Éric Bergeron

Studying viruses causing hemorrhagic fever and how we can stop them. Personal opinions.

[Éric Bergeron @cchfvirus]

@fablabpitt @BenteLab @BadBugDoc @florian_krammer @CesarMFontela And then it got white for real.

[Éric Bergeron @cchfvirus]

@fablabpitt @BenteLab @BadBugDoc @florian_krammer @CesarMFontela I just started coloring my hair gray to look cooler 😂

[Éric Bergeron @cchfvirus]

@BenteLab @DrSusanNasif Found this on researchgate:

Abnormal life cycle of hyalomma dromedarii (acari: Ixodidae) on single-
humped camels in semnan, north-east of Iran

[Éric Bergeron @cchfvirus]

@BenteLab @DrSusanNasif Good question but reading a little bit on this it sounds like this tick can have a 1- 2- or 3 hosts life cycle. Maybe they can survive just by feeding on camels?

[Éric Bergeron @cchfvirus]

Amazing work, congratulations to Prometheus consortium!

[Kartik Chandran @ChandranLab]

Excited to share latest work in @CellCellPress from our Prometheus consortium (pic). Our charge is to discover and develop human antibody-based therapeutics against emerging viral threats. See thread below.
Author version of paper: https://t.co/yq9q9Uv0ie

[Éric Bergeron @cchfvirus]

We currently recruiting a postdoc fellow to work on the development of a vaccine for Crimean-Congo hemorrhagic virus (CCHFV). This is work is collaboration with UGA and will involve work in BSL-4. Interested candidate can apply here👇

https://t.co/nh55WLzdXi

[Éric Bergeron @cchfvirus]

@MattFrieman ACE2 can be shed from the cell surface by the TNF-alpha converting enzyme (TACE). This might contribute to blocking SARS-2 entry. Many surface proteins can be shed. This is particularly common when using over expression systems.

[Éric Bergeron @cchfvirus]

@VirusWhisperer @florian_krammer What about people working at grocery stores sounds like a priority to me?

[Éric Bergeron @cchfvirus]

Current COVID and SARS-CoV-1 data suggest that vaccine approaches aimed at generating neutralizing antibodies might not be the best approach for COVID. Nice summary @VirusesImmunity

[Prof. Akiko Iwasaki @VirusesImmunity]

This is a cautionary tale of how anti-Spike antibody may make COVID disease worse. In this study, the authors show that anti-Spike IgG made SARS-CoV disease worse by switching macrophage from wound-healing to proinflammatory phenotype. A thread (1/n)

https://t.co/T8ipHt5tRH

[Prof. Dr. Benhur Lee, MD 🦠🧬🔬 @VirusWhisperer]

#COVID19 #SOS To my professional colleagues & anyone out there who can help; we are seriously low on BSL-3 PPE. COVID-19 research will be compromised if we run out of them. #FaceShields #EyeProtection (googles), #Disposable booties, anything for additional barrier of prevention.

[Emily Bruce, PhD @poisondartfrog7]

1/n Our work describing the adaptation of the CDC RT-qPCR assay for use with alternative Qiagen RNA extraction kits, as well as skipping the RNA extraction step entirely is live on bioRxiv. Pls retweet. #coronavirus #COVID19 #StayAtHome https://t.co/cGK8O5lUts

[Éric Bergeron @cchfvirus]

@RobertWCross1 Totally agree with his comment. Seeking perfection in these situations is detrimental overall and not acheivable to start with.

[Éric Bergeron @cchfvirus]

@florian_krammer @MattFrieman Looking at the methods, they use a goat-anti mouse HRP conjugate. Does not sound optimal since those are Rhesus ... Any good study showing ELISA data in humans?

[Éric Bergeron @cchfvirus]

@RobertWCross1 @McLellan_Lab @ZABornholdt @LarryZeitlin @ChandranLab Great to see part of the puzzle uncovered. Congrats!

[Éric Bergeron @cchfvirus]

@stevewelch23 @BenteLab @fablabpitt I know, same thought when I saw that pic 😂

[Jessica Spengler @VirusVetty]

Now accepting original high-quality research and reviews for #HemorrhagicFeverViruses Special Issue! #HFV #VHF #Lassa #CCHFV #Ebola @Pathogens_MDPI

https://t.co/2sNST5FGej

[Timothy Sheahan @timothysheahan]

Wow! This one makes at least 3 new human coronavirus since 2002. Let’s get to work. #sars #mers #WuHanPneumonia #emergingviruses #zoonotic

[MicrobeTV @profvrr]

The latest episode of the #science #podcast This Week in Virology #TWiV is the biggest ever: 8 guests discuss development of antibody-based therapeutics against tick-borne Crimean-Congo hemorrhagic fever virus and rodent-borne hantaviruses https://t.co/uSMX1llw5N

[Erica OllmannSaphire @EOSaphire]

We're hiring a research tech to do cloning and protein design for #Ebola and other #EmergingViruses @ljiresearch. Organized? Interested in #virology and #immunology? Want to work at a top-five research institute in La Jolla, Calif.? Email me thru https://t.co/8f7SzSCSHl Please RT

[Éric Bergeron @cchfvirus]

@BenteLab @brennanlab @ticks7 These antigen capture assays were quite ok back in the days. But yes you might have false negatives is there is not enough glycoproteins but there are ways to amplify signal that might help. Maybe just a strand specific rt-pcr could be enough?