Chris Shepherd

Oncology drug development in biotech. Pro-EU. Francophile. Home is Castelsagrat, Tarn-et-Garonne. Views my own 🇬🇧🇨🇵

[Stephen V Liu, MD @StephenVLiu]

FDA grants accelerated approval for datopotamab deruxtecan, anti-TROP2 ADC, for #EGFR mutant NSCLC after prior TKI and chemotherapy. An active agent, based on TROPION-Lung01 and 05. Important toxicities include stomatitis and ocular effects.

https://t.co/oxQKdPFPY8

[Chris Shepherd @ChrisJ_Shepherd]

@gdpops1950 @AP Who walked away from the JCPOA agreement without a clear plan to replace it? And then subsequently piled on a bunch of new sanctions that tanked Iran's economy. This is a cycle of mistrust and escalation and both the US and Iran are to blame.

[Chris Shepherd @ChrisJ_Shepherd]

@PTarantinoMD Not sure I'd want to B2B Topo1i payloads given resistance to payload is more likely...I'd go taxane and then if good PFS, I'd go back to tras-derux

[Chris Shepherd @ChrisJ_Shepherd]

@DonaldJTrumpJr There is no Stage 5 cancer. Cancer is staged from 1-4. So Jill didn't miss a stage 5 cancer. It appears he has been diagnosed with stage 4 disease but this isn't uncommon - sometimes there are non specific symptoms.

[Chris Shepherd @ChrisJ_Shepherd]

@harald_b @BBCLondonNews No. It wasn't. Petrol and diesel cause bad air. But air also moves with the wind..and bad air from the continent can accumulate over London...and combined with other bad air can equal really bad air. We covered this topic in school.

[Chris Shepherd @ChrisJ_Shepherd]

@harald_b @BBCLondonNews No....it means that the air that's arriving over the London area is coming up from the continent....it happens sometimes. Watch the weather forecast.

[Chris Shepherd @ChrisJ_Shepherd]

@PTarantinoMD If you look at https://t.co/EZSDw43JAH it would seem the additional benefit of CTx may be minimal, but for a young premenopausal lady, probably worth a discussion of risk/benefit.

[Chris Shepherd @ChrisJ_Shepherd]

@stolaney1 But need to see overall PFS and OS in SERENA6 (ESR1m in ctDNA - early switch to cami + CDK4/6) vs. switching to/sequential elacestrant at progression on CDK4/6 + NSAI and + ESR1m?

[Chris Shepherd @ChrisJ_Shepherd]

@GoogleSnaky @MaiLynn60791245 @PeteButtigieg Don't get me wrong. Everyone should vote. But it's the misinformation. The so called 'Freedom of Speech' that gets filtered through social media algorithms so it's 'tailored' for you, such that the narrative they want you to hear is the one you hear.

[Chris Shepherd @ChrisJ_Shepherd]

@MaiLynn60791245 @PeteButtigieg What???? You'd rather give money to a corporation to serve shareholders and pay massive bonuses than spend time looking at where your taxes are spent?? Literally, I have no words.

[Chris Shepherd @ChrisJ_Shepherd]

@PantsStanky @AmyMcGrathKY What utter ignorant crap

[Pashtoon Kasi MD, MS @pashtoonkasi]

#GI25🎤drop #NEST🪺🙋🏻‍♂️🙌🏽

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✅NO RECURRENCES📅!

💡Neoadjuvant immunotherapy keeps delivering!

👉🏽Patients with MSS🧊NOT just MSI-High🔥colorectal #cancer.

Goal is to👏🏾*CURE*👏🏾more patients.

🔜Phase2/3
@OncoAlert @ASCO

[Chris Shepherd @ChrisJ_Shepherd]

@EmilyDu06328376 @BBCNews No it's not...but there are 8 organs listed

[Chris Shepherd @ChrisJ_Shepherd]

@RADrebel43 @MaryLTrump You can't argue with stupid

[Chris Shepherd @ChrisJ_Shepherd]

@PhilHK747 @JamesMelville You'll pay more tax than this pretty much anywhere else in Europe. UK is still a low tax developed western country.

[Paolo Tarantino @PTarantinoMD]

The results of SONIA are out on @Nature. 1L use of palbo did not improve PFS over 2L use, but led to more AEs & costs. An evolving treatment landscape challenges its interpretation— yet it shows that sequencing trials are possible. Congrats to the authors! https://t.co/XozXKro2sx

[Chris Shepherd @ChrisJ_Shepherd]

@benhabib6 @JonAshworth If national debt is out of control, it wasn't caused by the Labour government in the first few months of being in government.

[Chris Shepherd @ChrisJ_Shepherd]

@smthngnope @benastonx It's unimaginable to me that people with these views actually still exist.

[Chris Shepherd @ChrisJ_Shepherd]

@drsarahsam In France, if you have cancer, a nurse visits your home weekly to take bloods and deliver your medications/health supplements. End of life care is either delivered in a hospice or a hospital bed is delivered to your home where palliative care is provided.

[Chris Shepherd @ChrisJ_Shepherd]

@PTarantinoMD @DanaFarber @DFCI_BreastOnc Didn't your first badge say Pablo?