Circulation Research

Circulation Research is an AHA journal focusing on basic science & translational cardiovascular research.

[Circulation Research @CircRes]

Dasgupta et al found #DNM2 binds #DRP1 causing #mitochondrial fission. #Epigenetic & transcriptional increases in DNM2 in #PAH drive #proliferation via regulating cell cycle. Learn more at https://t.co/Bhb43v8cBQ
@Asish_Dasgupta @drstephenarcher @DrHindmarch @Limapda

[Circulation Research @CircRes]

Cai & colleagues found that delivery of healthy #mitochondria using #nanovesicles attenuates elastase-induced #AAA. Learn more at https://t.co/mlU6OfXcAD

[Circulation Research @CircRes]

Zheng & colleagues found #exercise training can leave a long-lasting protective #metabolic imprint on the heart. Learn more about a potential new therapy for preventing pathological #CardiacHypertrophy at https://t.co/J4NsUeb2nU

[Circulation Research @CircRes]

Check out the latest review in the May 22nd issue of @CircRes by Kocx & colleagues "Right-#Heart Diastology, Where Are We Now? " at https://t.co/uiGoOjPu0O

[Circulation Research @CircRes]

Pan & colleagues detected #micro(nano)plastics in human #heart tissue, & higher tissue levels were associated with greater #fibrosis. Learn more about a possible role for plastic particles in adverse cardiac remodeling at https://t.co/cZ0PWeszM4

[Circulation Research @CircRes]

Larcher & colleagues identified a subset of cardiac #fibroblasts that express the receptor for the fat-derived hormone #leptin & play a key role in post-#heart attack scarring. Learn more at https://t.co/0whDiZa0qC
@NunoCamboa @SimonSerio @PaolaCattaneoIT

[Circulation Research @CircRes]

Huang et al found a critical driving role of endothelial #NOX1 activation in the development of #obesity & #metabolic syndrome Learn more at https://t.co/cFCUF3MU9z
@HuaLinaCai @LabFreed

[Circulation Research @CircRes]

Dionísio et al found that #macrophage specific deletion of the glycolytic rate-limiting enzyme #PKM2 leads to stabilization of #atherosclerotic lesions but not difference in plaque size. Learn more at https://t.co/R8b0pF73Zp
@l_tomas01

[Circulation Research @CircRes]

Chacon-Barahona et al studied how blood markers of #metabolism associate with #RV function in people with #PH https://t.co/8OUyVYuY8h
@JaneALeopold @FrantzDrBob @bborlaugmd @DebbieKwonMD @ebrosenzweig @SteveMathaiMD @kokopark13 @mmukherjeemd @ChrisJellisMD @rrvdpool

[Circulation Research @CircRes]

Meral et al found cell type-resolved #transcriptomics reveal that diastolic dysfunction is linked to a reversible shift in #fibroblast states, driven by #mineralocorticoid receptor signaling. Learn more at https://t.co/vzydjvWSLQ
@MeralDavid

[Circulation Research @CircRes]

@CircRes May 22nd Issue is Out! https://t.co/IiX6g6rOKd

Cover: Artistic visualization of Fb state transitions, illustrating the shift from homeostatic to activated profibrotic states during HF driven by mineralocorticoid receptor signaling.

[Circulation Research @CircRes]

5/5 EVs-Mediated Intracardiac Crosstalk Mitigates Doxorubicin-Induced Cardiotoxicity by Wang et al https://t.co/jjP4MZcDI4

[Circulation Research @CircRes]

1/5 New @CircRes podcast #DiscoverCircRes https://t.co/DOkUWjuSd7! @StHilaireLab chats with Drs. Noah Perry and @mete_civelek about their study Female-Biased VSMC GRNs Predict MYH9 as Regulator of Fibrous Plaque Phenotype https://t.co/CLeVCCBwmz

[Circulation Research @CircRes]

4/5 A Recellularized Humanized Bioengineered Bi-Atrial Model for Arrhythmia, Biological Pacemakers, and Optogenetic Studies by Ghiringhelli et al https://t.co/bS3yrmYMsG

[Stroke AHA/ASA @StrokeAHA_ASA]

📢 #Stroke Bridge Seminar: Normobaric Oxygen in Stroke: From Experimental Insights to Clinical Perspectives, with Ke Jian "Jim" Liu, @AneeshSinghalMD, & @Chenhsbbb.
🗓️ May 26, 12:00–1:00 PM PDT | 19:00–20:00 UTC
📎 Register: https://t.co/TtvpUcHwy9

[Circulation Research @CircRes]

Perry et al found #MYH9 plays a key role in shaping fibrous, more stable #atherosclerotic plaques through sex-specific regulation of #VSMCs https://t.co/2QQzKMJKCK
@mete_civelek @Vascular_Prot @molvascular_TUM @KaikkonenLab @InnovatieHester @DiezBenavente

[Circulation Research @CircRes]

Zhang et al created a set of novel reporter mouse models that precisely label #ECs, & they provide robust genetic tools to reveal the developmental origins & heterogeneity of #VECs. Learn more at https://t.co/o3MysqKuBO
@TheZhouLab

[Circulation Research @CircRes]

Wang & colleagues found cardiomyocyte-derived #EVs post exercise were enriched for a cardiac-specific protective #piRNA. Learn more about potential therapeutic strategy for #doxorubicin-induced cardiotoxicity at https://t.co/G0Jbnflhrd