Christopher Benway

Sr. Bioinformatics Scientist @ExosomeDx @biotechne

[Christopher Benway @cbenway]

📊 EV-RNA gene expression outperformed the other analytes, achieving 54.8% (!) sensitivity (95% CI: 26.4–75.6%) for detecting advanced adenomas, a significant precursor to CRC. This work highlights the unique diagnostic power of EVs for early, non-invasive cancer detection!

[Christopher Benway @cbenway]

Behold, the power of exosomes! 🧬💧

Check out our new preprint, “Extracellular Vesicle Gene Expression Enables Sensitive Detection of Colorectal Neoplasia” on bioRxiv: https://t.co/OHRcfUqvyH

[bioRxiv Genomics @biorxiv_genomic]

Extracellular Vesicle Gene Expression Enables Sensitive Detection of Colorectal Neoplasia https://t.co/NPmLUMLAD9 #biorxiv_genomic

[Christopher Benway @cbenway]

We applied a rigorous machine-learning cross-validation framework to evaluate detection of colorectal cancer (CRC) and advanced adenomas (AA) using multiple blood plasma analytes (EV-RNA, EV-miRNA, EV-proteomics, and methyl-cfDNA).

[Michelle McNulty @m_t_mcnulty]

Check out 2 new preprints from the Sampson & Lee labs! Thanks to all the awesome folks in our labs and collaborators around the country! #kidneyomics 🫘🧬

[ATS Red Journal @AJRCMB]

Chromatin Landscapes of Human Lung Cells Predict Potentially Functional Chronic Obstructive Pulmonary Disease Genome-Wide Association Study Variants

🔗 https://t.co/ZQZu9oDAog

[ATS Red Journal @AJRCMB]

Functional Gene Variants in Chronic Obstructive Pulmonary Disease: The Search Continues

🔓 Open Access
🔗 https://t.co/xksFPKZcOk

[ATS Red Journal @AJRCMB]

Connecting COPD GWAS genes: FAM13A controls TGFβ2 secretion by modulating AP-3 transport

✅ Just Accepted
🔗 https://t.co/OUjxViElCC

[AJP-Lung Cellular and Molecular Physiology @AJPLung]

New #ResearchArticle in @AJPLung: A Systematic Analysis of Protein-altering Exonic Variants in #ChronicObstructivePulmonaryDisease. Read more here: https://t.co/QffCPiftsN
#COPD #Functional #Genomics @mikecho95
Pic (l-r): Brian D Hobbs @BrianDHobbs & Matthew Moll @MattMollpulmccm

[ATS Red Journal @AJRCMB]

Functional Gene Variants in COPD: The Search Continues

✅ Just Accepted
🔗 https://t.co/bCsIMPd2uj

[ATS EOPH @ATS_EOPH]

Chromatin Landscapes of Human Lung Cells Predict Potentially Functional COPD GWAS Variants. Benway et al. Am J Respir Cell Mol Biol. 2021 Mar 31.
https://t.co/6GJ9d1iVVf

[Christopher Benway @cbenway]

GWAS Functional Variant rs2076295 Regulates Desmoplakin (DSP) Expression in Airway Epithelial Cells | American Journal of Respiratory and Critical Care Medicine | Articles in Press https://t.co/u28jZHM9wd

[Matthew Moll, MD, MPH @MattMollpulmccm]

So if anyone is interested in non covid stuff, our paper using machine learning to predict all cause mortality in #COPD came out: https://t.co/ZpqWSuYvz2

The web app is here: https://t.co/UCw2zlyUAA

Thanks @accpchest

[ATS BSHSR @ATS_BSHSR]

Genetic Advances in #COPD: Insights from #COPDGene #Pulmonary https://t.co/rLFyWLyZIx

[Craig Hersh MD @craig_hersh]

Have we found the genes for COPD? @MegRaglandMD reviews results from the #COPDGene study @nih_nhlbi
Genetic Advances in COPD: Insights from COPDGene | American Journal of Respiratory and Critical Care Medicine | Articles in Press https://t.co/tOoI3Oqo4l

[Michael Cho @mikecho95]

Our paper Genetic Landscape of COPD now out in @NatureGenet - fantastic job by @PhuwanatS @BrianDHobbs #ICGC and wonderful collaborators: https://t.co/78urxbg5Fq

[Phuwanat @PhuwanatS]

Our recent work on GWAS of COPD led by @mikecho95 and @BrianDHobbs has been published in @NatureGenet https://t.co/O480C0tLVq

[Nature Genetics @NatureGenet]

2 new papers on COPD and lung function: https://t.co/2RXUG3wvxn & https://t.co/g36F6EtPtH

[American Journal of Transplantation @amjtransplant]

AJT's April issue is out! Still Targeting Calcineurin Toxicity -- read the #CoverArticle from Benway and Iacomini (@TuftsMedSchool) at https://t.co/wiiW7pbkM4. #transplantation

[microRNApapers @microRNA_papers]

Defining a microRNA-mRNA interaction map for calcineurin inhibitor induced nephrotoxicity. https://t.co/EPNqlOGBaB