Eugen

Affective Neuroscience - Mood Disorders - Eastern Philosophy - Neuropharmacology - Lipid Metabolism -Psychology & Phenomenology of Emotions - Chimneysweeper

[Eugen @CTCaveman]

@DaaveeAr The effect of metformin on mitochondria has been known for a long time.
Part of why it can raise the risk of lactic acidosis.

Wtf are you smoking

[Eugen @CTCaveman]

@DoxepinHCl A lot. Effect sizes aside, in patients with agitated depression phenotype it can increase restlessness and dysphoria.

There is no “first-line” - depression is not a monolith. Individualised treatment.

Bupropion would work for anhedonia but it ain’t a silver bullet

[Spencer Hakimian @SpencerHakimian]

Iran social media going nuclear

[Eugen @CTCaveman]

@tylerblack32 Fair. I hate the phrase too.

But phasic dopamine release would count as a dopamine hit, no?

[Eugen @CTCaveman]

@xmaximus242x @edsocra Going to use this to justify my failures: “I am not an accolade collector. I am a real one”

[Eugen @CTCaveman]

@ick_real Fuck you

[Eugen @CTCaveman]

@Senevigrof @jarofsmegma But you are the exception. Of course

[Eugen @CTCaveman]

@XiWellWisher Did you win anything in your life? Brain damage prolly

[Eugen @CTCaveman]

@cenkuygur Correct. However when assessing courage you so have to take age into account

[Eugen @CTCaveman]

@Gonzalez_JT @LoreofRunning1 Hahahahahah amazing really

[Eugen @CTCaveman]

@severesarcasm @EricTopol Vo2 dog!!

[Eugen @CTCaveman]

@AMMALEX950 @FreckledLiberty Cretin

[Eugen @CTCaveman]

@2Finkle89738 Not meth “dawg” - meth is tenfold at least more potent at releasing dopamine at comparative doses and it is neurotoxic

Dawg

[Eugen @CTCaveman]

@emkenobi Porn addiction and yet you are posting porn.

That is like selling alcohol and then complaining how bad alcohol it is

Your brain is “castrated”

[Eugen @CTCaveman]

@JacobmeyerJohn @Nature “Malignant neoplasm” do you even know what are you talking about?

A neoplasm is by, definition, fucking “malignant”

[Eugen @CTCaveman]

@Xmira_belle @grok “Do it” what a loser

[Eugen @CTCaveman]

@jinjung @joeroganhq INCORRECT

[Eugen @CTCaveman]

@bryan_johnson Can you define depression?

[Lucian Fogoros @fogoros]

Most people are terrified AI will take their jobs because they confuse their tasks with their purpose.
Jensen Huang explains it perfectly: If you watched a CEO all day, you would think their job is "typist" because they spend most of their time typing emails. If AI automates typing, the CEO doesn't lose their job. They just have more time to lead.
The same applies to everyone. When AI automates the tasks, it enhances the purpose.
Stop measuring your value by your to-do list. Your value is the purpose behind it.

[Wirelyss 👁️‍🗨️💫 @wirelyss]

@elonmusk how I picture @elonmusk's keyboard