Our new genome annotation method relies almost entirely on transcriptome and alignment evidence, and as a result outperforms pretty much all other de novo pipelines. Paper just out, led by @AlekseyZimin5: https://t.co/RwRythVTU9
We have a 3-year postdoc position in our group at the HIFMB to study plasmids and plasmids systems of the marine environment to survey their utility in microbial responses to environmental change. Please see the official job ad here and spread the word:
https://t.co/ADOI2xAZnF
This by @SGRodriques laments the (anticipated) failure of models trained on large datasets to reproduce "real biology discoveries" like those found in Science and Nature. While he sees this as a problem, I COULD NOT DISAGREE MORE. That foundational models don't (and God help us won't) spit out Nature papers is a feature, not a bug!
Huge performance update in today’s dorado v0.9.1 release on Ampere 8.6/8.7 & Ada Lovelace 8.9 @nvidia GPUs with up to 2x increase in throughput with hac calling and 3x sup! 🚀
Plus a whole bunch of updates for dorado polish and the odd misc bug fix.
https://t.co/5S2KDFPnI1
Authcycler- a new tool for long-read bacterial genomes developed by @rrwick. Autocycler is a complete redesign focused on automation and speed. https://t.co/ryC07LNN8m #nanopore#bacteria
To close out 2024:
Vaccines save millions of lives every year.
Raw milk still isn’t safe.
Podcasts aren’t fact-checked.
Seed oils don’t cause cancer.
Everything is chemicals.
The dose makes the poison.
Using the word “toxic” without context is a red flag of pseudoscience.
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We are excited to introduce first-of-a-kind immunofluorescent probes to visualize RNA in cells! @NAR_Open
Synthetic anti-RNA antibody derivatives for RNA visualization in mammalian cells https://t.co/JDPtqrSFAi
2025 = 45^2
It's a perfect square. It will probably be the only perfect square year you ever get to live in.
The last time that occurred was in 1936. The next will be in 2116.
So, make 2025 a perfect year for you.
Some of my favorite books from 2024 (in no particular order): A Brief History of Intelligence by @maxsbennett
If you have an interest in evolution, the mind, and artificial intelligence, this one is for you. I would love to take a course based on this book
https://t.co/xiZ7cxk4o7
More proof that phage defense does not utilize what has been termed 'abortive infection' where the term means the nonsensical cell death. Best to not use this vague term.