Eric H Chang

Neuroscientist | Assoc Professor, Feinstein Institutes @NorthwellHealth @ZuckerSOM | Neuro-immune interactions, bioelectronic medicine, IBD, cancer | Views mine

[SetPoint Medical @SetPointMed]

New 24-month RESET-RA data at #ACR26 show sustained clinical responses and favorable long-term safety with the SetPoint System for rheumatoid arthritis.

Learn More: https://t.co/5vCuxWelNY

Safety Info: https://t.co/qhIkZcvrkO

[Eric H Chang @changsbrain]

@sidelinesync Travel

[suhauna hussain @suhaunah]

California voters appear to have approved Proposition 38, which was authored by billionaire Gary K. Michelson and will fund his immunology research institute to the tune of $4.2 billion. But the institute had only 3 employees as of September. @mzinshteyn https://t.co/qZpBwqtpc5

[Kevin Zhang @kevinyzhang]

Mindblowing, 93% reduction of epilepsy episodes for patients who aren’t responding to current drugs.

Virus delivers an off switch (programmable “hardware”) to neurons that are overly excitatory, then patients take a low dose drug (“software”) to activate the off switch. First time in humans, what a time to be alive.

[Eric H Chang @changsbrain]

This is amazing. The more I learn about Dr. El-Sayed, the more impressed I become!

[John J. Foxe @JohnnyFoxe]

Newly elected Senator Abdul El-Sayed has an H-Index of 37. This makes me inordinately happy. Expertise matter. Science matters. Facts matter. Rationality is a magic power -- @AbdulElSayed
#ScienceMatters #FactsMatter #BLUEWAVE

[John J. Foxe @JohnnyFoxe]

Newly elected Senator Abdul El-Sayed has an H-Index of 37. This makes me inordinately happy. Expertise matter. Science matters. Facts matter. Rationality is a magic power -- @AbdulElSayed
#ScienceMatters #FactsMatter #BLUEWAVE

[Eric Topol @EricTopol]

We shouldn't underestimate the power of vagus nerve modulation. Today the potential for Parkinson's disease. Noninvasively.
Work in the experimental model @natBME
https://t.co/HHnEvPWXzl

[Dr. Catharine Young @DrCatharineY]

Here is a comprehensive list of scientists and medical doctors confirmed so far to have been elected or reelected last night, across both parties and at the federal and state levels:

U.S. SENATE

Dr. Annie Andrews | South Carolina
@AnnieAndrewsMD | Pediatrician

Dr. Abdul El-Sayed | Michigan
@AbdulElSayed | Physician and epidemiologist

GOVERNORS

Dr. Amy Acton | Ohio
@AmyActonOH | Physician and former state health director

Dr. Josh Green | Hawaii
@GovJoshGreenMD | Physician

U.S. HOUSE: MEDICAL DOCTORS

Dr. Ami Bera | California
@RepBera

Dr. Richard Pan | California
@DrPanMD

Dr. Raul Ruiz | California
@RepRaulRuizMD

Dr. John Cowan | Georgia
@DrJohnCowan

Dr. Rich McCormick | Georgia
@RepMcCormick

Dr. Kelly Morrison | Minnesota
@kellymorrisonmn

Dr. Bob Onder | Missouri
@BobOnderMO

Dr. Herb Conaway | New Jersey
@RepHerbConaway

Dr. Adam Hamawy | New Jersey
@HamawyForNJ

Dr. Maxine Dexter | Oregon
@RepDexterOR

Dr. John Joyce | Pennsylvania
@RepJohnJoyce

U.S. HOUSE: SCIENTISTS AND MATHEMATICIANS

Dr. Jasmine Clark | Georgia
@jasmineforga | Microbiologist

Daniel Biss | Illinois
@DanielBiss | Mathematician

Sean Casten | Illinois
@RepCasten | Biochemical engineer and scientist

Dr. Bill Foster | Illinois
@RepBillFoster | Physicist

STATE LEGISLATURES

Dr. Jarod Fox | Florida House
Infectious disease physician

Amanda Hemmingsen-Jaeger | Minnesota Senate
@Amanda_MNHouse | Former forensic scientist

[Brian S. Kim @itchdoctor]

People used to think we were making this stuff up. Now it’s everywhere! Peripheral neuroimmunology is a major field unto itself!

[Massimo @Rainmaker1973]

Scientists have created one of the most detailed 3D reconstructions of a human cell (eukaryotic cell) ever produced.

This groundbreaking model, often termed a "Cellular Landscape Cross-Section Through a Eukaryotic Cell," combines data from X-ray tomography, nuclear magnetic resonance (NMR), and cryo-electron microscopy to map molecular structures in extreme detail.

[SetPoint Medical @SetPointMed]

We’re excited to announce that Beth Israel Deaconess Medical Center completed its first #SetPointSystem procedure in Boston, expanding access to a new treatment option for adults with rheumatoid arthritis in the New England area.

Read the release: https://t.co/a8BjmrqOZX

[Alex Ritter, PhD @AlexRitterPhD]

I captured this video in my lab to show the power of medicines called T-cell engagers.

Left: T cells move in and out of a cancer tumoroid, largely ignoring it.

Right: Add a T-cell engager, and the T cells attack. Once they recognize their targets, they tear through the tumor.

[Zhi Huang @ZhiHuangPhD]

After submitting numerous #NIH R01 grants as an ESI (from not discussed to the 2nd percentile) and serving on multiple study sections, I've gradually learned a few things:
1. Despite the randomness, the NIH study section system is still relatively fair and rigorous in its review process.
2. Quantity does not lead to quality. Submitting many mediocre grants to increase the overall chance of success simply does not work. I only need one good proposal, and I should dedicate my attention to making it work. A grant is a proposal for what I aim to accomplish over the next five years. When I think about it clearly enough, the writing comes naturally. Preparing a grant really well also helps me sort things out for the future. It helps me correct my research direction upfront and saves government money.
3. None of the LLMs are helpful in writing grants (they can only be used to polish languages). They do not reason. They hallucinate. They fabricate. And we can tell it easily (in a study section).
4. Do real science, and people will appreciate it, sometimes.
5. I'm grateful to be in an environment where, despite the uncertainty in research funding, colleagues, mentors, and the department are always supportive. It really makes a difference.
6. Celebrate every small success, and always stay positive. 🙏

[Eric H Chang @changsbrain]

Noninvasive imaging of immune cell movement 🤩

[Michal Tal, PhD @ImmunoFever]

MICROSCOPY.
Making the invisible visible since 1590.

(Yes, those little white balls are actually immune cells flowing through the tinniest blood vessels! Imaged painlessly, non-invasively through the skin)

[Luke_Brown_91 @Luke_Brown_91]

China is replacing celebs with scientists, physicians, and inventors on billboards to inspire the next generation.

[Brian S. Kim @itchdoctor]

Congrats to Ayana Iijima from University of Tsukuba, a postdoc from our lab! She was awarded the most prestigious fellowship in Japan from the Japanese Society for the Promotion of Science (JSPS)!

Thank you to the JSPS for supporting her work and recognizing her unique talents. She will not disappoint as she is working on some of the most cutting-edge neuroimmunology!

https://t.co/sdA3suLvon

[Billy Hanlon @bhanlon15]

Feel awful for Kristaps

Anyone who lives with POTS knows how life-decimating it can be. Sending my best

[Elise Jenkins @Elise__Jenkins]

We did a thing! @foundersfund @OpenAI @coherenceneuro

[Jiamin Wu @JiaminWu7]

Our recent work presents a 1-gram wireless mesoscope for cortex-wide imaging at single cell resolution in naturally behaving mice, published in @Nature . It's interesting to see large-scale neural activities in multiple mice within a very natural habitat. https://t.co/Nbp67KFTDc

[Howitt Lab @HowittLab]

Excited to share our work in Science Immunology! Tuft cell signaling remodels the follicle-associated epithelium, influences M cell maturation, and promotes antigen-specific IgA responses. Led by @gabebarron. Thanks @DrRosenIBD & @jakob_moltke!
https://t.co/a8RLj4IKVn