α-Klotho as a central integrative signalling hub in cognitive function and neuroprotection in neurodegenerative diseases
"Overall, α-Klotho stands as a novel biomarker and a promising intervention strategy for mitigating neurodegeneration and promoting healthy brain ageing."
https://t.co/EhELKHWE74
New Research: Emerging non-D2 receptor-based therapies for schizophrenia: a focus on muscarinic and glutamatergic pathways https://t.co/idHtg9ATM6 #FrontiersIn#Psychiatry
New Research: Cross-cultural associations between behavioural, emotional, and cognitive differences in autistic children and parental wellbeing: evidence from five countries https://t.co/EBytHxy84K #FrontiersIn#Psychiatry
Here's how weight loss meds for antipsychotics ranked in new meta-analysis:
https://t.co/H0TUrJFwbo
1 Semaglutide (11 kg)
2 Liraglutide (5.4 kg)
3 Topiramate (4 kg)
4 Metformin (4 kg)
5 Exenatide (3 kg)
For non-med options, diet, exercise, probiotics, and melatonin.
📄 New publication in @FrontNeurosci !
Our latest review examines how cellular senescence across the brain–body axis may contribute to brain aging and neurodegeneration, highlighting new opportunities for biomarkers and future therapeutic strategies.
👉 https://t.co/39vZsve8Mi
Una vacuna española abre una nueva vía para frenar el #párkinson: "En el peor de los casos, que vaya más lento, y en el mejor de los casos, que no progrese" https://t.co/i5T8oq1m7D vía @COPE
Borderline Personality Disorder (BPD) isn’t just “emotion dysregulation.”
It can be usefully conceptualised as a predictive-processing problem where salience, reward prediction errors (RPEs), and the endogenous opioid system (EOS) bias social learning.
Here’s how clinicians can help patients update predictions and reduce volatility. 🧵👇
Serum 25-Hydroxyvitamin D Concentration as a Biomarker and Immunomodulator in Patients with Acute Ischemic Stroke: A Retrospective Single-Center Study https://t.co/M4lUmcADyr
A recent study led by NIH-supported researchers found that participants in a structured mindfulness-based intervention program showed modest but clinically meaningful improvements in cardiovascular health. The study was funded by NIH’s National Center for Complementary and Integrative Health.
Read more: https://t.co/F4Uh42KtDD
Glucosamine, a popular joint supplement combining glucose and glutamine, which can cross the blood-brain barrier, was linked to faster Alzheimer’s progression. Interesting research that further highlights the connection between sugar and Alzheimer’s. https://t.co/DxG7BDm5WJ
New Research: Distinct patterns of default mode network functional connectivity between adolescents with bipolar disorder and major depressive disorder https://t.co/FoihXdzPOF #FrontiersIn#Psychiatry
New expert consensus on anhedonic depression points to:
▪ Bupropion, dextromethorphan, ketamines, pramipexole
▪ Vortioxetine, agomelatine, aripiprazole, brexpiprazole, cariprazine
▪ TMS, CBT, exercise
And away from SSRI/SNRIs
Learn more in summary:
https://t.co/SLpsDfVnVM
Dormir es necesario para el cerebro y más cuando uno viene muy cansado del trabajo. La razón es que hay procesos complejos bioquímicos que ayudan a regenerar neuronas y evitar proteínas tóxicas , por lo que se puede considerar una medida preventiva para las demencias