Paul Castillo MD

Assistant Professor, Pediatric Hematology/Oncology and Stem Cell Transplantation @UFHealth. Immunotherapy Researcher @UFBTIP. Views are my own.

[Paul Castillo MD @castillopa5]

Great teamwork at the Pediatric Cancer Immunotherapy Initiative ⁦@UFHealthCancer⁩ ⁦@UFMBI⁩ ⁦@Rosen_NeuroOnc⁩ shows that RNA-lipid particles mediate immune checkpoint inhibition and epitope spreading by early response type-I interferons. https://t.co/dIzQadDDyR

[Paul Castillo MD @castillopa5]

@nataliesilvermd @McGrailResearch @caseccc @CLEImmunoUpdate @ClevelandClinic Major Congrats Natalie!

[Paul Castillo MD @castillopa5]

@ProfGregSawyer @MoffittNews @HLeeMoffitt1 Major congrats Greg!

[Journal of Clinical Investigation @jclinicalinvest]

Deconstructing the lair in glioblastoma

Jianping Huang & team @uflorida find block of the immune checkpoint LAIR1 with an antibody or 3-in-1 CAR T cells enhances antitumor response: https://t.co/tzIC0aSf2h

Check out the effect of a LAIR1 blocking antibody on CAR T cells, M2-like macrophages, and human glioma tumor spheres.

[Paul Castillo MD @castillopa5]

@adam_grippin @ACKoongMDPhD @MDAndersonNews @ASCO Major congrats Adam!

[UF Health Cancer Institute @UFHealthCancer]

UF Health Cancer Center researchers have found that a genetic alteration may predict the outlook for patients with Ewing sarcoma. Published in @MolOncology, the findings could ultimately help clinicians personalize clinical-decision-making.

Read more: https://t.co/G2hV8INQ8v

[Elizabeth Ogando-Rivas @ogandorivas]

If you are looking for US clinical experience in #neurosurgery, this is a great opportunity! Apply for Neurosurgery Pre-Residency #Fellowship at University of Missouri #Match2025

[UF College of Medicine Office of Research @UFMedResearch]

Attention @UFMedicine faculty! The 2025-26 R01 Boot Camp mentee application opens April 1st, 2025! The R01 Boot Camp is a 9-month team-science and mentorship-focused program designed to help faculty member receive R01 or equivalent grants. Learn more at https://t.co/JUWX019FfZ.

[UF Health Cancer Institute @UFHealthCancer]

.@UFHealth pediatric oncologist @JohnLigon has launched a new clinical trial to test a novel @UF-developed mRNA lipid nanoparticle (RNA-LP) in children with recurrent high-grade glioma and recurrent osteosarcoma: https://t.co/a7WaI6K8A1

[Jatinder Lamba Lab @LambaJK_Lab]

Happy to share our article in Blood Advances. Great work by grad student Dr. Nam Nguyen, lab alumni Dr. Raffie and current postdoc Dr. Phani Parcha

Genome-wide CRISPR/Cas9 screen identifies AraC-daunorubicin-etoposide ... https://t.co/POEjOuZQx6

[From the Labs at Baylor College of Medicine @BCMFromtheLabs]

Drs. Brenner, Rooney named National Academy of Inventors Fellows. @AcadofInventors @bcmhouston @BCMDeptMedicine @bcmgenetics @BCMCancerCenter @CAGTHouston https://t.co/Krp1MolKbp

[Paul Castillo MD @castillopa5]

Major congrats @CapitiniMD!

[UW Health | Carbone Cancer Center @UWCarbone]

Dr. Christian Capitini has been appointed to serve as the acting director of @UWCarbone. He currently serves as the chief of @WiscPediatrics Division of Hematology, Oncology and Bone Marrow Transplant. He succeeds Dr. Howard Bailey who has served as director since 2015.

[Heczey Lab @HeczeyLab]

IL15 increases the expansion of CAR T cells and induces antitumor responses in patients with GPC3+ solid tumors (i.e. liver cancer).
https://t.co/ybNobLrQvy

[Paul Castillo MD @castillopa5]

Amazing work! Major congrats Andras, David and team! @HeczeyAndras @davidsteffin

[Waggoner Lab @LabWaggoner]

IL-15-armoured GPC3 CAR T cells for patients with solid cancers
https://t.co/V35WpzehmG
@Nature @davidsteffin @AHeczey

[Paul Castillo MD @castillopa5]

@may_khanna @Bruskolab @UF @UFMedicine @UFMedResearch Major Congrats Dr Brusko! Very well deserved!

[Paul Castillo MD @castillopa5]

Very nice work Adam and team!

[UT MD Anderson @UTMDAnderson]

How might COVID mRNA vaccines improve clinical responses to immune checkpoint inhibition? Our fellow Dr. @Adam_Grippin shared findings (Abstract 1037) at #SITC24.
Learn more: https://t.co/xKI1EmhJE9 @SITCancer #EndCancer

[Paul Castillo MD @castillopa5]

@UFHealthCancer @UFHealth @Lakeshia_APRN @UFNursing Strong work Lakeshia!

[Paul Castillo MD @castillopa5]

@jdlicht @aaas @LCottler @UFMedicine @UFHealth @UFPHHP @UF Major congrats Dr Licht! Very well deserved!

[Paul Castillo MD @castillopa5]

@TCHHemOncFellow @texas Congrats my friend! All the best!

[Fan Zhang (張帆) @FanZhangPhD]

📢 We're also looking for passionate grad student & undergrads for #Fall2025 in #PharmaceuticalScience, #ChemicalEngineering, and #BiomedicalEngineering. Apply to @UF_Pharmacy & @UFChemEng! #GoGators #ResearchOpportunity