Esta imagen es muy típica de un tipo concreto de leucemia aguda ¿Qué hallazgos no son
sugestivos de esta entidad?
a. Reacción de mieloperoxidasa muy intensa
b. Marcados rasgos de mielodisplasia
c. Núcleos en hachazo o partidos
d. HLA-DR y CD34 negativos por citometría
This mast cell.. very casually releasing its gorgeous granules on the surrounding dysplastic granulocytes
I think it’s trying to fight the MDS… 🥷 or maybe it’s just pretending to be good 😈
#hemepath#MDSSM
Plasma cells with Auer-rod-like inclusions in a patient with MGUS and acute myeloid leukaemia with NPM1 mutation |British Journal of Haematology | Wiley Online Library https://t.co/Gr4lhdUhlw
β1 = transferrin
β2 = β lipoprotein (LDL)
Now look at the image again. The albumin is ⤵️, α2 and β are ⤴️
It's either loss (or underproduction) of albumin and an ⤴️ production of lipoproteins and α2 components!
Can you join the dots and make the diagnosis?
5/16
A 63-year-old man with a history of follicular lymphoma presented with 2 weeks of fatigue and 3 days of dyspnea. On physical examination, he had decreased breath sounds at the base of both lungs. 1/3
📍 Lanzamiento del proyecto ALMA sobre inteligencia artificial y medicina personalizada en enfermedades hematológicas, impulsado por el #ISCIII y @CDTI_innovacion en el marco del #PERTE_SaludDeVanguardia.
📰 Más información en #NoticiasISCIII ➡️ https://t.co/PHTnNb5pxg