Caspase Lab

The Baena-Lopez lab is interested in uncovering the non-apoptotic role of caspases using Drosophila.

[Derek Xu @derekcxu]

Oops, didn’t realize @CellReports had a twitter account!

Also adding here some pretty #microscopy images related to the work in the paper linked above: Drosophila macrophages (yellow and red) residing on imaginal wing disc tumors (purple and blue/green)

[Caspase Lab @CaspaseLab]

… This paper is a result of a collaboration with Dr. Ken Yamada in the @NIH/@NIDCR with @derekcxu as a shared @NIHOxCam student, with support from @CRUKresearch, and the wonderful friends and colleagues at the @Dunn_School.

3/3

[Caspase Lab @CaspaseLab]

Happy to announce that we’ve published a new research article about the non-apoptotic tumor suppressing role of caspases in @CellReports! Congratulations to @derekcxu and Li Wang! Please read the paper here: https://t.co/YBAHo2IhET #CancerResearch #caspases #drosophila

1/3

[Caspase Lab @CaspaseLab]

… In this paper we detail how widespread activity of the Drosophila caspase Dronc suppresses tumor growth by inhibiting key signaling pathways, altering the tumor microenvironment, and limiting the recruitment of tumor-promoting immune cells—independently of apoptosis.

2/3

[Caspase Lab @CaspaseLab]

Congratulations DR. Claire Hill!! Well done and a great achievement!

[Claire Hill @ClaireHill_]

PhD viva completed! Thanks to all the wonderful people who helped me along the way during the past 4.5 years @CaspaseLab @DaveCarter1234 @LizzieDellar @ale_gal79 @derekcxu @Jana_AloLor @LewisArthurton @WendlerFranz to name just a few ❤️👩‍🔬 There are too many to thank in person!

[Dunn School GSA @Dunn_GSA]

💡Feature Friday💡

For this week's #FeatureFriday we have Claire (@ClaireHill_),
a final year Interdisciplinary Bioscience PhD student who works in the Baena Lopez lab at the @Dunn_School, in collaboration with the Carter lab at Oxford Brookes! (1/n)

[Lizzie Dellar @LizzieDellar]

Can't quite believe today is finally here, but thesis is finally in! Thanks to @CaspaseLab and @DaveCarter1234 for getting me here, and @ClaireHill_ for working with me all the way!

[Caspase Lab @CaspaseLab]

@LizzieDellar @DaveCarter1234 @ClaireHill_ Congratulations Lizzie!! Well done :)

[Claire Hill @ClaireHill_]

Big congratulations to Dr @derekcxu on passing his viva today!! The most recent grad from @CaspaseLab!
We can't celebrate like we would like to....just yet. 🥳🎓😄

[Claire Hill @ClaireHill_]

Congrats to the best PhD project buddy there is @LizzieDellar who just won the Best Flash Presentation Award at the @UKEVSoc ECR event! Well done and well deserved!

[Caspase Lab @CaspaseLab]

Congrats to Franz, @ClaireHill_ and @ale_gal79 for their work on this preprint resulting from a collaboration with Seung Kim Lab! With the hard work of some undergraduate students on a Stanford-Oxford course we've created a new tool for Drosophila to generate and induce genes :)

[Claire Hill @ClaireHill_]

Happy to be part of this pre-print from @CaspaseLab
and Seung Kim Lab describing an exciting new #Drosophila tool.
It all started from a Stanford-Oxford summer course in 2019. I had the chance to be a demonstrator for a group of wonderful undergraduate students!

[Caspase Lab @CaspaseLab]

A preprint of our PhD student @derekcxu's first first-author paper is out on @biorxivpreprint! Read about widespread non-apoptotic tumor-suppressing caspase activity in Drosophila! https://t.co/R4doAeOoEW

[Caspase Lab @CaspaseLab]

You can do it @ClaireHill_!

[Claire Hill @ClaireHill_]

Currently carrying the weight of my PhD on my shoulders. Not just symbolically but literally. 1 laptop. 4 lab notebooks. 3 hard drives. Get me home and get the thesis started. Little earlier than planned but I'm rolling with it.

[Barack Obama @BarackObama]

Watch this. It shows why we should all do the right thing and stay home to the fullest extent possible. All of us can help slow the spread of the virus, protecting the elderly, the vulnerable, and each other. https://t.co/FgffQrMVB7

[Caspase Lab @CaspaseLab]

Congrats to @ClaireHill_ for winning the talent show at this year's @Dunn_School's Christmas Party!

[Caspase Lab @CaspaseLab]

Congrats to our first PhD student @LewisArthurton successfully defending his thesis and passing his viva! When he joined he was our lab's spring chicken but now he is Dr. Springy :)

[Caspase Lab @CaspaseLab]

Thanks for coming and giving a great talk Patrick! Hope you enjoyed your visit as we did.

[Patrick Blader @PatrickBlader]

Thanks to Alberto Baena Lopez @Dunn_School for inviting me for a talk today ... had a great time and fantastic discussions. Fun to be back in Oxford again.

[Caspase Lab @CaspaseLab]

This week we wrapped up a great first ever meeting on The Non-apoptotic Roles of Apoptotic Proteins, where we presented some work from our lab, and our favorite postdoc Dr. Alessia Galasso @ale_gal79 won a another poster prize for her work! 2/2 this year :)

[Caspase Lab @CaspaseLab]

Congratulations our Dr. Galasso @ale_gal79 winning first prize for her poster at the Oxford Stem Cell Institute Annual Symposium this year! Wonderful work!

[Angela Russell @AJR_group]

Many congratulations to OSCI 2019 poster prize winners Alessia Galasso (1st), Laurence Silpa (2nd), Nadia Nasreddin (3rd). Sponsored by Eurofins Discovery.

[Irene Miguel-Aliaga @FlyGutLab]

Testes are hungry; they want citrate. They talk to the gut and make it male. The male gut feeds citrate to the testes. Testes are happy. They make sperm. Lab’s latest and the filthiest of summer reads: https://t.co/MKzogJDkGI