Graham Brady

Liver doc & researcher @ Univ of Michigan, husband, dad to 3 cool kids. Views are my own, RTs aren't endorsements, etc.

[Llorente Lab @CristiLlorente]

Looking forward to The Liver Link at DDW!
Will you be joining? 📕📖
Sessions will explore liver–gut–immune–brain networks, mechanisms driving MASLD, MASH, ALD, and cholestatic disorders, and cutting-edge advances in multi-omics, microbiome, and immunology.
https://t.co/hWFYzikKEa

[Jason Shepherd @JasonSynaptic]

“due to recent NIH actions, more than 4 in 5 early career researchers are considering leaving academia or relocating outside the US. When I directly pressed Bhattacharya about this exodus during our meeting, he said that if researchers did not like the way things are in the US /1

[Sobia Laique MD @SNLaiqueMD]

Dr. Shreya Sengupta was a gifted clinician, rising health services researcher, and fierce advocate for the most vulnerable. Her work transformed ALD care and advanced equity in hepatology.

Thank you @AASLDtweets for honoring her legacy. Donate: https://t.co/H0ZGTAaJyf

[Michigan Football @UMichFootball]

'TIS THE SEASON! 〽️

[Graham Brady @brady_gf]

I am not leaving this hellsite, but I am now also on Bluesky:

@brady-g.bsky.social

[Graham Brady @brady_gf]

@CterminiPhD lol. Sadly I don’t think this is too far off

[Graham Brady @brady_gf]

@CterminiPhD Ugh. Yeah I’m sorry. My impression is that the staff have a pretty clear idea of what, and whom, they want to fund…and quite a bit of power to do so, or not

[Graham Brady @brady_gf]

@CterminiPhD Sorry to hear this. Very tough. I wonder- was this an NIGMS MIRA?

[Kapil Upadhyay @Kapil_Upadhya]

🌟 I am thrilled to share that I have been awarded the Outstanding Postdoctoral Fellow Award at the @UMich ! 🎉 This recognition honors postdoctoral fellows who excel in research, teaching, mentoring, service, and leadership.

[Michigan Football @UMichFootball]

IT’S GREAT TO BE A MICHIGAN WOLVERINE!

#GoBlue

[Graham Brady @brady_gf]

Our article is now available full open access (through Oct 29) here:

https://t.co/UUoGMlhwd5

[U-M Department of Internal Medicine @UMIntMed]

Dr. Vincent Chen, Dr. Elizabeth Speliotes, Dr. Graham Brady (@brady_gf), and team discuss a common variant that alters SUN1 degradation and its association with hepatic steatosis and metabolic traits in multiple cohorts.

Read more below!
https://t.co/ff2myniUSy

[U-M Department of Internal Medicine @UMIntMed]

Dr. Vincent Chen, Dr. Elizabeth Speliotes, Dr. Graham Brady (@brady_gf), and team discuss a common variant that alters SUN1 degradation and its association with hepatic steatosis and metabolic traits in multiple cohorts.

Read more below!
https://t.co/ff2myniUSy

[Graham Brady @brady_gf]

First-author papers coming fast and furious from @Kapil_Upadhya

[AJP-Gastrointestinal and Liver Physiology @ajpgi]

👉New in #ajpgi! "Hepatocyte-specific loss of LAP2α protects against diet-induced hepatic steatosis, #steatohepatitis, and fibrosis in male mice" by Kapil K. Upadhyay (@Kapil_Upadhya) et al.

🖱https://t.co/Eq3DEB3lRo

@brady_gf @umichmedicine @RutgersCABM

[AJP-Gastrointestinal and Liver Physiology @ajpgi]

👉New in #ajpgi! "Hepatocyte-specific loss of LAP2α protects against diet-induced hepatic steatosis, #steatohepatitis, and fibrosis in male mice" by Kapil K. Upadhyay (@Kapil_Upadhya) et al.

🖱https://t.co/Eq3DEB3lRo

@brady_gf @umichmedicine @RutgersCABM

[Graham Brady @brady_gf]

@NIDDKgov @liverUSA @UMIntMed @MichiganLiver Alternative full-text link:
https://t.co/Dy9EZMfk0S

[Graham Brady @brady_gf]

Now online: led by first author @Kapil_Upadhya, with Liz Speliotes, Vince Chen, & others – we found a common coding variant in the gene encoding the nuclear envelope protein SUN1 associated with hepatic steatosis & MASLD-related traits in multiple cohorts
https://t.co/SHJARIvmeg

[Graham Brady @brady_gf]

When expressed in cells, this variant increased SUN1’s proteasomal degradation, blunted insulin signaling, and increased lipid droplet accumulation, supporting a potentially causal role in MASLD. Funded by @NIDDKgov & @liverUSA; thanks also to @UMIntMed and @MichiganLiver

[Robert Fontana @RobertFontanaMD]

SEEKING: TRANSPLANT HEP FELLOW JULY 2023
Interested to join a winning team? Available 4th year TXP HEP fellow slot @umichmedicine. Great cases, people, teaching & mentorship https://t.co/fFLl0drdJ8
#GoBlue #LiverTwitter #GITwitter @MichiganLiver

[Graham Brady @brady_gf]

@MichiganLiver @Kapil_Upadhya Thanks for boosting this nice study and supporting @Kapil_Upadhya (especially since I had to leave town). Should note that he crushed his talk on Saturday as well!

[Graham Brady @brady_gf]

@Clot1 @UMich Congrats, that is fantastic!