L+ active with no new toxicity signals. ORR 70% with 4 CR; 6 patients with ongoing response - median DOR 10 months (range 3-33+). DADIO coming soon! @OncoBellmunt@DrChoueiri@DanaFarber_GU
NKT2152 an oral hf2 inhibitor with half life of 38 days has activity in heavily treated ccRCC with ORR 20% (26% with longer followup) with no unexpected toxicity. Trials ongoing exploring dose and activity following belzutifan - open @DanaFarber_GU@DrChoueiri
Nivo/ipi improves 12 month overall survival rate vs SOC with ORR 33%; responses seen in 7 patients (25% ORR) with chromophobe RCC. PDL1 may be a predictive biomarker #ESMO2024@DrChoueiri@lalaniMD
First presentation of @myESMO - addition of nivoluamb to tiovzanib does not improve outcomes following progression on immunotherapy; tivozanib with encouraging PFS of over 9 months when used second line - full data in @TheLancet@DrChoueiri@lalaniMD@DanaFarber_GU