After thousands of microscope hours and several years of painstaking optimisation, @glynnca93 and I are very excited to share our latest manuscript. We outline our approach to investigate the molecular organisation within hippocampus tissue using cryo-ET.
it was great to share some results from mine & @glynnca93's latest preprint! It has been an interesting meeting with plenty of overlap between different imaging modalities/sample prep disciplines. Lots of insightful discussion/ideas!🔬
@VolumeEM1
Jake Smith (@crying_EM), PhD student at the Franklin and @UniofOxford , gave a fascinating talk this afternoon about his PhD work studying the hippocampus using cryo-EM as part of the vEM Technology Forum's Cryo FIB-SEM Methods Development Session. #vEMTechForum2024 @VolumeEM1
A huge shoutout to the rest of the team at the Franklin for making this happen.
And of course the biggest shoutout to Michael Grange (now twitter-less) for steering the ship🫡.
On to the next one 👀🧠🔬
We hope that our structural and cell biology friends can adapt our approach to their favourite tissue biology question.
To find out more, please check out our preprint: https://t.co/4SIVP29qEZ
#teamtomo#LiftLaughLove
Our high-resolution (2.2 Å) in situ structural work reveals details of translational landscape, with various cofactors and antitumor drug/inhibitor, all directly within human cells!
https://t.co/ScWOAQRjTw