Craig Dent

Postdoc @ Max Planck Institute for Plant Breeding Research

[SKB Lab @SKBLab]

Happy to share our latest work to define the features that explain splice-site choice in eukaryotes! Here we have empirically quantified splice-site usage across individuals in Arabidopsis, Drosophila and Humans and attempted to infer patterns (1/10)

https://t.co/yuW9HtjnHo

[Avilash Singh Yadav @Morpholosophist]

Our review with @SKBLab @GATCLab and Alok Sinha on plant temperature sensing is now in Science (https://t.co/Kx59fyhM5Z). Special thanks to @weillinstitute @RoederLab and my alma mater @MonashUni @Monashbio (1/2).

[Xiao Dong @justdx0713]

1/
🚨 My first PhD preprint is out on bioRxiv!
We show how tiny mutations—point mutations and kb-level indels—can shape the massive structure of Arabidopsis centromeres.
📄 Read it here: https://t.co/YshezMW5cQ
🧵 A short thread 👇

[Schneeberger lab @LabSchneeberger]

📢 Excited to share our work out now in @Nature! 📢

We present the phased pan-genome of the European tetraploid potato, based on 10 historical cultivars representing 85% of European potato diversity.

Learn more below!

🔗 https://t.co/JNuZEMWKxQ

1/7

[Craig Dent @ciden13]

Gratitude to co-firsts Stefan and Aiswarya; a pleasure to work with both across years and continents. To James and Aaryan for their extensive follow-up work. @SouravBiotech, Jordy, and other authors for their efforts. And to @SKBlab for weaving it all together! (4/4)

[Craig Dent @ciden13]

https://t.co/bsIUaagNHM

New preprint from my time at @MonashBiol. We measured RNA splice-site-usage across populations in plants/flies/humans. We GWAS'd every promising splice site. No silver bullet, but all signs pointed towards sequence variation around splice sites. (1/4)

[Craig Dent @ciden13]

I hope this can be a useful ref for intuition/engineering of splice sites +
Anyone with a favourite gene in At, Dm, or Humans check out Supp. tables 3-5; might be natural variation in splice sites affecting your trait of interest & we might be close to the causal variant. (3/4)

[Schneeberger lab @LabSchneeberger]

Somatic mutations introduce new phenotypes that are often used in modern plant breeding. Our work now provides insights into somatic mosaicism at the cellular level. We show that in trees, most mutations are specific to cell layers of the meristem.
https://t.co/peOLiUjvnk

[SKB Lab @SKBLab]

Latest preprint led by @GATCLab in collaboration with Hongtao Liu, @AriSadanandom, Emanuel Rosonina, Ram Yadav, @dopaminator on epigenetic silencing caused by repeat expansions (1/4) https://t.co/3QehoJmxnT

[Craig Dent @ciden13]

SpliSER Version 0.1.8 up on Github
https://t.co/dZe34MwGxr
A bug fix, some extra details on how to generate stranded splice junction .bed files, and a template file for diffSpliSER analysis.

[Genevieve Roch-Decter, CFA @GRDecter]

ChatGPT launched just 5 days ago and already crossed 1 million users.

Here’s what you should know about one of the most disruptive technologies ever created.

🧵👇

[Isin Altinkaya @IsinAltinkaya]

How can #ChatGPT help you use R?

Help you...
-> Plot your data?
-> Transform it?
-> Or just have a casual chat about the meaning of life while you look like you are working?

A tutorial (and an experimental R wrapper
gptchatter):
https://t.co/XYiMhbWUH8

#DataScience 1/n

[SKB Lab @SKBLab]

There has been the observation that cry2 mutants flower late and this late flowering is enhanced at lower temperature. Here is a possible mechanism. It started a nice on going collaboration with Hongtao Liu lab! Well done ⁦Zhiwei & @ciden13⁩ (1/3) https://t.co/O3b21gySGC

[Craig Dent @ciden13]

@TIPollock @DrTeethAl @DPHocking Congrats Tahlia 😃

[Craig Dent @ciden13]

@RosGleadow @MonashBiol Congrats Harry!

[Craig Dent @ciden13]

@Zahra_F_Islam @FVASunimelb @HangweiHu @FertiliserHub Congrats Zahra!!

[Craig Dent @ciden13]

@fcamus @NERCscience @uclbiosciences Congrats Flo, that is fantastic news!!

[Craig Dent @ciden13]

@jumpingenes @SKBLab @Monash_Science @MonashBiol Thanks Miloš, that means a lot!

[SKB Lab @SKBLab]

(1/2) Very pleased to see this put now in print. We suggest to look at individual splice-sites while analyzing splicing, especially if one is interested in the regulation of splicing…@MonashBiol @ciden13 @GATCLab @d_r_powell https://t.co/pdYSJsjP1K