The main issue with peanut butter in Kenya is that drying doesn't fix aflatoxin, it just stops it from getting worse.
A. flavus lives in Kenyan soil naturally. Drought-stressed pods get infected in the field, and that's when the toxin forms. Drying halts mold growth but can't destroy toxin already made, it survives roasting, grinding, even cooking.
With whole nuts you can pick out the bad ones. Peanut butter grinds the whole batch together, so a few heavily contaminated kernels get blended and averaged into every jar. Poor sorting = every spoonful carries risk.
Soil → fungus. Drought + pod damage + poor handling + weak sorting → the actual contamination. A batch can look and feel perfectly dry and still be loaded. Refined peanut oil is the outlier, aflatoxin stays behind in the solids during refining.
So, you are better off taking the peanut oil for your cooking and salads than eating peanuts due to the aflatoxins.
I was studying the latest GINA guidelines and made some bullet points about treatment of chronic asthma. I hope these will help you too
The BIGGEST change in GINA 2025:
No more SABA-only treatment.
Every patient with asthma must have an ICS-containing inhaler.
SABA alone = ↑ risk of exacerbations + mortality
COFFEE: Is it a friend or Foe?
Coffee is one of the most consumed beverages in the world. Yet myths about it refuse to die.
Let us separate facts from fiction. Bookmark this thread for future reference, and share for wider reach. Post your comments below.
1/n
Coffee is NOT just a wake-up drink.
Coffee contains hundreds of biologically active compounds, including polyphenols and antioxidants. In fact, for many people, coffee is one of the largest sources of antioxidants in the diet.
Have you ever noticed the line running across some tablets and wondered why it’s there?
Many people assume it is just part of the tablet’s design. In reality, it serves an important purpose.
That line is called a score line, and it is intentionally placed on certain tablets to help patients use their medicines correctly.
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CeraVe Acne Foaming Cream Cleanser & Acne Foaming Cream Wash have benzoyl peroxide that is unstable & degrades to benzene, a Group 1 human carcinogen, if exposed to prolonged or extreme heat.
Tropical Africans including Kenyans using these items are exposing themselves to cancer
The answer lies in understanding that naltrexone is not used for its peripheral opioid effects, but for its role in central appetite regulation pathways.
In the hypothalamus, POMC neurons regulate satiety. When these neurons are activated (for example by Bupropion), they release anorexigenic signals that reduce appetite and food intake.
However, this effect is naturally limited by an endogenous opioid-mediated feedback loop, which reduces POMC activity over time like a “brake” on satiety signaling.
Naltrexone blocks this opioid mediated feedback inhibition. As a result:
POMC activity remains sustained
Satiety signaling is prolonged
Reward driven eating and cravings decrease.
That is why naltrexone is used in combination with bupropion in obesity not as a standalone weight loss drug, but as a central amplifier of satiety signaling.
So the key concept is:
👉 Opioid antagonist, yes but in obesity, it is being used to block inhibitory feedback on satiety neurons, not to treat addiction pathways directly.
A consultant asked during ward round:
“If Naltrexone is an opioid receptor antagonist, how is it used in obesity treatment?”
This is a very important conceptual question👇
Once my mom and stepdad got scammed by a guy who knocked on the door and offered to fix the dents in their cars outside. He pretended to work on the cars, took the money, and then fled. My stepdad said the weird part was that the man did most of the correct steps to fix the dents, and obviously knew how it worked, but just decided not to finish it.
That's when I first saw a glimpse into the spirit of a scammer. It's not laziness or incompetence that drives them. Oftentimes the scammer works harder at scamming than they would at an honest job. What drives them is the incessant need to be better than everyone else to "get one over on" others. It's a truly perverse and awful way to live.
Eighteen years ago, as a medical student, I watched a physician glance at a patient's liver function tests.
I remember thinking they looked terrible.
The AST and ALT were elevated. I had just learned enough biochemistry to know the numbers were outside the reference range.
The doctor looked at the patient, asked a few questions, reviewed the history, and said:
"Nothing to worry about."
At the time, it felt almost reckless.
Today, after years in hospitals, I understand what I was actually witnessing.
Not knowledge.
Calibration.
A medical student sees an abnormal value.
A clinician sees a probability distribution.
The student sees AST 180 and ALT 220.
The clinician sees:
• The patient's age
• Medications
• Alcohol history
• Body habitus
• Symptoms (or lack of them)
• Previous reports
• Examination findings
• Hundreds of similar patients seen before
Most importantly, they have seen what happened next.
That last part is underrated.
Clinical judgment is built from feedback.
A physician who has followed thousands of patients develops an internal model that no textbook can fully teach.
The literature reflects this reality. Mildly elevated liver enzymes are common in clinical practice, and many abnormalities ultimately prove to be benign, transient, medication-related, metabolic, or otherwise non-catastrophic after appropriate evaluation rather than immediate alarm.
The laboratory value matters.
The patient matters more.
Medicine is not pattern recognition alone.
It is pattern recognition linked to outcomes.
That is why experience remains so valuable.
Not because experienced clinicians ignore data.
Because they have spent decades learning which data actually changes outcomes.
The novice sees the abnormality.
The expert sees the trajectory.
I once asked Pheroze Nowrojee why they kept challenging President Moi's authoritarian actions in Court in the 1990s when it was clear they would loose every time. He said:
"For the record! Nothing is more powerful in history than the record."
@ochieljd
https://t.co/k0mkJHze1D
President: " Sciences are so important, i cant stress this enough!"
Ugandan Government: " paying medical doc interns is unrealistic"
Politicians: " i'll fly to Germany for treatment then return to Uganda & build a church to thank God"