Chiarle lab

Official account of Roberto Chiarle's laboratory @BostonChildrens and @unito

[Chiarle lab @chiarlelab]

Not easy to encompass the growing importance of #ALK in cancers and the progress in treating ALK+ tumors, but this Review might help @chiarlelab @NatureRevCancer @BostonChildrens @unito
https://t.co/I8GHcvtIkg

[Kathleen Helen Burns @KathleenHBurns]

These experiments reveal the full extent of DNA damage caused by L1 expression. The retroelement that built our genome wreaks havoc, too. Powerful implications for cancer biology. Beautiful collaboration with Alice Lee’s and CZ Zhang’s labs. @DanaFarber

[AmbrogioLab @AmbrogioLab]

Our latest publication online now! https://t.co/uEMyfMV8jR @NatureComms
Amazing team work @lab_santamaria @MJNokin @BiagioRicciutMD @DrMarkAwad @NadalErnest @cereda_lab

[Chiarle lab @chiarlelab]

@chesscom No

[Kathleen Helen Burns @KathleenHBurns]

Very exciting opportunity to join the faculty ⁦@BWHPath⁩ :
bwh pathology professsor opening - Google Search ⁦⁦ https://t.co/6iHcbMlxtV

[Chiarle lab @chiarlelab]

Fantastic collaboration with @maddanilo and the @genentech team for our review on SHP2 just out @CD_AACR
https://t.co/QlWWju0BxJ

[AmbrogioLab @AmbrogioLab]

Thanks a lot @CICancer_com for hosting the first RAS Initiative Europe event #TargetingRAS, we enjoyed three days of amazing science! @KRASKickers @FredNatLab #KRAS

[Chiarle lab @chiarlelab]

Check out our paper on @ScienceTM that deciphers how to overcome ALK TKIs resistance in ALK+ lymphoma by targeting the CCR7-PI3Kgamma pathway. Congrats to all the talented scientists that helped the work! It's on the cover! @BostonChildrens @unito
https://t.co/ICoZUSftVW

[Peter J Park @peter_j_park]

Many others contributed, including many current and former members of my lab, especially @isidrolauscher. Taek from the Roberto Chiarle's lab (@chiarlelab) performed the experiments, my illustrious collaborators Steve Elledge and David Pellman provided insightful comments.

[LUNGevity Foundation @LUNGevity]

It is such an honor for us to partner with
@ALK_Research & @ALKLungCancer to fund research most meaningful to the ALK community. Thank you, @DrMarkAwad, @IbiayiMD, @chiarlelab, Dr. Raphael Nemenoff, Dr. John Iafrate, and @LironBarPeled for your commitment to research #LCSM

[BCH Innovation News @BCH_Innovation]

A caution on CRISPR in @NatureComms, and the suggestion that base editing and prime editing may be safer from @jianli_tao, Roberto Chiarle, et al. https://t.co/zvFQM0A8T4 #mobileelements #jumpinggenes

[Chiarle lab @chiarlelab]

Our work on LINE-1 insertions at CRISPR editing sites is already out! Congratulations to Jianli Tao (@jianli_tao) and Qi Wang (@flying_gene) @chiarlelab. Many thanks to our collaborators from @KathleenHBurns to help to make it possible.

[Ross Cloney @rosscloney]

And @jianli_tao @flying_gene & co in @chiarlelab at @BostonChildrens @harvardmed explore the frequency & mechanism of LINE-1 insertions at #CRISPR editing sites

https://t.co/Xcprc2cZrD

[Lecia Sequist, MD, MPH, FASCO @LeciaSequist]

Jonathan Riess says that the future of immunotherapy in mutation-driven lung cancer is vaccines - I hope this pans out, for patients' sake! Exciting ongoing trials in both EGFR and ALK #TTLC22

[Chiarle lab @chiarlelab]

*Karaca-Atabay et al.

[Chiarle lab @chiarlelab]

Nice comment about our recently published paper in @BloodJournal from Karaka-Atabay et al. Thanks to Dr. Ryan Wilcox for highlighting our work.

[Blood Journals Portfolio @BloodPortfolio]

Getting ALK inhibitors SHPshape https://t.co/RR3KOT6dvR

[Chiarle lab @chiarlelab]

Nice comment about our recently published paper in @BloodJournal from Karaca-Ataby et al.@atabay_karaca Thanks to Dr. Ryan Wilcox for highlighting our work.

[Blood Journals Portfolio @BloodPortfolio]

Getting ALK inhibitors SHPshape https://t.co/RR3KOT6dvR