Our paper on condensates functionalization with molecular motors is out in @embojournal! We were able to spatially control the nucleation of condensates and we showed the possibility to change the localisation of a target RNA.
What gives Condensates + Motors ?
By creating motor-driven condensates in cells, we show how active transport shapes condensate formation. This also provides a unique approach to manipulate subcellular mRNA localization.
https://t.co/b2OyCQirEe
#FISH-quant is a modular analysis toolbox for single-molecule RNA FISH images, from RNA detection to the description of RNA localization patterns https://t.co/lKowWWB1M2
What sets condensate size in cells ?
Latest story with @cochard_audrey and D.Weil reveals key roles of RNA and viscoelastic properties
https://t.co/p1FJdGBSao
By creating artificial granules in cells, we show that the size of #condensates scales with RNA surface density.
RNA at the surface of phase-separated condensates impacts their size and number
https://t.co/nmuULhf3hw
Our preprint with @cochard_audrey and D.Weil team is out!
By recreating artificial RNP granules in cells, we show that the size of #condensates scales with RNA surface density