JOAN BRUGGE

Cancer research investigator at Harvard Medical School; Co-director Ludwig Center at Harvard. Outside work love family, friends, tennis, scuba diving & cooking.

[JOAN BRUGGE @BruggeMe]

This interview from the Soledad O'Brien Show captures some of the issues for women's health and our lab's cancer research affected by the termination of federal grants at Harvard and elsewhere https://t.co/QDmVSPbTQt @harvardmed @AACR

[JOAN BRUGGE @BruggeMe]

@CarlFederl @harvardmed @AACR I lost my sister to brain cancer while in college and have dedicated my career to having an impact on cancer. It is difficult to have our research shut down for reasons unrelated to our work that I don’t have control over.

[JOAN BRUGGE @BruggeMe]

My two NIH cancer research grants were terminated today. One involving breast cancer prevention is an “outstanding investigator award” and had received a perfect score by reviewers. How does ending lifesaving cancer research make Americans healthier? @harvardmed @aacr

[JOAN BRUGGE @BruggeMe]

@CarlFederl @harvardmed @AACR This is about the advances in biomedical research that are compromised by the across-the-board termination of grants to people who have given their lives to biomedical research. Please try to separate this from your feelings about Harvard as an institution.

[JOAN BRUGGE @BruggeMe]

@H1jenwon @JonahDispatch @harvardmed @AACR We propose that they are the earliest precursors of breast cancer and are developing strategies to detect them and to kill them to prevent their progression to cancer. https://t.co/e16q2LRFv5

[JOAN BRUGGE @BruggeMe]

@H1jenwon @JonahDispatch @harvardmed @AACR Together with our collaborators, we have been using new technologies that allow us to sequence the genetic information in single breast cells and have four small populations of cells that carry only one or two of four the most common mutations associated with breast tumors. Con’t

[JOAN BRUGGE @BruggeMe]

@RogerRogergr @Carman_MC_Li @NatureGenetics Congratulations to Carman, Alyssa, Mike, Aiden, Mayura, Laura. Francesca. Nomeda, Gianmarco, Jason, Hana, Christina, Kushali, Shailja for the awesome work on this paper! Carman as lead deserves special recognition.

[Carman Li @Carman_MC_Li]

Our latest paper with Joan @BruggeMe is now out @NatureGenetics! We explore hidden mechanisms of BRCA1 hereditary breast cancer using new mouse models, revealing unexpected tumor-like chromatin changes in Brca1-heterozygous normal mammary cells.
https://t.co/SadDgqeRMC

[JOAN BRUGGE @BruggeMe]

@elonmuskADO Hi

[JOAN BRUGGE @BruggeMe]

@NWSSPC Mesoscale discussion?

[JOAN BRUGGE @BruggeMe]

We have an opening for a senior bioinformatics experts to work on two exciting projects relating to breast tumor evolution/prevention and ovarian cancer drug resistance. Highly collaborative group. Job ad: https://t.co/U1aF0Nc3Jj. #cancerresearch #Bioinformatics #cancertherapy

[JOAN BRUGGE @BruggeMe]

@ACKCurrent That is amazing.

[JOAN BRUGGE @BruggeMe]

@HarvardCellBio @HaigisLab awesome award Marcia. Congratulation!

[JOAN BRUGGE @BruggeMe]

@Jeff_Mold @ShoshaniOfer @arjunrajlab Could be because A549s have KEAP mutation causing hyper activation of NRF2

[JOAN BRUGGE @BruggeMe]

@nicholas_navin @MDAndersonNews MDACC chose a ‘giant’ to step into the shoes of the previous leaders of this excellent department. Congrats Nick!

[JOAN BRUGGE @BruggeMe]

Excited to share this Dev Cell report that defines subpopulations of breast cells and their links with age, parity, and risk of breast cancer. Great collaborative effort within the lab and with collaborators. https://t.co/X2luEfBJwE

[JOAN BRUGGE @BruggeMe]

@isaac_s_harris @g_asantewaa @fabiohecht @LabDeNicola @Muir_Lab @mvh_lab So happy for you Isaac. This is awesome!

[JOAN BRUGGE @BruggeMe]

Congratulations to Johan Kuiken and Sabin Dhakal and our collaborators on the publication of "Clonal populations of a human TNBC model display significant functional heterogeneity and divergent growth dynamics in distinct contexts"Oncogene https://t.co/8frMpSjVLd #cancerresearch