Chinmay Shukla

Interests: Genetics, Drug Development, Machine Learning | Before: @iitmadras, @Harvard with @RafaLab | All views are personal

[Shane Parrish @shaneparrish]

Waiting for the right time is seductive.

Our mind tricks us into thinking doing something now is hard but if we wait it will get easier.

Most of the time, waiting only makes things harder.

The right time is now.

[Chinmay Shukla @cjshukla]

Heartbreaking 💔

#sicklecell #healthinequalities #biotwitter

https://t.co/8hm0ddmSAu

[Chinmay Shukla @cjshukla]

Interesting look back as FDA approves 100th mAb

- About half the approved mAbs are for one of 8 targets.
- Though 1st approval in 1980s, majority in 2010s i.e., ~30 years after

What does this say about today's new modalities? #biotwitter #Biotechnology

https://t.co/m6el4Ev0vO

[Shane Parrish @shaneparrish]

When you can't decide between two choices, pick the one with short-term costs and long-term benefits.

[Randall Munroe @xkcd]

Types of Scientific Paper https://t.co/crpSNv9Er5

[CRISPR MEMES @CrisprMemes]

jumping on that bandwagon like it's CRISPR in 2014

[Morgan Housel @morganhousel]

A good reading strategy is to be willing to try any book that looks even slightly interesting but be ruthless about quitting books that aren't working for you, even after a page or two.

Wide funnel, tight filter.

[XKCD Comic @xkcdComic]

Eradication https://t.co/onXiqGVD9r https://t.co/zKHa00wDVF

[Morgan Housel @morganhousel]

Dogecoin is now worth more than Ford.

Amazon Prime now has more members than all but seven countries have citizens.

What a time.

[Shane Parrish @shaneparrish]

Being busy isn't the same thing as adding value.

[Tim Urban @waitbutwhy]

We think a lot about those black lines, forgetting that it’s all still in our hands.

[Chinmay Shukla @cjshukla]

Making things simple is much harder than making things complicated.

#ideas #decisionmaking

[Shane Parrish @shaneparrish]

We undervalue simple ideas and overvalue complicated ones.

Complicated doesn't mean correct. Simple doesn't mean simplistic.

[10-K Diver @10kdiver]

1/

Get a cup of coffee.

In this thread, I'll show you a simple way to work out a fair price to pay for a wonderful business.

[Chinmay Shukla @cjshukla]

Progress happens slowly at first and all at once later #newmodalities #biotech

[Simone Fishburn 🎗️ @FishburnSimone]

New modality drugs are making it to market at an increasing clip. ~30 in last 5 years, ~50 in registrational trials. Different factors for different modalities, but some of the hurdles are the same. @biocentury. https://t.co/Luz0zSiRtN

[Brad Loncar @bradloncar]

Burnt to a crisp:

$EDIT -60%
$CRSP -50%
$NTLA -44%
$BEAM -46%

(Since Jan highs)

[Chinmay Shukla @cjshukla]

Having grown up in the aftermath of these policies, I agree with the general idea behind this piece.

[Arvind Panagariya @APanagariya]

Read how the pursuit of self sufficiency morphed into investment licensing, import controls, small-scale industries reservation and price and distribution controls, holding the Indian economy back for four decades.

[Shane Parrish @shaneparrish]

The novice sees the answers.
The professional sees the complexity.
The master sees the simplicity.

[Paul Graham @paulg]

When startups are doing well, their investor updates are short and full of numbers. When they're not, their updates are long and mostly words.

[Morgan Housel @morganhousel]

Best explanation of the past few years:

https://t.co/W8dAsa2g2r

[Chinmay Shukla @cjshukla]

From 2016 to 2020, the market capitalization of publicly listed Chinese companies developing innovative drugs rose from $1 billion to $217 billion, according to McKinsey. In 2019, the first China-developed cancer treatment was approved in the U.S.

https://t.co/ovWtcDXyom