O'Casey

Аккаунт @coVce заблокирован после 14 лет.

В момент, когда я пишу эти строки, мне ещё нет сорока. ★ Смысловая нагрузка отсутствует.

Time is of the essence.

[O'Casey @c0Vce]

тез тез рамен по-домашнему

[O'Casey @c0Vce]

Как-то даже отвык штоли писать здесь.

[O'Casey @c0Vce]

@techdroider ok?

[O'Casey @c0Vce]

Динарка Сеулға барып келді.
BTS концертін көріпті.
З дорба косметика алып келіпті. Мен шаш жатқызатын сұрағам, тек Кореяда сатады екен осындай.

[O'Casey @c0Vce]

@ali_g_aka_kamaz на счет чего? не тема

[O'Casey @c0Vce]

@alim_zhan какой например

[O'Casey @c0Vce]

шәй жасап жатырмын

[O'Casey @c0Vce]

@MLarchanka фу иишный текст.

[O'Casey @c0Vce]

осы салатты көрсем бүкіл істеп жатқан жұмысымды тастап салат жеп кетем.

[O'Casey @c0Vce]

@UtdBloke_ fake

[Massimo @Rainmaker1973]

New research from King's College London shows that successfully treating apical periodontitis—a common chronic infection at the tooth root—through root canal therapy not only saves the tooth but also brings meaningful benefits to overall health, including reduced inflammation linked to heart disease and improved metabolic markers that could lower the risk of diabetes.

In this groundbreaking longitudinal study, researchers followed 65 patients for two years after they received root canal treatment for apical periodontitis. Using advanced nuclear magnetic resonance spectroscopy to examine blood serum metabolites, the team discovered clear improvements in those whose treatment successfully resolved the infection and promoted healing.

Patients showed meaningful declines in blood glucose and related compounds such as pyruvate, with these positive changes still evident at the two-year follow-up, suggesting better glycemic control and a potential reduction in the risk of developing type 2 diabetes. Lipid profiles also improved, with short-term reductions in cholesterol, choline, and circulating fatty acids that support better cardiovascular health.

In addition, key markers of systemic inflammation decreased over time, alongside drops in branched-chain amino acids observed as early as three months and increases in protective metabolites like tryptophan.

These findings indicate that eliminating the bacterial source within an infected root canal reduces low-grade systemic inflammation and bacteremia, processes that can otherwise contribute to cardiometabolic problems such as dyslipidemia, hyperglycemia, and heightened cardiovascular risk.

Lead author Dr. Sadia Niazi, Senior Clinical Lecturer in Endodontology at King's College London, highlighted the wider significance of the results. She explained that root canal treatment goes beyond improving oral health and may help protect against serious conditions like diabetes and heart disease, underscoring the deep connection between oral and systemic well-being.

The study emphasizes the importance of a more integrated, interdisciplinary approach to care. Closer collaboration between dentists and primary care providers could allow the use of specific blood markers to monitor recovery from dental infections and proactively address risks for chronic diseases. While larger studies are still needed to confirm and expand on these results, the work strengthens the growing body of evidence that resolving oral infections can deliver preventive health benefits far beyond the mouth.

[Zhang Y, Le Guennec A, Pussinen P, Proctor G, Niazi SA. (2026) "Successful endodontic treatment improves glucose and lipid metabolism: a longitudinal metabolomic study". J Transl Med. 2025;23:1123. doi:10.1186/s12967-025-07110-0]

[O'Casey @c0Vce]

@ali_g_aka_kamaz 😂 жәй қарапайым халыққо

[O'Casey @c0Vce]

қазақша пікірлер

[O'Casey @c0Vce]

@m1dwaaay кажется так и есть.

[O'Casey @c0Vce]

Ну чо как дела вообще твиторские?

Давно сюда не заглядовал нормально.

[д̷̆а̴̌͐̕р̵̹͈͖̘̭̣̙͖̭̯͎́͌͊͂̈́̈̃̓̚̚͝ͅӓ̷̛́̋͑͊̆̄̅̃͋ @m1dwaaay]

@c0Vce Твиттер умер, бро.

[O'Casey @c0Vce]

Қыз қандай керім жақсы,бірақ Смиттің ұлы клоун 🤡

[Redd @ReddCinema]

generational fumble…

[O'Casey @c0Vce]

@ESPNUK ok

[O'Casey @c0Vce]

💔