Jeff McCracken

I bring cutting-edge technology to life in the utility industry. Improving environmental sustainability through innovation is my passion.

[Bjorn Lomborg @BjornLomborg]

Good news you probably haven't heard:

The Great Barrier Reef's five best years of coral cover in the 40-year record are the five most recent.

After decades of predictions of its imminent demise, the reef stubbornly refuses to die.

My new @latimes op-ed:
https://t.co/YWYdK7CKuJ

[Dr. Alex Tatem @DrAlexTatem]

Today I testified before the FDA's Pharmacy Compounding Advisory Committee to advocate for patient access to BPC-157, TB-500, KPV, and MOTS-c.

The committee voted to recommend moving all four peptides forward—but this is not final FDA approval. There are still important steps ahead.

I break down exactly what happened, what this vote actually means, and what comes next.👇

[Jeff McCracken @cracken25]

@DrAlexTatem Alex, What did you say to them?

[Jesse Morse, M.D. @DrJesseMorse]

BPC-157 ✅
TB-500 ✅
MOTS-c ✅
KPV ✅

4/4 peptides approved today 💪🏻

[Boris Cherny @bcherny]

1/ Auto mode = no more permission prompts

Opus 4.7 loves doing complex, long-running tasks like deep research, refactoring code, building complex features, iterating until it hits a performance benchmark.

In the past, you either had to babysit the model while it did these sorts of long tasks, our use --dangerously-skip-permissions.

We recently rolled out auto mode as a safer alternative. In this mode, permission prompts are routed to a model-based classifier to decide whether the command is safe to run. If it's safe, it's auto-approved.

This means no more babysitting while the model runs. More than that, it means you can run more Claudes in parallel. Once a Claude is cooking, you can switch focus to the next Claude.

Auto mode is now available for Opus 4.7 for Max, Teams, and Enterprise users. Shift-tab to enter auto mode in the CLI, or choose it in the dropdown in Desktop or VSCode.

[ThePeptideList @PeptideList]

Everyone's talking about retatrutide for weight loss (28.7%). Almost nobody's talking about what it does to your liver.

More than 80% reduction in liver fat. Over 90% normalization rates. In a body composition substudy from the Phase 3 program.

100 million Americans have fatty liver disease. Most don't know it. There's no FDA-approved treatment for it besides "lose weight and hope."

Retatrutide's glucagon receptor activation appears to directly target hepatic fat metabolism not just as a side effect of weight loss, but as a primary mechanism.

This isn't a weight loss drug that happens to help your liver. It might be a liver drug that happens to cause weight loss.

Phase 3 weight loss data drops first half of 2026.
Watch this space.

[Claude @claudeai]

Introducing Code Review, a new feature for Claude Code.

When a PR opens, Claude dispatches a team of agents to hunt for bugs.

[Curiosity @MAstronomers]

🚨This is wild: CRISPR gene-editing removed HIV DNA from infected cells — and those edited cells didn’t get infected again when exposed. Science is starting to rewrite the rules. 🧬⚡

[NBC Sports @NBCSports]

South Korea’s Choi Gaon strikes GOLD in the women’s halfpipe! 🥇

[Matt Shumer @mattshumer_]

https://t.co/ivXRKXJvQg

[Wellness Xplorer @WellnessXplorer]

This is how ultra-processed meals shapes your kid's growth

[🇦🇺Craig Tindale @ctindale]

https://t.co/yZdHV8z6LR

[Massimo @Rainmaker1973]

J.H. Klaebo has completed a sub-six-minute mile pace uphill on skis.

May be the single greatest athletic feat of all time.

[Jeff McCracken @cracken25]

https://t.co/iZyBbfkW8k

[Rick Rule @RealRickRule]

I hope this makes, or saves, you some money

[Jeff McCracken @cracken25]

Please stop posting “this guy literally …”

[Massimo @Rainmaker1973]

Urgent Rescue on the Slopes in Niseko, Hokkaido, Japan.

A Ski patrol was transporting an injured skier downhill on a stretcher while performing CPR.
https://t.co/oNw3FXsF1z

[Science girl @sciencegirl]

A compilation of gravity-defying skill and precision

[Colin McCarthy @US_Stormwatch]

One week. That’s all it took.

@palisadestahoe has picked up 12+ inches of precipitation and 60+ inches of snow on the upper mountain.

The greater Tahoe Basin's snowpack has jumped from 18% to 81% of normal in just 8 days.

And total precipitation is now 141% of normal!

[Cristina Tejera @cristinatejerap]

The evolution of C-peptide's role in diabetes care. #currentopinioninendocrinology

https://t.co/lb9VoJVc2h