Dr. Jackson

Eco-liberal EU-expat (now in US PNW). Coder (Java), OSS author (Jackson, Woodstox, ClassMate, java-uuid-generator), collaborator, mentor. Gainfully employed.

[Dr. Jackson @cowtowncoder]

Who the hell decided to call them "Containers" and not "Code Cubicles"?!

[Michael Lin, MD PhD 🧬 @michaelzlin]

To understand how politics has damaged the reputation of scientific knowledge in the US, just consider our society is assigning $1T to Anthropic value because its CEO promised to cure all diseases when every single person who has actually tried developing a drug says it's a lie

[Dr. Jackson @cowtowncoder]

@LeventeZone right, fingering I hadn't even thought about (but obvious once it is mentioned). And yeah, theoretically LLMs could learn those aspects with enough material but... then again, what would be the point.

[Dr. Jackson @cowtowncoder]

Interesting how the whole "details are right but the bigger picture not [super-structure a mess]" affects both Code and generated music -- https://t.co/lXFjdTgw7P

[imjustnewatai @imjustnewatai]

I asked Claude Fable 5.2 to write a Beethoven-style piano sonata movement in LilyPond. It wrote the score, recorded it, and made this video. Every note you see is from its source file.

[lifcc @mylifcc]

继 Vibe Coding 之后，硅谷今天连 Vibe Archaeology（氛围考古学） 都搞出来了，而且剧情在 24 小时内完成了史诗级反转。
一位 Google 工程师去南美旅游时突发奇想：既然激光雷达（LiDAR）能穿透雨林树冠看到地面，能不能直接扔一堆 AI Agent 去找还没被人类发现的玛雅金字塔？
他睡前跑通了一套极其暴力的流水线，不到 72 小时就收到了墨西哥政府的官方回函——结果评论区顺着论文一扒，扒出了一个令所有做 Agent 的人后背发凉又忍不住笑出声的细节。
https://t.co/cKc7tAGUPP

[Melinda B. Chu @MelindaBChu1]

🚨There is 0% this is possible. If you are developing drugs 🔺dementia or diseases with long-term follow-up, 🔺

🚨You can’t have a 12-week study and say you cured dementia. A participant has to be followed at least 12 months to 24 months.

Your trial at Phase 2 and 3 is going to be a minimum of 24 months; will say Phase 1 12 months (that’s 5 years in trials)

Fastest 6, 7-8 years with some kind of breakthrough designation. No one’s fault that’s the biology.

==
Ok, let’s say discovery and even synthesis of a compound takes 1 day (takes weeks to months) I’ll even say animal studies and IND take 12 months. So with human trials even if everything goes perfectly.

🚨 So it’s 6 or 7-8 years to approval even with some kind of breakthrough designation.

Also, they have zero drug candidates. A normal
thing to say after this is “we’re seeing progress in the lab”, but they don’t have anything.

It’s not being negative. It’s just not possible to assess a long-term outcome in a short time frame.

[Bahrad Sokhansanj @bahradx]

I hope everyone understands that the reason why Dario Amodei thinks he can eliminate mental illness in 10 years isn't because he's going to develop a drug that requires long-term follow up. It's by embryo screening. He wrote about it in Machines of Loving Grace in October 2024.

[Anton Zhiyanov @ohmypy]

Remember eMudhra with their Most Secure Private Key Of All Times?

So here's how they managed to do it:

1) They exported a private key from the hardware security module (HSM) into a regular PC (!).

2) They processed this private key with a Python script they wrote (!!).

3) The script had a bug that ruined the key by truncating it to a single byte (!!!).

4) They imported the ruined key back into the HSM and certified it with the root CA.

But that's not the end of it. After the initial "ceremony", the HSM held two keys: the good original and the ruined copy.

A month later, this is what happened:

1) The certificates contained the ruined copy's public key, but the revocation lists (CRLs) were signed with the good original, so their signatures failed to verify.

2) Instead of investigating the problem, eMudhra "fixed" it by signing the CRLs with the ruined key instead.

3) The weak keys went unnoticed until an outside researcher reported them in October 2026.

Good job!

[Jade Cole @JadeCole2112]

Get ready for "unexpected" to enter the lexicon a lot in the next few months.

[Ben Justman🍷 @BenJustman]

A girl just made eye contact with me.
Nice try China.

[Caitlyn’s Pup @kaitlynspup]

The cute girl at the Panda Express drive thru window slipped me a free egg roll. Not today, Ms. Chinese Honey Pot. Not. Today.

[Geoff Shullenberger @g_shullenberger]

If you can’t see at least some parallels with Elizabeth Holmes here I don’t know what to tell you…

[John Bumstead @RDKLInc]

Decided to finally see what this AI thing is all about

[Jeff Timmer @jefftimmer]

Do yourself a favor and read the comments. Seriously, all the comments. Right now. 😂

[Gergely Orosz @GergelyOrosz]

I CANNOT believe the report: it proves that eMudhra is a clown show, and was never fit to be a CA:

The point of a HSM (hardware security module) is that the private key NEVER leaves it. Guess what eMudhra did: it turned off FIPS mode (WTF?!) and copied out the private key 😱

[Michael Morelli @morellifit]

This new tirzepatide study is eye-opening.

120 adults took the drug for 40 weeks, and half of them also lifted weights 3x a week. Both groups lost about 50 lbs.

But when they tested strength, the two groups looked nothing alike.

Here's the breakdown: (1/11)

[Hiro Protagonist (至大) @augeeidos]

The flying Roadster was just a more sophisticated version of the fake supercomputer case he was running back when he started Zip2 to make his first millions.

[Dr. Jackson @cowtowncoder]

Did not know that they were/are so dangerous… https://t.co/04BPbbY6VK

[Nora | CEO of Mega Evolution 👾 @norainthefuture]

this is one of the more insidious parts of ai proliferation – people lose their skills & that capability is sold back to them when they can’t do their work without it

[Zack Voell @zackvoell]

Overheard in Austin:

“I think that guy is listening to our conversation”