Amir Meghdadi

Computational Neuroscience | Neurotechnology and Quantitative EEG in Clinical Research | Director of Research at Advanced Brain Monitoring 🧠

[Amir Meghdadi @brainsignals]

(1/n) 🧵Publication alert: Our latest work on #EEG #Biomarkers in MCI and #Alzheimers disease is published in @PLOSONE. In this thread, I will highlight the main findings. Check out the open access link here: https://t.co/34wex8gbWM

[Amir Meghdadi @brainsignals]

Presenting today at #sobp2026, poster number 123, the effect of Ketamine on auditory habituation in recurrent depression. @SOBP

[Amir Meghdadi @brainsignals]

@CTADconference
Visit poster P333 today to learn about how we use #EEG and #ERP as biomarkers of #cognitive decline in #Alzheimers disease.

[Amir Meghdadi @brainsignals]

Face perception relies on neural mechanisms that rapidly extract identity and emotion. In major depressive disorder (MDD), these mechanisms may be altered, showing heightened sensitivity and biased processing toward emotional faces. #Sfn2025 #SfN25

[Amir Meghdadi @brainsignals]

#Ketamine’s therapeutic effects in patients with recurrent #depression and the associated #EEG and #ERP changes. #Sfn2025
https://t.co/CKOUWkDr52

[Amir Meghdadi @brainsignals]

#Ketamine’s therapeutic effects in patients with recurrent #depression and the associated #EEG and #ERP changes. #Sfn2025
https://t.co/CKOUWkDr52

[Amir Meghdadi @brainsignals]

At #Parkinson's Empowerment Day with my colleagues at ABM. We invited attendees to learn about participation in our ongoing research focused on identifying #EEG #biomarkers for #neurodegenerative diseases such as #Parkinsons and #Alzheimers.

[Amir Meghdadi @brainsignals]

Advanced Brain Monitoring secures #NIH funding to develop EEG/ERP biomarkers of cognitive impairment in Long COVID. 🧠
I am grateful to @NIH for supporting this work. #EEG #LongCovid #NeuroCovid
https://t.co/1CrNXdEaQS

[Amir Meghdadi @brainsignals]

@melnykowycz @IDUNTech How well does it work though? Have you done experiments to measure its effectiveness?

[Amir Meghdadi @brainsignals]

@DaniBeckman Amazing picture. Can you please elaborate a bit more on how the picture shows the reaction of Astrocytes? Does the picture shows astrocytes only and not neurons? Are they breaking up the plaques?

[Amir Meghdadi @brainsignals]

@cbarbermd @DaniBeckman Please be cautious, AI model are often full of inaccuracies if asked about specific scientific topics. A “quick GPT search” is great to provide some directions for researching the topics, but the responses should not be trusted as facts.

[Amir Meghdadi @brainsignals]

@francoisfleuret Except, that’s usually not how it works at least in “science” topics. First you indicate what you intend to do and the expert approve it. Then you complete it (and consult with the said expert along the way), and finally the experts approve the work. The reason: statistics

[Amir Meghdadi @brainsignals]

@DrNeuroChic @Clarivate Invest half an hour on Zotero (free) and you will never come back to Endnote. Remember to install the plugin for your browser. Surf the web and cite at the same time!

[Amir Meghdadi @brainsignals]

@DaniBeckman More explanation would be great. Is this raptured vessel? What are the pink dots? Amazing picture.

[Amir Meghdadi @brainsignals]

@NTFabiano To me, this question, rather than questioning depression as a diagnosis, posed the possibly philosophical question of “what do we really mean by diagnosis?”. Especially when there is no evidentiary biological pathology 🤔

[Nicholas Fabiano, MD @NTFabiano]

Researchers paid $8.968 billion for their findings to be freely accessible.

🧵1/10

[Amir Meghdadi @brainsignals]

@AndrewHires What I would really want to know is that how much of the quality of its response depends on the last part of the prompt: “make sure you do a good job”! It would be another level fascinating if we need to request, remind(?), negotiate (?) to an AI to do a better job!

[Amir Meghdadi @brainsignals]

Very interesting but let’s not forget that “correct diagnosis” here is the ground truth provided by us, not AI. In other words, this could just mean that the collective knowledge of many doctors (AI knowledge base) outperforms the average of the performance of the said doctors.

[Nicholas Fabiano, MD @NTFabiano]

AI outperformed doctors on reasoning tasks.

Doctor = 30% correct diagnosis
AI = 80% correct diagnosis

🧵1/8

[Amir Meghdadi @brainsignals]

For insights into our current findings in this ongoing project, explore our recent publications:
https://t.co/xtEvXwQhwF
https://t.co/DOt1iWw7Rb

[Amir Meghdadi @brainsignals]

1/n: Our paper on #EEG #biomarkers of #Alzheimers #dementia and #MCI is now published in @PLOSONE. Supported by @NIH, this study demonstrates EEG changes in #CognitiveDecline in contrast to normal #aging. @AcademicEEG,#NeuropsychTwitter,@ISTAART
https://t.co/J7SFsyZmVJ

[Amir Meghdadi @brainsignals]

Advanced Brain Monitoring, exhibiting at the #Parkinson's Association of San Diego's Empowerment Day, empowering patients to live their best lives with #Parkinson’s Disease, while showcasing the latest advancements in treatment and disease management.

[Amir Meghdadi @brainsignals]

We demonstrated our non-invasive #EEG technology for assessment of #brain health, inviting attendees to participate in our @NIHAging supported study of #EEG #biomarkers for #neurodegenerative diseases like #Parkinson’s and Alzheimer's.

[Amir Meghdadi @brainsignals]

@fabnascimen @KNascimenski @SBeniczky @EpiDisorders Can someone send me the full text, please. Thank you!