Ondine Cleaver

Molecular biology, development, cell renewal & differentiation, stem & progenitor cells. Center for Regenerative Science & Medicine. Meet me in the sky.

[Ondine Cleaver @cleaverlab]

Calling all vascular biologists! Join us for cutting edge science at #Angioscience26 in gorgeous Seeon, Bavaria.

Awesome speakers, intimate setting, many talks from abstracts. Deadline June 15th to register! https://t.co/jqmcd7GnGq

[Ondine Cleaver @cleaverlab]

Thank you to @NanionTech for your support of #Angioscience26!

[Nanion Technologies @NanionTech]

𝗧𝗵𝗲 𝗳𝗶𝗿𝘀𝘁 𝗣𝗮𝘁𝗰𝗵𝗹𝗶𝗻𝗲𝗿ᵐ 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗚𝗿𝗮𝗻𝘁 𝗶𝘀 𝗵𝗲𝗿𝗲!

What if patch clamp could be fast and simple, while keeping you fully in control?

Many ion channel experiments are delayed by limited access to patch clamp equipment, resources, or expertise.

Patchlinerᵐ offers a simpler way of doing patch clamp, helping researchers accelerate experiments and record multiple cells simultaneously.

This grant is designed to help researchers explore ion channel biology, biophysics, target validation, and assay development.

The selected recipient will receive:

✔️ Patchlinerᵐ in their lab for 6 months
✔️ Full training
✔️ Consumables for the research project
✔️ Expert assay and application support

🗓️ 𝗔𝗽𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻𝘀 𝗼𝗽𝗲𝗻: July 2026

Want to be the first to receive updates about the grant?

𝗥𝗲𝗴𝗶𝘀𝘁𝗲𝗿 𝘆𝗼𝘂𝗿 𝗶𝗻𝘁𝗲𝗿𝗲𝘀𝘁 𝘁𝗼𝗱𝗮𝘆: https://t.co/ijiYavIuhi

#PatchClamp #Electrophysiology #IonChannels #APC

[Ondine Cleaver @cleaverlab]

Thank you Hao! Steve Spurgin's awesome work looking at how endothelial cells respond differently to different types of flow!

[Hao Yin @HaoYin20]

Glenn-Fontan procedure is essential to treat Single-ventricle congenital heart disease

However, Glenn surgery▶️loss of pulmonary arterial flow pulsatility & pulmonary vascular malformation

How?🤔

Here, in this fresh-on-the-shelf @JCI_insight paper
Dr. Ondine Cleaver lab @cleaverlab😎

👉Profiles biophysical alterations of right pulmonary artery flow in a rat model of Glenn surgery
Simultaneous drop of 1⃣Velocity 2⃣Pressure 3⃣Circumferential stretch

👉Dissects the transcriptomes of pulmonary arterial endothelial cells with Pulsatile vs Non-pulsatile
1⃣Flow/Shear
2⃣Pressure
3⃣Stretch

Several intriguing findings
👉Puls. Pressure & Stretch ⏬Proteasome ⏫mTOR
👉Puls. Stretch ⏫Notch HedgeHog
👉Puls. Flow & Pressure ⏫TGFβ
👉No impact on arteriovenous differentiation

👉Mechanosensitive, Dimension-specific #Angiogcrine!!🤩

A critical in vivo relevance
Puls. Stretch-induced endothelial PDGFB maintains Pulmonary Arterial (not Venous) Smooth Muscle Cell Mass🤠

Does ECMO non-pulsatile flow cause similar mural-weakening issues?

https://t.co/EW7mFxFB8p

[Ondine Cleaver @cleaverlab]

Join us for the fantastic Kloster Seeon Angioscience meeting next September in beautiful Bavaria! From vascular formation to maintenance to angiocrine support of tissues.
Register now!

[Ondine Cleaver @cleaverlab]

Re-upping! Hoping you can join us!

Calling all cardiovascular biologists! 🫀
Registration open.

[Ondine Cleaver @cleaverlab]

🚨 SAVE-THE-DATE 🚨

SEEON ANGIOSCIENCE! Fantastic, long-running meeting on Development & Maintenance of the Vasculature.

🗓️ Sept 2026
🌍 Bavaria, Germany

Registration open! Join us!
https://t.co/OUFntridXS

[Ondine Cleaver @cleaverlab]

Please RT! :)

@HellmutAugustin
@ralfhadams
@holger_gerhardt
@BenjaminHogan13
@NicoliLab
@PetrovaLab
@bikohcello
@LabPhng
@potente_michael
@RuiBenedito_
@pipsa_saharinen
@YaleCardiology
@EVB_Org
@DonIngber
@vascbiol
@BMVBSoc

[Ondine Cleaver @cleaverlab]

🚨 SAVE-THE-DATE 🚨

SEEON ANGIOSCIENCE! Fantastic, long-running meeting on Development & Maintenance of the Vasculature.

🗓️ Sept 2026
🌍 Bavaria, Germany

Registration open! Join us!
https://t.co/OUFntridXS

[Ondine Cleaver @cleaverlab]

@HaoYin20 Thanks so much Hao!! Missed your tweet! 🙏

[Developmental Biology @Dev_Bio_Journal]

#DBfeature 🌊

Hedgehog signaling is required for larval muscle development and larval metamorphosis of the mussel Mytilus coruscus

by Yi Tang, Yu-Qing Wang, Yi-Feng Li et al
https://t.co/1Hss9ACY9W

[Ondine Cleaver @cleaverlab]

Thinking about Grad School? The @SocDevBio is here to help!

Deadline August 26th, 2024! Apply NOW
https://t.co/i5i9iEzIkJ

#GradSchool #DevBio

[Ondine Cleaver @cleaverlab]

@melmelwrites having the same exact problem. Hundred dollar voucher. But I don’t even find a number to call.

[Ondine Cleaver @cleaverlab]

@FlyFrontier You have cancelled my flight today. I need to get to NYC TONIGHT. Please help.

[Eric Betzig @Eric_Betzig]

#cellbiology #bioart The actin #cytoskeleton (green) is linked to a variety of transmembrane proteins through alpha-actinin (magenta), with such linkages being particularly dense in membrane ruffles and filopodia. As seen at 3 frames/min for 8 min by linear and non-linear structured illumination microscopy (97 and 60 nm resolution, respectively). https://t.co/bYtG5sl0Te

[NAVBO @vascularbiology]

Deadline is TODAY - July 19!

REGISTER for VASCULATA 2024

Plan to attend Vasculata 2024 in California, July 22-25, 2024 at Stanford Cardiovascular Institute

Details & Registration: https://t.co/FnmD7uB1sR

[Developmental Biology @Dev_Bio_Journal]

#DBfeature

Normal table of embryonic development in the Anji salamander Hynobius amjiensis (Hynobiidae)

by Zhihao Cao, Ruiyang Guo, Longhui Lin et al
https://t.co/y4JZuQSzzO

[𝘿𝙧. 𝘾𝙧𝙮𝙨𝙩𝙖𝙡 𝙍𝙤𝙜𝙚𝙧𝙨 ≽(◕ ᴗ ◕)≼ 🐥🐸 @RogersLabUCD]

Hoping to have more discussions with #DevBio ⁦@SocDevBio⁩ folks about their responses so we can make the field and society more inclusive. Check out these community poll results from #2024SDB - via #Whova event app

[@LaBonneLaB @labonnelab]

Ken is more than Kenough! #2024SDB was a FANTASTIC meeting! Hope to see you all in Puerto Rico for #2025SDB !!!

[Ondine Cleaver @cleaverlab]

🥰

[@LaBonneLaB @labonnelab]

LOVE these awesome #Embryo22 #WomeninSTEM You guys rocked this meeting and woohoo @MathiThiru95 on the award

[John Wallingford @jbwallingford]

Huge congrats to Dan Dickinson for winning the ⁦@SocDevBio⁩ Betty Hay Award at #2024SDB! ⁦@ut_mbs⁩

[NAVBO @vascularbiology]

Deadline for ABSTRACT submission: August 1!

Plan to attend Vascular Biology 2024 in California, October 20-24, 2024 at Asilomar Conference Grounds.

Details: https://t.co/0KTRr6JYOK