Thank you @carlzimmer and @nytimes.
A new study led by @EgliDieter's lab at @Columbia, co-authored by Nucleus Chief Clinical Officer @TreffDNA, demonstrated near-100% efficiency in human embryo gene editing — a milestone that may redefine what's possible in preventing inherited disease.
Building on this work, Nucleus is proud to fund the next phase of research focused on further advancing this technology toward clinical use.
We believe families deserve access to every tool modern genetics can offer. Advances like this may one day offer new hope to families facing inherited genetic disease when few options exist.
We're honored to support the scientists helping make that future possible.
Genetic engineering in human embryos is here.
Today, in a world first, @Columbia and @nucleusgenomics announce high-efficiency editing of human embryos.
The study, led by Dr. Dieter Egli's lab at Columbia University, with Nucleus Genomics’ Dr. Nathan Treff as a senior co-author, achieved editing efficiencies of up to 100% at targeted loci. Simultaneously, we showed no detectable editing-induced chromosomal abnormalities and low off-target activity.
In other words, this is the closest we've come to practical, high-precision gene editing in human embryos.
We are also excited to announce we will be funding and participating in the next phase of this research, alongside Columbia and Dr. Egli.
We see ourselves as a natural pathway for eventually bringing technologies like this into clinical care as part of a broader genetics platform — a full "Genetic Optimization" stack.
@nytimes broke the news in what is a historic moment for Genetic Optimization. See story in thread.
One year ago, we launched Nucleus Embryo — the most advanced embryo analysis available.
Our belief was simple: one of the most important decisions of your life deserves to be made with all the information modern science has to offer.
In the year since launch, Nucleus Embryo has become one of the fastest-adopted technologies in modern fertility care. It's now available in IVF clinics across almost every U.S. state and more than 165 clinics globally.
Find out why more parents are choosing Nucleus Embryo below.
One year ago today, we launched Nucleus Embryo. The biggest leap in embryo screening since IVF began. At the time, IVF patients were choosing their future baby randomly — with no health information.
Today, Nucleus Embryo is one of the fastest-adopted technologies in modern fertility care.
In just 12 months, we've expanded to 165+ fertility clinics globally, kicking off an international patient-led movement on genetic optimization.
What a privilege it is to serve our patients, and help couples all over the world build generational health.
Learn more below.
Nucleus is now available to patients at @SCRCivf, one of the most trusted fertility networks in California.
For decades, SCRC has helped thousands navigate one of the most emotional and important journeys of their lives: building a family.
We’re proud to partner with @DrMarkSurrey, @DrCAlexanderFer, and the entire SCRC team to bring more advanced genetic insight into IVF care.
We have an exciting video with NothingButTech coming soon!
@nbtjacklyn dives into Nucleus and the advanced genetic technology we bring into IVF to help families reduce health risks for their future children — and give them the best possible start in life.
See a sneak peek below.
Genetic Optimization is having its moment. I'm so happy to see this amazing tech reach so many people. Its gone through a transformation that many people are now just starting to realize. Congrats to Kian and team!
https://t.co/SKTGh8lGwW
Kian Sadeghi, CEO of Nucleus Genomics, wants to help parents design their own babies, from height to IQ to personality traits. What happens to humanity when we have the power to tamper with life’s formula?
Thank you @TuckerCarlson for inviting me on.
A year ago, Genetic Optimization didn’t exist. Now, parents around the world are using it to have their best baby.
I deeply believe genetics is one of the greatest tools for preventative medicine and will help define the 21st century.
Today, Bloomberg @business announced the largest deployment of genetic optimization ever by @nucleusgenomics.
Tens of thousands of patients across 160+ clinics in India and the Middle East will now have access to our advanced embryo analysis through joint ventures with @IVFIndira — the second largest IVF network in the world — and Abu Ghosh Fertility Group.
Genetic optimization is rooted in a universal parental instinct: giving your child the best possible start. That demand is especially strong in India and the Middle East, driving our expansion.
This is a milestone for IVF patients everywhere — and for genomics. After two decades of work since the Human Genome Project, we’re realizing its promise as the ultimate tool for preventative healthcare.
We’re proud to be building this alongside Indira’s team of over 3,000 specialists, Dr. Hilal Abu Ghosh and his team, and the patients we will have the pleasure of working with.
Read the full story in thread.
We’re announcing our largest clinic expansion to date.
Nucleus is now working with @IVFIndira, the second largest IVF network in the world, and the Abu Ghosh Fertility Group — bringing genetic optimization to 160+ clinics across India and the Middle East.
These collaborations mark the largest deployment of genetic optimization ever, with tens of thousands of patients now being able to access advanced embryo analysis.
Both India and the Middle East carry one of the highest chronic disease burdens, with conditions like heart disease, diabetes, and metabolic disorders shaping the health of hundreds of millions. Not just today, but across generations.
Now, with Nucleus, parents undergoing IVF can build generational health — lowering the genetic risk for these conditions in their future babies.
We’re proud to continue our mission in bringing generational health to everybody, now with the help of Indira’s 3,000 specialists and Abu Ghosh’s exceptional team.
Read the full story in Bloomberg @business below.
Perry Ellis announced Miami Dolphins sponsorship alongside the launch of their collection with the team’s quarterback Tua Tagovailoa.
🔗: https://t.co/cyAnKp8rEO
Ya boy is back on @Jeopardy tonight.
Pretty sure we’re preempted by Monday Night Football, so bring a Red Bull for J! After Dark. #CheckYourLocalListings