Sijie Chen

ML researcher, Computational Immunologist, Postdoc@Stanford. Developing GenAI frameworks integrate multi-modal data- imaging, texts & multi-omics

[Michael Rabinovich @MikushRab]

Opus 4.8 just dropped and I ran it through our CAD tasks. 4.6 → 4.7 → 4.8 side by side.

The results are unexpected!

[Laurence Liang @LaurenceLiang1]

recently got interested in model pre-training for small models (100M-1B size)

still got a lot to learn, if anyone has recommendations about good resources for model pre-training, would love to hear!:)

[Skyler Miao @SkylerMiao7]

Something BIG is coming

[Sijie Chen @chensj16]

Всё выше

[Sijie Chen @chensj16]

i bet no

[DesertViewer88 @PhoenixGay29204]

@LiangChengMD I really appreciate everyone going after this fraud pointing out it is 1) gift authorship 2) self citations 3) impossible metrics and 4) forced authorship on papers but is @BrownUniversity going to do anything about it

[Zechen Zhang @ZechenZhang5]

1/ For nearly 350 years, science has communicated itself through one object: the paper. A linear narrative, frozen as a PDF, written for a human reader. We've come to treat that format as the medium of science itself.
It doesn't have to be. It's a historical artifact. 🧵

[向阳乔木 @vista8]

这篇华为的论文把我读笑了，真把人类组织的那套东西都搬给AI Agent了。

本周Huggingface第三热门的论文。

AI翻译解读见评论区

[金尘马 @jinchenma_ai]

难不成这就是大学不让学生用 AI 的原因？

一个本来没多难的概念，教材能写得像天书，老师也讲不明白，结果 AI 三句话就给讲明白了。

AI 让某些教材编写者和授课老师的水平直接原形毕露。

[Tae Seok Moon @Moon_Synth_Bio]

I came back to the United States, hearing about a very sad news: Craig Venter passed away today. He is a pioneer, successfully sequenced the first Human genome, and tried to create Synthetic Cells. We lost a giant in Science. RIP.
@JCVenterInst

[Sijie Chen @chensj16]

claude code down again? just failed to login but its status page looks fine

[Fabian Theis @fabian_theis]

1/ Annbatch unlocks terabyte-scale training of biological data in anndata 🚀
Check out our preprint here: https://t.co/vAjSo4S4GJ 📄
Grab the code on GitHub: https://t.co/c1DssS7peF
Massive shoutout to project leads @felix_f0097 and Ilan Gold for driving this home! 🧵👇

[Nature Careers @NatureCareers]

Jane Ying Wu, who took her own life, was cleared of wrongdoing by the US National Institutes of Health. Her family alleges that her employer destroyed her career. https://t.co/epe9i1VBkZ

[Sijie Chen @chensj16]

@Amank1412 this is the game i'd like to play

[no.mind @the_no_mind]

Martin Picard published one of the most important papers in modern biology in 2025.

Almost no one outside a small circle of researchers has heard of it.

The Energy Resistance Principle may explain disease, aging & energy crashes — from first principles.

Here’s the framework:🧵

[Sijie Chen @chensj16]

@ThibaultMean i'm not sure if `npx @anthropic-ai/claude-code` is still necessary today. since this was posted yesterday

[Sijie Chen @chensj16]

claude code went insane! downgrade to 2.1.83 and disable autoupdate to protect your usage quota!

[Sijie Chen @chensj16]

@JohnnyNel_ @AnthropicAI @claudeai 🙌

[Sijie Chen @chensj16]

Is it just me or Claude code still having the rate limit devouring bugs? I 'm on V2.1.89 with MAX 5x plan. token usage slopes indicate the rate is consumed as fast as it was before. Did Claude really fix this bug? @AnthropicAI @claudeai

[Sijie Chen @chensj16]

@NathanielC85523 @AnthropicAI @claudeai any ideas on how to fix it?

[Sijie Chen @chensj16]

@nextflowio i ask claude code to build these workflows. so i don't learn it

[Iris Hayes @irisneural]

🚨BREAKING: You can now run Claude Code for FREE.

No API costs. No rate limits. 100% local on your machine.

Here's how to run Claude Code locally (100% free & fully private):