Automated Synthetic Lethality Papers

Daily RSS feed for papers on Synthetic Lethality in Cancer. cancer AND (synthetic lethal OR synthetic lethality). Largely automated, don't expect responses

[Automated Synthetic Lethality Papers @cancerSL]

due to @dlvrit stopping their free plan (understandable) it seems this account will stop posting in the coming weeks. back to pubmed searches!

[Automated Synthetic Lethality Papers @cancerSL]

VHL synthetic lethality screens uncover CBF-beta as a negative regulator of STING [NEW RESULTS] https://t.co/Rj5HLMw2vj

[Automated Synthetic Lethality Papers @cancerSL]

Discovery of Novel, Potent and Orally Bioavailable SMARCA2 PROTACs with Synergistic Anti-tumor Activity in Combination with KRAS G12C Inhibitors. [NEW RESULTS] https://t.co/PHK8oLgWmM

[Automated Synthetic Lethality Papers @cancerSL]

Inhibition of heme biosynthesis triggers cuproptosis in acute myeloid leukaemia. [NEW RESULTS] https://t.co/JwIsNKWwQe

[Automated Synthetic Lethality Papers @cancerSL]

Genome-wide CRISPR screen identifies KEAP1 perturbation as a vulnerability of ARID1A-deficient cells [NEW RESULTS] https://t.co/Q6B9AIzAvO

[Automated Synthetic Lethality Papers @cancerSL]

SLInterpreter: An Exploratory and Iterative Human-AI Collaborative System for GNN-based Synthetic Lethal Prediction https://t.co/Ygyqg3oVrJ

[Automated Synthetic Lethality Papers @cancerSL]

Mapping Genetic Interactions of All Paralogs in the Human Genome [NEW RESULTS] https://t.co/eXEF7OJFbZ

[Automated Synthetic Lethality Papers @cancerSL]

Integrated multiomic profiling reveals SWI/SNF subunit-specific pathway alterations and targetable vulnerabilities [NEW RESULTS] https://t.co/a4FlLbxaaD

[Automated Synthetic Lethality Papers @cancerSL]

Cx43 Enhances Response to BRAF/MEK Inhibitors by Reducing DNA Repair Capacity [NEW RESULTS] https://t.co/rtPCdKvZNt

[Automated Synthetic Lethality Papers @cancerSL]

RBM10 loss induces aberrant splicing of cytoskeletal and extracellular matrix mRNAs and promotes metastatic fitness. [NEW RESULTS] https://t.co/zNRxTW5HOe

[Automated Synthetic Lethality Papers @cancerSL]

Integrating Multi-Modal Cancer Data Using Deep Latent Variable Path Modelling [NEW RESULTS] https://t.co/0bBUXKw406

[Automated Synthetic Lethality Papers @cancerSL]

Loss of FBXO31-mediated {gamma}H2AX foci formation impairs initiation of NHEJ and HR repair pathways, and sensitizes breast cancer to therapy [NEW RESULTS] https://t.co/rVDhwloSrV

[Automated Synthetic Lethality Papers @cancerSL]

Finding novel vulnerabilities of hypomorphic BRCA1 alleles [NEW RESULTS] https://t.co/hL8QdQgF15

[Automated Synthetic Lethality Papers @cancerSL]

ZNF251 haploinsufficiency confers PARP inhibitors resistance in BRCA1-mutated cancer cells through activation of homologous recombination [NEW RESULTS] https://t.co/sL7CMNGuyu

[Automated Synthetic Lethality Papers @cancerSL]

CRISPR Double Knockout Library Reveals Synthetic Lethal Gene Pairs in Triple-Negative Breast Cancer [NEW RESULTS] https://t.co/1gPwwXxghP

[Automated Synthetic Lethality Papers @cancerSL]

Identifying Novel Therapeutic Targets for Overcoming TNBC Chemo Resistance Through Comprehensive CRISPR-Cas9 Genome Screening [NEW RESULTS] https://t.co/ZaF6qwWdrl

[Automated Synthetic Lethality Papers @cancerSL]

Epigenetic targeting of PGBD5-dependent DNA damage in SMARCB1-deficient sarcomas [NEW RESULTS] https://t.co/U98L8xUmvZ

[Automated Synthetic Lethality Papers @cancerSL]

Chemoresistance to additive PARP/PI3K dual inhibition in triple-negative breast cancer cell lines is associated with adaptive stem cell-like prevalence [NEW RESULTS] https://t.co/dniMTrBqrs

[Automated Synthetic Lethality Papers @cancerSL]

Identification of MYC synthetic lethal genes and networks [NEW RESULTS] https://t.co/6kTI94vNoT

[Automated Synthetic Lethality Papers @cancerSL]

Rampant transcription replication conflict creates therapeutic vulnerability in extrachromosomal DNA containing cancers [NEW RESULTS] https://t.co/v57fPd0KHb