Jesse🇮🇱🇺🇦

VP Eng @GrowthLoop 🔁 Rational optimist & classic liberal 📈 Millennial boy 🖤 just. fucking. build.

[Eric Lombardi (EricForOLP.ca) 🇨🇦🚀 @EricDLombardi]

This entire story is just ghastly and a horrifying indictment of Canada’s/Ontario’s healthcare bureaucracy.

Simply put, nobody should have to go to court to get access to lifesaving care, yet that is exactly what happened to Alex.

It’s equally appalling that the Health Minister, @SylviaJonesMPP ghosted a father simply fighting for their life and future.

Many people involved in this saga need to do some reflection on how they let procedural technicalities be prioritized over one of our citizens lives.

https://t.co/zMUi1z8QBb

[DHH @dhh]

There's nothing kind about letting good people live in a fantasy world that no longer exists. You have to tell them, even if it hurts. Because the sooner they accept reality, the sooner they can adapt to the future.

[DHH @dhh]

It's pencils down, people. Writing code by hand is no longer an economically viable skill for most programmers at most companies. But the future of making software has never been brighter. Don't you dare black pill this beautiful moment! https://t.co/qaCgfmkW0u

[Anthropic @AnthropicAI]

Claude has discovered a previously unknown enzyme system hidden in the DNA of bacteriophages. Beside the enzyme’s gene sits a long array of repeating DNA—a structure that looks somewhat similar to CRISPR.

We don’t yet understand what this system does, but only a handful of known systems share its features, and all of them are able to cut, copy, and paste DNA. Historically, the discovery of such programmable systems has helped revolutionize medicine. CRISPR, for instance, is now the foundation of genetic medicines. But it will take much more work to learn what this system does, and whether it can be put to similar use.

Read more: https://t.co/RuEosScSMb

[Christian Elton @christianelton]

The gap between major model releases keeps shrinking.

2023: once every 73 days
2026 (so far): once every 18 days 🤯

[Slava Akhmechet @spakhm]

Long range career advice. (Won't help you get a job tomorrow, this is a ~10-20 year thing)

You want to run two processes. Your main loop:

1. Knock on doors, many outside your league, and get yourself in a room with the most competent people who will have you.
2. Work your ass off to be reliably useful to them. Like, really, _really_ hard. However hard you think you're working to be reliably useful, work ten times harder. Also, be cheerful.
3. Every once in a while pop your head out and go to step 1.

Your background loop: look around for weird asymmetric opportunities. A startup to found/join, a project to hack on, an angel investment into a friend's company, whatever. When your heart sings, jump on it. (You will fail a lot but that's fine so long as you handle failure well, I'll cover that in another post)

In exchange for working really hard you get two things. First, knowledge/experience-- you learn a ton. Second, relationships-- ppl will remember how great it was to work with you. Knowledge and relationships with competent ppl create crazy asymmetric opportunities. You then jump on those. (There is a lot of twitter slop about compounding, well this is what career compounding looks like.)

---

Now some failure modes. Do _not_ do this:

"I deserve much better than this company/role, I'm just going to begrudgingly collect a paycheck" --> first, you deserve what the market clears and that's that. Second, if you act this way you'll only hurt yourself. Your colleagues will remember you as a grouch and it will wreck the compounding loop. Third, it's a very unpleasant state to be in, and you should choose not to be in it.

"But I work at Home Depot, what's there to compound?" --> that's extremely shortsighted. Maybe you do a super good job helping a customer who then has an open spot and remembers you. Maybe your store manager becomes a regional manager and calls you. Maybe years down the line your quiet peer is looking for a partner to start their own store. Maybe none of this happens, but it doesn't matter because empirically ppl who try hard to be useful wherever they are tend to do great, and people who don't, don't. (Home Depot is a metaphor, obviously)

"I hate this place, I quit! And anyway they're a faceless corporation that will lay me off any time." --> don't do that. The company may be a faceless corporation, but your colleagues are not faceless. They bet on you, hopefully you did a great job, and now they depend on you. Leaving is never easy, but do it in a way that respects the trust ppl put in you.

"Everyone around me is an idiot, I hate this!" --> maybe they are, or maybe you're not ready and some day will discover you were wrong about this. In any case you can learn from everyone and everything. So do that and be useful, don't break the compounding loop because opportunities will surprise you and things are often not what they seem.

“_I_ should have been promoted not that other guy/why is my manager layering me, screw this!” --> every time that happened i eventually understood I deserved it, you probably do too. Don’t hold grudges, do your best to figure out how to learn from this and move on, it will make sense eventually.

P.S. it helps if you’re a little talented.

[Jason Kenney 🇨🇦🇺🇦🇮🇱 @jkenney]

The guy who broke BC's economy is now breaking the law in a sneaky and cynical attack on democracy.

He's forcing an election two years ahead of the legislated date purely to exploit a pending leadership change in the main opposition party. It's the most breathtakingly cynical move I have ever seen in Canadian politics.

Hopefully BC voters will demonstrate that they refuse to be manipulated by punishing Eby and his incompetent, ideologically obsessed government.

[OpenAI @OpenAI]

Please welcome GPT-6 Sol and GPT-6 Luna to the GPT-6 universe.

GPT-6 Sol and Luna build on the advances behind GPT-6 Astra, bringing much of its strengths into faster and more affordable models to support work at scale.

We’ve also made caching and inference more efficient, and we’re passing the savings directly to you: 50% lower API prices for Sol and Luna compared with GPT‑5.6 promotional pricing.

[Brianna Wu @BriannaWu]

I’m a Democrat. But I really do understand now why the right was so upset about woke politics.

Because so much of the left can no longer explain why they hold a policy position and argue for it. They can only attack you and try to destroy your reputation.

Israel is a perfect example. There is objectively no genocide. There was no mass starvation. There were not mass numbers of children being killed. We now know the casualty numbers were false, and an overwhelming number of the people killed were militants from Hamas and Palestinian Islamic Jihad.

But try pointing any of that out. They don’t argue with you. They just scream louder and attack your reputation.

The non-binary issue is an even stronger example for me.

I have a very specific objection to the non-binary political project. If you expand the definition of transgender to include a huge number of people claiming the label through self-ID, with no medicalization whatsoever, you destroy the legal basis for defending my civil rights.

This is not theoretical. This is very literally part of why we lost a recent Supreme Court case and why states can now take away medication I cannot live without.

And you could write the response to this on autopilot.

Brianna Wu is a pick-me. The leopards will eat her face. She just wants to be one of the good ones. Blah, blah, blah.

No. I don’t want to be one of the good ones. I want public policy that is legally defensible for people like me.

And to be clear, the right does the exact same thing. They destroy Republican politicians who refuse to say Trump won the 2020 election. That is a far more serious and dangerous example.

America needs adults who can talk honestly about our national security strategy. We need transgender policy with much higher standards for medicalization because teenage girls are being permanently harmed by testosterone.

And we need a smarter response to people who raise these concerns than, “Shut up, monster.”

[Brianna Wu @BriannaWu]

Kind of love Demi Lovato’s response to people trying to drag her into free Palestine. “I’m a singer. I don’t have an opinion on Middle East conflicts.”

[@levelsio @levelsio]

Same with this article from yesterday

Gay acceptance is now rapidly dropping in the Netherlands

The real reason is Middle Eastern and North African (MENA) immigrants are extremely against homosexuality

But media isn't allowed or won't ever write that

It's ironic that the gay acceptance we fought for for decades in the Netherlands is being destroyed by progressive policies that keep continously importing low quality immigrants from cultures that are completely opposed to us

[Lachlan Phillips exo/acc 👾 @bitcloud]

They don't want to cancel Ed Sheeran.

They want to ensure that no artist feels safe expressing unapproved opinions on any topic.

It's a narrative capture. Textbook Marxism.

[tobi lutke @tobi]

@MorningBrew - definitely use it
- use it well

Too complex a set of instructions for various people around here it seems

[Uncle Bob Martin @unclebobmartin]

Read this. Read all of it. And then draw your own conclusion. My conclusion: he’s right on.

[Megatron @Megatron_ron]

BREAKING: 🇺🇸 All U.S. embassies in the Middle East have issued security alerts for their citizens, including Lebanon, Israel, Jordan, Iraq, UAE, Saudi Arabia, Bahrain, Qatar, Kuwait, and Oman

President Trump is urgently departing from Camp David to the White House, arriving tonight instead of tomorrow.

[Kosher @koshercockney]

I will say keep saying it.

There was never a Genocide or Famine in Gaza.

[Dumbass Photoshop @DumbassPhotoshp]

🖕🏽🇵🇸💩

[MrBeastClips @BeastWorldClips]

MrBeast is such a real one for calling this out 🔥

[Billy Talliwagger @talliwagger]

If Canada had built Energy East and Keystone XL we would have been bringing in $277 million per day or about $99 billion annually in additional revenue at current oil prices.

How do we blame Trump for this staggering failure?

[Kareem Rifai 🌐 @KareemRifai]

Rape of girls as young as 4 and women as old as 82. Routine genital electrocution of male Ukrainian prisoners.

This is just a fragment of the absolutely nightmarish stuff from the just-released UN report on sexual violence in Russia's invasion of Ukraine:

• Violations detailed in the report include rape, gang rape, genital mutilation, electric shocks, and genital beating
• Russian forces are responsible for the vast majority of sexual violence in Ukraine
• The majority of victims are Ukrainian men. In a common form of torture against Ukrainian POWs detailed in the report, Russian forces electrocuted men's genitals using tasers or a Soviet-era military field telephone known as a 'tapik.'
• Women and children, primarily in Ukrainian territory occupied by Russian forces, also fell victim to rapes and sexual assault. The youngest documented rape survivor was a four-year-old girl, and the oldest was an 82-year-old woman, with both cases perpetrated by Russian forces.
https://t.co/UHn1k8MLBX