Glad to share the artwork of our DNA supercoiling work now in the cover of @MolecularCell ! This cover was inspired in traditional Peruvian embroidery @peru 🇵🇪 to represent artistically our findings on apical localization of RNA polymerases on DNA plectonemes.
#MarcaPerú#Peru
How do DNA duplexes recognize and pair with each other?
Thomas Catley, @VVBerrelleza, @alicepyne and myself present the first direct visualization of DNA-DNA pairing mediated by divalent cations, confirming the decade-old DNA zipper model!
https://t.co/2Fs5ZZXGyw
Excited to share our new preprint!🧬❄️ by brilliant Max Dreimann & Co! Using cryo-ET&EM, we reveal archaeal chromatin in a near-native state: variable-beads-on-a-string fibers shaped by growth phase and histone composition https://t.co/WEg93XeTpe
We thank @NatureSMB for the highlight on our Transcription/DNA supercoiling work.
Transcription from supercoiled DNA | Nature Structural & Molecular Biology
https://t.co/mpm7f7NGlt
Glad to share the artwork of our DNA supercoiling work now in the cover of @MolecularCell ! This cover was inspired in traditional Peruvian embroidery @peru 🇵🇪 to represent artistically our findings on apical localization of RNA polymerases on DNA plectonemes.
#MarcaPerú#Peru
You can find more on our work at
Apical localization of RNA polymerases modulates transcription dynamics and supercoiling domains revealed by cryo-ET: Molecular Cell https://t.co/Vc4vGoeJ0y
Finally out in @Cellcellpress!
Proteins with long intrinsically disordered regions (IDRs) are prone to misfolding during protein synthesis.
This is prevented by mRNA 3′UTRs that act as mRNA-based IDR chaperones.
https://t.co/Pa4bWYhOMe
Out now in Science! Our new study challenges long-standing assumptions about transcription factor specificity in eukaryotes. Novel single-molecule measurements of TF behavior in living cells reveal an independence of locus-specific binding from DNA sequence recognition.🧵
https://t.co/w5mYmh4I1G
Everything you wanted to know about the protein chemistry behind how amino-acid changes affect the cellular abundance of proteins
Effects of residue substitutions on the cellular abundance of proteins
https://t.co/FwoD1kiF30
Happy to share our new work published in @acsnano "Quantifying Photochemical Propulsion in Light-Powered Janus Micromotors". A collaboration among @BustamanteLab, Alivisatos lab and the Molecular Foundry
https://t.co/zByMTgdHWg
Excited to share our work uncovering SNOR, a ribosome-associated factor that promotes translation restart after dormancy published in Nature!! This was, as usual, a wonderful collaborative effort between our group @UVA and @simonemattei@EMBLHeidelberg
https://t.co/YKDCLFowvC
Excited to share our new work published in @MolecularCell: “Apical localization of RNA polymerases modulates transcription dynamics and supercoiling domains revealed by cryo-ET”. We directly visualized transcription-induced DNA supercoiling domains in 3D! https://t.co/3TEtfoQfRO
Happy to share that our latest work at UC Berkeley is now published in @acsnano. A collaboration among @BustamanteLab, Alivisatos lab and the Molecular Foundry @molecularfndry.
Quantifying Photochemical Propulsion in Light-Powered Janus Micromotors
https://t.co/Mc8eIL0wqJ